Synthetic peptide 41 54 human bcl-2 protein peptide corr. to 20 34 the 26 kDa human bcl-2 protein Synthetic peptide 201 216 the bcl-x protein. Synthetic peptide corr to 41 54 human bcl-2 synthetic peptide sequence comprising 51 54 bcl-2 protein. synthetic peptide corr. to GAAPAPG IFSSQPG, 41 54 human bcl-2 protein synthetic peptide 7 18 , Cys-QSNRE LVVDFLS, of human Bcl-X protein calmodulin-binding domain of myosin lightchain kinase fused to 42 142 chicken Bcl-X A synthetic peptide 41 54 human Bcl-2, GAAPAPG IFSSQPG-Cys synthetic peptide corr. to 61 76 mouse Bcl-2Cys-VHREMAAR TSPLRPLV peptide corr. to 20 34 human Bcl-2 protein recombinant peptide sequence, 51 54 bcl-2 recombinant 51 54 bcl-2 synthetic peptide corr. to 687 706 , the carboxy terminus of bcl-6of human origin. synthetic peptide corr. to 41 54 the bcl-2 protein Human Bcl-w synthetic peptide ( 16 29 )with an additional cysteine residue Human Bcl-2 synthetic peptide ( 41 54 ) with an additional cysteine residue Human Bcl-2 synthetic peptide ( 16 29 )with an additional cysteine residue 61 76 the human Bcl-2 peptide coupled to KLH 41 54 the Bcl-2 protein 41 54 , GAAPAPG IFSSQPG, of human bcl-2a protein 41 54 bcl-2 protein synthetic peptide corr. to 41 54 bcl-2 protein synthetic peptide corr. to 3 14 human bcl-xl synthetic peptide corr. to 3 14 human bcl-xl synthetic peptide corr. to 61 76 mouse bcl-2 synthetic peptide corr. to 5 19 human bcl-10, N-term 61 76 the mouse bcl-2 protein. 41 54 the mouse bcl-2alpha protein. 3 14 the human bcl-xL protein. 150 169 the Bcl-X protein aa. 201 213 the bcl-X protein aa. 20 34 the bcl-2 protein 120 133 , AYQSFE QDTFVEL spanning the epitope created as a result of alternate splicing. 298 312 [TKYLKENF SPWIQQH] of the human BCL peptide 71 83 [SWPCRNS QSSEKA] of the human BCL peptide fragment corresponding to 49 179 human bcl-2 protein synthetic peptide corr. to 68 86 mouse bcl-2, highly conserved between mouse and rat synthetic peptide corr. to 68 86 mouse bcl-2, highly conserved between mouse and rat synthetic peptide of 41 54 aa sequence of human Bcl-2 synthetic peptide corr. to 120 133 Bcl-X_S synthetic peptide corr. to 41 54 Bcl-2 synthetic peptide corresponding to 41 54 the Bcl-2 protein, conjugated to thyroglobulin calmodulin-binding domain of myosin light chain kinase fused to 42 142 chicken Bcl-X. This sequence shares 75% homology with amino acids 46-146 of human, mouse and rat Bcl-X. synthetic peptide corresponding to 2 20 , N terminal of human Bcl-X synthetic peptide corresponding to 3 14 ,shared by murine and human Bcl-X_L,conj. to KLH synthetic peptide corresponding to 61 76 mouse Bcl-2, conj. to KLH aa. 41 54 GAAPAPG IFSSQPG of human Bcl-2 aa. 41 54 GAAPAPG IFSSQPG of mouse Bcl-2 aa. 42 142 chickenBcl-X; recognizes both Bcl-XL and Bcl-XS synthetic peptide corr. to 41 54 the human Bcl-2 protein 61 76 amino acid sequence of murine Bcl-2, conjugated to KLH synthetic peptide corr. to 41 54 (GAAPAPG IFSSQPG) of the human Bcl-2 protein; not conserved between human and mouse N-terminal peptide, 3 14 , common to human and mouse Bcl-XL and Bcl-XS synthetic peptide containing 61 76 human Bcl-2 protein (differs from mouse) synthetic peptide corr. to 41 54 (GAAPAPG IFSSQPG) of the human Bcl-2 protein; not