HCLSIG/Terminology/PathRadCorrelation/ExamplePathReport5

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         DETAIL TEST   SPCH                                                                                                       
                                                                                                                                  
                   Right breast mass.                                                                                             
                                                                                                                                                                                                                                                                     
                                                                                                                                  
         DETAIL TEST   SPCPT                                                                                                      
                                                                                                                                  
                   Container A-G: 88307/FR                                                                                        
                                                                                                                                  
                                                                                                                                  
         DETAIL TEST   SPGD                                                                                                       
                                                                                                                                  
                   A. "Sentinel node number one". Received fresh and placed in formalin is a 1.5                                  
                   x 1.0 x 0.3 cm fragment of adipose tissue submitted entirely in block A1.  A                                   
                   cytokeratin stain has been prospectively requested on block A1.                                                
                                                                                                                                  
                   B. "Sentinel node number two". Received fresh and placed in formalin is a 2.0                                  
                   x 1.5 x 1.0 cm adipose tissue dissected for lymph nodes. One bisected lymph                                    
                   node is submitted in block B1. A cytokeratin stain is prospectively requested                                  
                   on block B1.                                                                                                   
                                                                                                                                  
                   C. "Sentinel node number three". Received fresh and placed in formalin is a                                    
                   2.5 x 1.0 x 0.2 cm fragment of adipose tissue submitted entirely in block C1.                                  
                   A cytokeratin stain has been previously requested on block C1.                                                 
                                                                                                                                  
                   D. "Sentinel node number four". Received fresh and placed in formalin are                                      
                   three fragments of fibroadipose tissue measuring 1.5 x 1.5 x 0.3 cm in                                         
                   aggregate submitted entirely in block D1. A cytokeratin stain is prospectively                                 
                   requested on block D1.                                                                                         
                                                                                                                                  
                   E. "Sentinel node number five". Received fresh and placed in formalin is a 2.0                                 
                   x 1.0 x 0.3 cm fragment of fibroadipose tissue submitted entirely in block E1.                                 
                   A cytokeratin stain has been prospectively requested on block E1.                                              
                                                                                                                                  
                   F. "Right breast mass needle localization", received fresh and placed in                                       
                   formalin. A 7.7 (A-P) x 1.6 (M-L) x 6.6 (S-I) cm breast biopsy is oriented                                     
                   long suture lateral and short suture superior. The specimen is inked                                           
                   superior-red, inferior-yellow, medial-blue, and lateral-black. Sectioning from                                 
                   anterior to posterior demonstrates an approximately 2.6 x 0.7 x 0.7 cm white                                   
                   mass located in the center of the specimen abutting the black ink, 0.8 cm from                                 
                   the yellow margin, 0.5 cm from the blue and 2.3 cm from the red margin.                                        
                   Radiograph reveals a clip in the middle of the mass. The breast tissue                                         
                   adjacent to the mass is discolored by blue dye. Approximately half of the                                      
                   specimen is submitted as follows (note that some of the slices have been                                       
                   further sectioned due to thickness):                                                                           
                                                                                                                                  
                   BLOCK SUMMARY:                                                                                                 
                                                                                                                                  
                   F1- tangential anterior margin.                                                                                
                   F2-F5- representative sections anterior to mass.                                                               
                   F6-F17- mass (clip in F12)                                                                                     
                   F19- representative section posterior to mass.                                                                 
                   F20- tangential posterior margin.                                                                              
                                                                                                                                  
                   G. "Right breast mass inferior margin", received fresh and placed in formalin.                                 
                   A 4.5 x 3.0 x 1.0 mm fragment of adipose tissue is marked with suture at final                                 
                   margin which inked blue, tangentially removed and submitted in blocks G1-G3.                                   
                                                                                                                                  
                   H. "Right breast superior margin", received fresh and placed in formalin. A                                    
                   3.5 x 3.0 x 1.2 cm fragment of adipose tissue is marked with suture at final                                   
                   margin which is inked blue, tangentially removed and submitted in blocks                                       
                   H1-H2.                                                                                                         
                                                                                                                                  
                   I. "Right breast inferior margin", received fresh and placed in formalin. A                                    
                   3.5 x 2.0 x 0.7 cm fragment of adipose tissue is marked with a suture on final                                 
                   margin which is inked blue, tangentially removed, and submitted in block I1.                                   
                                                                                                                                  
                   J. "Right breast lateral margin", received fresh and placed in formalin. A 4.0                                 
                   x 2.0 x 1.5 cm fragment of adipose tissue is marked with suture on final                                       
                   margin which is inked blue, removed tangentially and submitted in block J1.                                    
                   Also in the container is a 2.5 x 2.0 x 0.3 cm fragment of freely floating                                      
                   adipose tissue submitted entirely in block J2.                                                                 
                                                                                                                                  
                          Dr. White/Dr. Green/slides to Dr. Brown                                                         
                                                                                                                                  
                                                                                                                                  
         DETAIL TEST   SPMI                                                                                                       
                                                                                                                                  
                   Microscopic examination is performed.                                                                          
                                                                                                                                  
                                                                                                                                  
         DETAIL TEST   SPDX                                                                                                       
                                                                                                                                  
                   A. "SENTINEL NODE #1" (EXCISION):                                                                              
                                                                                                                                  
                       NO CARCINOMA IDENTIFIED IN ONE LYMPH NODE (0/1).                                                           
                       IMMUNOHISTOCHEMICAL STAIN FOR CYTOKERATIN IS NEGATIVE.                                                     
                                                                                                                                  
