<ericP> heya lena

<ericP> it appears i never made a res for this meeting

<ericP> there's nothing after it, is there?

<ericP> how many folks do you expect?

<Lena> shall we openup for 10?

<ericP> sure, we can shoot higher, just in case

<Lena> ok,.... 20?

<Lena> nothing after this, I think

<ericP> let's say 15, in order not to alarm others

<ericP> hmm

<ericP> lodd was scheduled from 15-1600Z

<ericP> i guess the list changes at 10mins to the hour

<ericP> there won't be an LODD, will there?

<ericP> doesn't matter

<ericP> Wednesdays 15:00-16:00 UTC (11:00am-12:00pm Boston local)

<ericP> Zakim Bridge +1.617.761.6200, conference 4257 ("HCLS")

<ericP> 15 participants

<YolandaGil> Hi Lena and all!

<YolandaGil> Slides are at http://www.isi.edu/~gil/slides/W3C-SystemsBiologyTF-14March2012.pdf

<ericP> heya YolandaGil

<ericP> sorry i'll miss your talk. will be on another telecon

<jun> Hi lena

<Lena> is the echo gone?

<oliver> hi

<Lena> https://deri.webex.com/deri/e.php?AT=WMI&EventID=204980932&PW=2848010d052822202b35&RT=MTgjMjE%3D

<Lena> slides: http://www.isi.edu/~gil/slides/W3C-SystemsBiologyTF-14March2012.pdf

<ericP> oliver, who is here?

<markw> What is the WebEx password?

<Lena> http://www.w3.org/wiki/HCLSIG/SysBio/20120314

<Lena> slides: http://www.isi.edu/~gil/slides/W3C-SystemsBiologyTF-14March2012.pdf

<jun> Are we using IRC for scribing?

YolandaGil: characteristics of the data are often lost
... metadata not preserved when moved from one application ot the next
... detective work to figure out where the data came from
... important to mine the metadata as we process it
... in wings, metadata is used in several ways, e.g. set parameters
... 3 different ways to doa certain step - how to choose one dinamically?
... wings wil dynamiclly adapt the model according to the input data
... this is possible because karma + wings are provenance awarre
... (slide 8)
... in wings, every workflow has a data flow - every component has a variable associated with it, which means we can add contrains
... all this is done using rdf and owl and making full use of sem web technologies
... slide 11
... using propagation to find workflows (e.g. based on some type of data or using some algorithm)
... slide 12
... slide 17 - image analysis
... slide 18 - workflow sharing
... population genomics
... slide 19 - using constrains on the different components
... slide 20 - finding out how reproducible the results from research are
... duerr et al science 2006
... using an open workflow, the results are made reproducible
... slide 21 - using more modern algorithms, was able to reproduce the results by replicating the workflow
... slide 23 - replicated workflow for drug discovery (based on kinnings et al 2010)
... same workflow should be applicatble to other diseases
... slide 24 - problems: people have different prefernces on which code to use
... so wings is independent of the computational statistics platform
... slide 25 - worflow publication is abstract; also published as links data
... slide 28 - developed extension to OPM to describe workflows
... soon going to develop an extension to prov standard!
... slide 29 - everything in the workflow end us as linked data with links for the source code, the datasets, etc
... slide 32 - high school students can use it to do productive work!
... discovery informatics - extending data with semantic models reprsentation, data discovery, etc

<Lena> carole: data in mexperiment?

<Lena> michael: in myexperiment, we are tied to the application to run it again - how to make that more general?

<Lena> carole: workflow4ever - represening workflows as a part of great collection

<Lena> carole: share provenance execution logs (myexperiment 2.0)

<Lena> YolandaGil: when the workflows are exported, code is made available

<Lena> carole: workflows for systems biology? (e.g. model validation)

<Lena> jun: very expensive to replicate workflows/set up the services for the worflow

<Lena> jun: if we want to use wings, how much effort would be involved?

<Lena> YolandaGil: 3 mo of work

<Lena> YolandaGil: biologist may take longer

<Lena> YolandaGil: correction - 3 mo for the drugs project; high school kids have it running in 1 day!

<Lena> YolandaGil: software interoperability by creating class of components

<dgarijo> I am here, I can listen to you!

<Lena> RRSAgent: please draft the minutes

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        <dbooth> Present: dbooth jonathan mary
        <dbooth> Present+ amy


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<dbooth> Meeting: Weekly Baking Club Meeting


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Got date from IRC log name: 14 Mar 2012
Guessing minutes URL: http://www.w3.org/2012/03/14-HCLS-minutes.html
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<dbooth> Topic: Review of Amy's report