conserved between human and mouse synthetic peptide corr. to 46 66 the human Bcl-X protein; this region lacks a homolog with other membbers of the Bcl-2 family synthetic peptide corr. to 68 86 the mouse Bcl-2 protein, highly conserved between rat and mouse synthetic peptide corr. to 41 54 (GAAPAPG IFSSQPG) of the human Bcl-2 protein; not conserved between human and mouse synthetic peptide containing 61 76 human Bcl-2 protein (differs from mouse) synthetic peptide corr. to 68 86 the mouse Bcl-2 protein, highly conserved between rat and mouse synthetic peptide corr. to 41 54 (GAAPAPG IFSSQPG) of the human Bcl-2 protein; not conserved between human and mouse synthetic peptide corr. to 41 54 (GAAPAPG IFSSQPG) of the human Bcl-2 protein; not conserved between human and mouse; second antibody is a control, unknown specificity synthetic peptide corr. to 46 66 the human Bcl-X protein; this region lacks a homolog with other membbers of the Bcl-2 N-terminal peptide, 3 14 , common to human and mouse Bcl-XL and Bcl-XS Synthetic peptide corr. to 61 76 the mouse Bcl-2 sequence synthetic peptide corr. to 41 54 the human Bcl-2 sequence Synthetic peptide corr. to 3 14 the human Bcl-xL sequence; this epitope also present in Bcl-xS recombinant mouse Bcl-2, 1 208 , lacking the C-term mitochondrial targeting sequence KLH coupled, synthetic peptide corr. to 32 51 human and mouse Bcl-w KLH coupled, synthetic peptide corr. to 4 22 human and mouse Bcl-2 purified, recombinant human Bcl-w 1 172 with 6 histidines at the C-terminus purified, E. Coli-derived recombinant mouse Bcl-2 related protein A1, 1 152 18 233 rat Bcl-XL including membrane localization hydrphobic tail 18 233 rat Bcl-XL 49 179 human Bcl-2 18 233 human Bcl-XL synthetic peptide of the LDL receptor binding region, 140 159 human apolipoprotein E2, AA 154 172 (Arg158-Cys) synthetic peptide corresponding to partial amino acid 109 119 a.a.) of human apolipoprotein E4 154 172 human Apo E2 (Arg158-Cys) human Apo E2 (Arg158-Cys) aa. 154 172 a recombinant protein corresponding to 126 191 human apoE a recombinant protein corresponding to 18 317 at the carboxy terminus of human apoE 19 175 human Apo E vicinity of 142 147 vicinity of 243 272 synthetic peptide corresponding to 768 781 human or mouse β-Catenin 769 781 epitope between amino acid 683 781 epitope between amino acid 1 70 epitope between amino acid 70 120 mouse recombinant β-Catenin ( 35 50 ) mouse recombinant β-Catenin( 27 37 ) 683 781 , Cterminally directed β-Catenin 683 781 , Cterminally directed β-Catenin 1 70 at Nterminus of β-Catenin 1 70 at Nterminus of β-Catenin 70 120 in Exon 3 of β-Catenin 70 120 in Exon 3 of β-Catenin 758 771 , in the carboxy terminus of human β-Catenin synthetic peptide (PGDSNQL AWFDTDL) corr. to 768 781 human or mouse beta-catenin, conj. to KLH a 23 kDa protein fragment corresponding to 571 781 mouse β-Catenin mapping to 764 781 carboxy terminus of the humanβ-Catenin a recombinant protein corresponding to 680 781 mapping at the carboxy terminus of human β-Catenin 680 781 mapping at the carboxy terminus of human β-Catenin a peptide corresponding to 768 781 human or mouse β-Catenin 571 781 mouse β-Catenin 571 781 mouse β-Catenin 571 781 mouse β-Catenin 571 781 mouse β-Catenin 29 