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Removing a TextTrackRegion from a the TextTrackRegionList of a TextTrack can be done now as a side-effect of addRegion() - however, I think there should be an explicit method, e.g. removeRegion(), to do this.
I've added removeRegion() function to TextTrackRegion. See: https://dvcs.w3.org/hg/text-tracks/rev/3f0ef4d6f3a8
To be clear: it's added to TextTrack, sorry.