DSE: public or members only?

action+ First steps: clinical data standards

<scribe> ACTION: First steps: clinical data standards [recorded in http://www.w3.org/2006/09/15-hcls-minutes.html#action01]

Jim at meeting now, working on HL7 + CDISC messaging around biomarkers

scribe: controlled vocabulary challenges around genetic markers and mutations, how to define for researchers and clinicians. Flat reps will not be enough...
... LOINC codes vs SNOMED, how to reconcile differences and ambiguities.

Jim thinks many vocabularies have a high degree of "good-enough" overlap

Kerstin: need to build up more concepts on bio molecules and observations; can SW help add these concepts over time

Jim: LOINC linear mapping of terms for lab test; how to eventually handle multiple lab tests...

Can we convince the clin stds groups to use RDF-OWL to begin mapping and versioning the vocabs with each other?

Scenarios: Develop one out in more detail, and implement some form of demo around them; could then be shown within pharma orgs as POC

<scribe> ACTION: Discuss with Ivan Herman on W3C limited view of DSE activities [recorded in http://www.w3.org/2006/09/15-hcls-minutes.html#action02]

Kerstin: better data integration, starting with SDTM : recombinant clinical data ala SW

Jim: handling data and communications with external collaborators

<tslater> Ted: semantic web techniques could play an important role in information flow from clinical to pre-clinical and back.

Jim: possibly show SDTM may can have better controlled content definitions

Bo: scenarios -> specific examples

Jim: use cases on specific pain points...

Bo: connect use-cases to an overall larger model

<scribe> ACTION: use cases from everyone by next week [recorded in http://www.w3.org/2006/09/15-hcls-minutes.html#action03]

<tslater> ACTION: Ted will talk to colleagues to see who can make it to Amsterdam, esp. Development Informatics colleagues. [recorded in http://www.w3.org/2006/09/15-hcls-minutes.html#action04]

Kerstin: Janus is for re-usability of all clinical data
... Janus: storage model for clinical data, not just data exchange

Jim: Better data extraction and formatting

Kerstin: regulated and sensitive data, but somehow include provenance and open up for analysis

Can references and annotations be made on top of Janus without contaminating it?

Jim: how to have scientists make use and annotate Janus-based data for translational medicine

<scribe> ACTION: Define schedule for DSE conf calls at F2F [recorded in http://www.w3.org/2006/09/15-hcls-minutes.html#action05]

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Possibly Present: Bo DSE Jim Kerstin Scenarios Ted jimmcg tslater
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        <dbooth> Present: dbooth jonathan mary
        <dbooth> Present+ amy


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Got date from IRC log name: 15 Sep 2006
Guessing minutes URL: http://www.w3.org/2006/09/15-hcls-minutes.html
People with action items: define discuss first talk ted use will

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