14:58:02 RRSAgent has joined #hcls 14:58:02 logging to http://www.w3.org/2010/06/07-hcls-irc 14:58:11 Zakim, this will be BioRDF 14:58:11 ok, kei, I see SW_HCLS(BioRDF)11:00AM already started 14:58:28 agenda+ introduction [kei] 14:58:36 agenda+ lipid ontology [chris] 14:58:56 agenda+ genelist representation [Lena, Jun, Satya, Scott] 14:59:07 Zakim, take up next agendum 14:59:07 agendum 1. "introduction" taken up [from kei] 14:59:48 +Kei_Cheung 14:59:53 + +1.832.386.aabb 15:01:18 mscottm has joined #hcls 15:01:40 michael has joined #hcls 15:02:40 + +1.206.605.aacc 15:04:31 https://transfer.med.yale.edu/upload/data/39YObdi808qV4ftL3FY1588AL5AAC2AKLpS/Baker_-_BioRDF_-_W3C_-_HCLS_Lipid-Ontology_and_Reuse_Cases.pptx 15:04:50 https://transfer.med.yale.edu/upload/data/39YObdi808qV4ftL3FY1588AL5AAC2AKLpS/Baker_-_BioRDF_-_W3C_-_HCLS_Lipid-Ontology_and_Reuse_Cases.pdf 15:04:50 Cheers, 15:04:50 -Kei 15:07:15 +mscottm 15:07:42 Zakim, please dial ericP-office 15:07:42 ok, ericP; the call is being made 15:07:44 +EricP 15:08:35 +[IPcaller] 15:08:52 Zakim, who is here? 15:08:52 On the phone I see +1.506.648.aaaa, Kei_Cheung, +1.832.386.aabb, +1.206.605.aacc, mscottm, EricP, [IPcaller] 15:08:54 On IRC I see michael, mscottm, RRSAgent, Zakim, kei, LenaDeus, jodi, Chris, matthias_samwald, trackbot, ericP 15:09:02 jodi has left #HCLS 15:09:23 +??P9 15:10:38 Zakim, +[IPcaller] is matthias_samwald 15:10:38 sorry, mscottm, I do not recognize a party named '+[IPcaller]' 15:10:39 rfrost has joined #HCLS 15:10:43 Zakim, [IPcaller] is matthias_samwald 15:10:43 +matthias_samwald; got it 15:11:07 Zakim, ??P9 is rfrost 15:11:07 +rfrost; got it 15:11:25 + +1.937.775.aadd 15:12:56 kei, would you mind repasting the slide link? 15:13:11 kei: lipid ontology -- started with text mining and then formal ontology 15:13:14 ssahoo2 has joined #HCLS 15:13:41 kei: data integration is important and challenging in the context of lipid 15:14:11 IUPAC is older (1970's) challenge in adoption 15:14:32 LIPIDMAPS came along but still has issues such as inconsistencies 15:14:57 objectives: available through OBO 15:15:43 OBO compliance (e.g., continuant entity ... small molecule) 15:16:30 semantically expressive 15:17:15 use of owl in terms of necessary and sufficient condiitions and cardinality 15:18:03 started with 32 organic groups and another 63 are needed to define lipids 15:20:39 different functional groups can be defined 15:21:52 some entities are from the lipidmap and new entities have been added 15:22:59 reasoning can be performed based on the owl structure 15:23:51 use of checkmol and open babel for conversion into n3 format from mol files 15:25:02 go through all the instances and use rules/axioms to reason over the structure 15:25:22 to make sure structural group assignments are correct 15:25:42 this is an iterative process with interaction/collaboration/curation with community 15:26:31 715 classes, 901 restrictions, and 41 properties 15:26:52 scientists discovering new lipids can submit through web services 15:27:27 position the ontology as a bridge between lipid community, obo, and chebi 15:27:47 leverage the skills of the ontology community and the expertise of lipid community 15:27:57 semantic assistant 15:28:40 use of racer, sparql, and other related tools 15:29:24 use of text mining to help populate the ontology 15:30:03 normalizing terms into canonical names 15:30:58 looked at 8000 abstracts involving ovarian cancer 15:31:19 linked dimensions of lipid/protein to classes 15:31:32 linked to the sentence level 15:32:39 signal pathways are also included 15:33:17 knowledge finder: user can submit keyword can be mapped to a set of natural language queries for users to select 15:33:37 in addition, visual query tool has been developed 15:34:36 semantic desktop assistant: web service paradigm 15:35:22 lipid annotation: input can be abstract text for example 15:35:39 using the GATE annotation pipeline 15:36:56 client side application is open office 15:37:06 semantic assistant is free for download 15:39:31 acknowledgement: mutliple institutions are involved 15:41:21 (need to leave now as well. bye!) 15:41:25 -matthias_samwald 15:42:31 thanks, matthias 15:43:11 scott, could you also do the scribing from this point on? 15:45:31 I'm leaving now ...thanks! 15:46:00 mib_jgvzpy has joined #hcls 15:47:26 -Kei_Cheung 15:52:39 - +1.937.775.aadd 15:52:55 -EricP 16:02:04 -rfrost 16:07:59 michael has left #hcls 16:08:02 - +1.832.386.aabb 16:08:05 -mscottm 16:08:06 - +1.206.605.aacc 16:08:06 - +1.506.648.aaaa 16:08:08 SW_HCLS(BioRDF)11:00AM has ended 16:08:10 Attendees were +1.506.648.aaaa, Kei_Cheung, +1.832.386.aabb, +1.206.605.aacc, mscottm, EricP, matthias_samwald, rfrost, +1.937.775.aadd 16:08:38 possible followup meeting to look at genelists: Thu morning HCLS timeslot 11AM ET 16:09:34 Lena: Have some concerns about the current relation between genes and samples 16:09:55 Scott: Yes, let's talk about that some more - possibly this week? 16:10:27 ..anybody else interested in this? 16:10:28 MichaelMiller: I would be interested 16:28:55 RRSAgent, please draft minutes 16:28:55 I have made the request to generate http://www.w3.org/2010/06/07-hcls-minutes.html mscottm 16:28:59 RRSAgent, please make log world-visible 17:17:25 matthias_samwald has joined #hcls 17:17:38 matthias_samwald has left #hcls