                                                                                                                                  
                   B. "SENTINEL NODE #2" (EXCISION):                                                                              
                                                                                                                                  
                       NO CARCINOMA IDENTIFIED IN ONE LYMPH NODE (0/1).                                                           
                       IMMUNOHISTOCHEMICAL STAIN FOR CYTOKERATIN IS NEGATIVE.                                                     
                                                                                                                                  
                                                                                                                                  
                   C. "SENTINEL NODE #3" (BIOPSY):                                                                                
                                                                                                                                  
                       NO CARCINOMA IDENTIFIED IN ONE LYMPH NODE (0/1).                                                           
                       IMMUNOHISTOCHEMICAL STAIN FOR CYTOKERATIN IS NEGATIVE.                                                     
                                                                                                                                  
                                                                                                                                  
                   D. "SENTINEL NODE #4" (BIOPSY):                                                                                
                       NO CARCINOMA IDENTIFIED IN TWO LYMPH NODES (0/2).                                                          
                       IMMUNOHISTOCHEMICAL STAIN FOR CYTOKERATIN IS NEGATIVE.                                                     
                                                                                                                                  
                                                                                                                                  
                   E. "SENTINEL NODE" (BIOPSY):                                                                                   
                                                                                                                                  
                       NO CARCINOMA IDENTIFIED IN ONE LYMPH NODE (0/1).                                                           
                       IMMUNOHISTOCHEMICAL STAIN FOR CYTOKERATIN IS NEGATIVE.                                                     
                                                                                                                                  
                                                                                                                                  
                   F. "RIGHT BREAST MASS, NEEDLE LOCALIZATION BIOPSY":                                                            
                                                                                                                                  
                       INVASIVE ADENOCARCINOMA OF THE BREAST.                                                                     
                          HISTOLOGIC TYPE: DUCTAL.                                                                                
                          NOTTINGHAM COMBINED HISTOLOGIC GRADE: 2 OF 3.                                                           
                             TUBULE FORMATION SCORE: 3                                                                            
                             NUCLEAR PLEOMORPHISM SCORE: 2                                                                        
                             MITOTIC RATE SCORE: 1                                                                                
                          GROSS TUMOR SIZE: 2.6 X 0.7 X 0.7 CM.                                                                   
                          SIZE OF INVASIVE COMPONENT: 2.4 CM.                                                                     
                          LYMPHATIC/VASCULAR INVASION: ABSENT.                                                                    
                          MULTIFOCAL TUMOR: ABSENT.                                                                               
                                                                                                                                  
                       IN-SITU CARCINOMA: PRESENT.                                                                                
                          TYPE OF IN-SITU CARCINOMA: SOLID.                                                                       
                          NUCLEAR GRADE OF IN-SITU CARCINOMA: 2 OF 3.                                                             
                          NECROSIS: ABSENT.                                                                                       
                          DCIS EXTENDING OUTSIDE INVASIVE TUMOR MASS: PRESENT.                                                    
                          SIZE OF IN-SITU CARCINOMA: NOT APPLICABLE.                                                              
                                                                                                                                  
                       STATUS OF NON-NEOPLASTIC BREAST TISSUE: PRIOR BIOPSY SITE CHANGE,                                          
                       PROLIFERATIVE FIBROCYSTIC CHANGES.                                                                         
                       SIZE OF BIOPSY: 7.7 X 1.6 X 6.6 CM.                                                                        
                       MICROCALCIFICATIONS: ABSENT.                                                                               
                       SURGICAL MARGIN STATUS: CLOSE, INVASIVE CARCINOMA IS LESS THAN 0.3 MM FROM                                 
                       THE LATERAL (BLACK INKED) MARGIN.                                                                          
                       DCIS IS CLOSE (LESS THAN 0.2 CM) FROM THE LATERAL (BLACK INKED) MARGIN.                                    
                       PLEASE REFER TO NEW LATERAL MARGIN BELOW (SPECIMEN J).                                                     
                                                                                                                                  
                       ESTROGEN/PROGESTERONE RECEPTOR, CELL CYCLE, AND HER2/NEU ANALYSIS:                                         
                       PENDING.                                                                                                   
                          PARAFFIN BLOCK NUMBER: F15.                                                                             
                          RESULTS WILL BE ISSUED IN SEPARATE REPORT FROM THE IMAGE CYTOMETRY LAB                                  
                                                                                                                                  
                                                                                                                                  
                   G. "RIGHT BREAST MASS, INFERIOR MARGIN":                                                                       
                                                                                                                                  
                       NO CARCINOMA IDENTIFIED.                                                                                   
                                                                                                                                  
                                                                                                                                  
                   H. "RIGHT BREAST, SUPERIOR MARGIN":                                                                            
                       NO CARCINOMA IDENTIFIED.                                                                                   
                                                                                                                                  
                                                                                                                                  
                   I. "RIGHT BREAST, INFERIOR MARGIN":                                                                            
                                                                                                                                  
                       NO CARCINOMA IDENTIFIED.                                                                                   
                                                                                                                                  
                                                                                                                                  
                   J. "RIGHT BREAST, LATERAL MARGIN":                                                                             
                                                                                                                                  
                       NO CARCINOMA IDENTIFIED.