Difference between revisions of "HCLS/ClinicalObservationsInteroperability"

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(Patient Recruitment)
(Patient Recruitment)
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* Eureka -  
 
* Eureka -  
 
* Linked2Safety -  
 
* Linked2Safety -  
* EHR4CR -
+
* [http://www.ehr4cr.eu/ <span title="Electronic Health Record for Clinical Research">EHR4CR</span>] -
  
 
= Related Work =
 
= Related Work =

Revision as of 16:03, 24 January 2013

COI Task Force

tasks

  • terminfo current - define equivalences and normal forms for clinical data expressible in either the information model (e.g. HL7/RIM) and terminology model (e.g. SNOMED-CT)
  • HL7/RIM current - OWL representation of the RIM's MIF.
  • CDISC current - leverage Roche's investment in RDF representations of CDISC standards.
  • EMR + Clinical Trials completed 2010 - express clinical trial protocols as SPARQL queries and execute them on clinical RDBs.

Use Cases

Patient Recruitment

  • EMR + Clinical Trials - A researcher inteface presented inputs for age, sex, medication/dosage inclusion and exclusion critera. The medications were expanded to include all drugs in their class. The interface produced a SPARQL query in a clinical research ontology. It was transformed to a query in a clinical care ontology, which was then transformed to a SQL query for a speclfic clinical care SQL schema.
  • Eureka -
  • Linked2Safety -
  • EHR4CR -

Related Work

European Initiatives

(IMI) Innovative Medicines Initiative
pre-competetive public/private parnership between EU and pharma (via EFPIA) running 2007-2017. Two foci:
  1. Efficacy Evaluation (for lung, prostate, ovarian, breast and colon cancers)
    PREDECT
    models for cancer treatments.
    ONCOTRACK
    biomarkers and response to cancer treatments.
    QUIC-CONCEPT
    biomarkers for cancer treatments.
    RAPP-ID
    point-of-care microbe detection, working with Q-Linea.
    SAFE-T
    kidney, liver and vascular drug safety/covigilance, working with EMA and FDA.
    BTCure
    cures for and intervention against rheumatoid arthritis.
  2. Knowledge Management for pharma research
    EHR4CR
    integration of EHRs for clincal research, use cases: e.g. patient recruitment, adverse event detection
    contact: Pierre-Yves Lastic, Sanofi
    DDMoRe
    modeling and simulation standards.
    OPEN-PHACTS
    SemWeb-based open-access drug discovery platform.
    contact: Egon Willighagen

related: (Pierre's overview)
HealthGrid
Grid for biomedical
p-medicine
VPH, personalized medicine (FP7-ICT-IP-270089, 2011-2015)
contact: Stenzhorn, Holger, Benjamin Jefferys
twobias
Bio-threat surveillance
DISCIPULUS
ICT requirements for Digital VPH Patient
(FP7/2007-2013)
EUROCAT
registries for logging births and congenital birth defects. Indexes about 1/4 of European births.
Granatum - think tank for biomedical progress
(EU funded project GRANATUM Biomedical Semantic Model)
SemanticHeathNet (who)
IT Future of Medicine (ITFoM) (integration blurb)

US Initiatives

Indivo
PCHRs in XML, working with Dossia
Dossia
PHR for employees
I2B2

HITECH Act

funding sources: