TMO Review MD
Review of Translational Medicine Ontology
MichelDumontier tried to assess the utility of each term in the translational medicine ontology with the topic that it might be part of.
! : new term
Business
- Patent
- Market
- Company
- Cost Benefit Analysis
Experiment (ontologies: OBI/PATO, SO, SWAN)
- Activity [-vague]
- Animal Study
- Antibody
- Assay
- ! Sequence
- ! Experimental Result
- Measure
- Observation
- Phenotype
- Sample
Mechanism of Action (ontology: BioPAX, Protein, Cell Type, Chebi, CO)
- ! Interaction
- Complex Formation
- ! Drug Interaction
- Material Entity
- Protein
- Gene
- ! Cell / Cell Line
- Tissue
- ! Organ
- Gene Expression / Gene Expression Profile
- Pathway
- ! Metabolic Pathway
- ! Signalling Pathway
- Molecular Role
- Receptor
- Target
- Regulator
- ! Activator
- ! Repressor
- ! Enzyme
- Drug Metabolizing Enzyme
- SNP
Drug Discovery (Chebi, CO)
- Chemical property
- ! hydrogen bond donors / acceptors
- ! hydrophobicity
- ! size
- Chemical similarity
- ! Chemical
- Drug
- ! Chemical Structure
- Efficacy
- Pharmacophore
Translational
- Animal Model
- Biomarker
- Toxicity
Clinical
- Adverse Event / Side Effect
- ClinicalTrial
- Diagnosis
- Disease
- Symptom
- Prognosis
- Population
- Patient
- Clinician
- Treatment / Therapy
- Treatment Management Plan
Formulation
- Ingredient
- Active Ingredient
- Amount
- Dose
- ! Excipient
- Unit
Significance Unknown
- Intervention
- Risk [ market? drug? ]
Discards
- Dosage [replaced by dose]
- BioProcess [vague]
- Bioassay [-redundant with Assay]
- Bioinformatics [topic/vague]
- Biologic [vague]
- Cheminformatics [topic/vague]
- Competitor [unnecessary]
- Compound [replaced by chemical]
- DifferentialDiagnosis [medical practice]
- Discipline [vague]
- DiseaseSymptoms [replaced by Symptoms]
- DrugNonDrugInteraction [probably unnecessary - better to search on specific kinds of interactions]
- Fragment [unclear]
- ExperimentalOutput [ replaced by Experimental Result]
- GenomicSequence [replaced by Sequence]
- ImmuneResponse [clinical]
- InactiveIngredient [replaced by Excipient]
- Information [vague]
- MolecularStructure [replaced by Chemical Structure]
- Outcome
- PatientDiagnosis [covered by Diagnosis]
- PatientPrognosis [covered by Prognosis]
- Payer [unrelated]
- Person [vague]
- Pharmacology [topic]
- Polypharmacology [unknown]
- Project [vague]
- Referral [medical]
- Resource [vague]
- Role [vague]
- Scaffold [unnecessary]
- Signaling *
- Solution [too detailed]
- Synthesis [too industrial]
- Test [replaced by experiment]
- Toxicology [replaced by Toxicity]
- TherapeuticCostBenefit [replaced by Cost Benefit Analysis]