49 human β-Catenin (consensus GSK3 site) recombinant protein corr. to 2957 3256 mapping at carboxy terminus of human Ki-67 recombinant protein corr. to 2957 3256 mapping at carboxy terminus of human Ki-67 1547 1742 in the tandem repeats section of human Ki-67 270 282 mouse NFkB p65 human peptide, epitope: 363 376 human peptide, epitope: 501 515 human peptide, epitope: 2 17 human peptide, epitope: 363 376 human peptide, epitope: 501 515 human peptide, epitope: 2 17 recombinant protein corr. to 1 447 , full length Human NFκB p52 recombinant protein corr. to 1 447 , full length Human NFκB p52 a recombinant peptide mapping at 1 286 corr. to the amino terminus of Human NFκB p65 a recombinant peptide mapping at 1 286 corr. to the amino terminus of Human NFκB p65 a recombinant peptide mapping corr. to 120 239 at the amino terminus of Human NFκB p50 a recombinant peptide mapping corr. to 120 239 at the amino terminus of Human NFκB p50 mapping corr. to 1 447 , full length Human NFκB p52 mapping corr. to 1 447 , full length Human NFκB p52 mapping corr. to 1 447 , full length Human NFκB p52 recombinant protein corr. to 1 286 at the amino erminus of Human NFκB p65 recombinant protein corr. to 1 286 at the amino erminus of Human NFκB p65 recombinant protein corr. to 1 286 at the amino erminus of Human NFκB p65 recombinant protein corr. to 120 239 at the amino terminus of Human NFκB recombinant protein corr. to 120 239 at the amino terminus of Human NFκB epitope corr. to 350 363 mapping at the NLS region of human NFκB p50 epitope corr. to 338 357 mapping at the C-terminus of human NFκB p50 epitope corr. to 120 239 mapping at the amino terminus of human NFκB p50 epitope corr. to 120 239 mapping at the amino terminus of human NFκB p50 epitope corr. to 298 324 mapping within a conserved epitope of mouse NFκB p50 (identical to human) epitope corr. to 531 550 mapping at the C-terminus of human NFκB p65 epitope corr. to 3 19 mapping within the N-terminus of human NFκB p65 epitope corr. to 4 21 mapping at the N-terminus of mouse NFκB p50 a recombinant peptide mapping at 1 286 corr. to the amino terminus of Human NFκB p65 recombinant protein corr. to 1 447 , full length Human NFκB p52 a recombinant peptide mapping corr. to 120 239 at the amino terminus of Human NFκB p50 mapping corr. to 1 447 , full length Human NFκB p52 recombinant protein corr. to 1 286 at the amino erminus of Human NFκB p65 recombinant protein corr. to 120 239 at the amino terminus of Human NFκB human p65, 12 317 , expressed in E. Coli a 23 residue synthetic peptide corr. to 529 551 human NFκB p65, coupled to KLH; identical to mouse sequence over this range mouse NFκB p50 synthetic peptide corr. to 4 21 , with cysteine (C) residue added and peptide coupled to KLH generated from 18 233 human NFκB generated from 18 233 human NFκB GST-fusion protein corr. to 1 444 human NFκB p52 subunit synthetic peptide (CYNPLGLD GIIYDDFK) contained within 4 19 human NFκB p52 subunit,conj. to KLH KLH conj. synthetic peptide (MAEDDPY LGRPE-C) corr. 1 12 NFκB p50 subunit,with a C-terminal cysteine recombinant protein derived from 164 363 human NF-kB p50 protein peptide comprising IkB Kinase β 743 756 C-terminal, conj. to KLH 931 947 on C-terminal of human NFkB Inducing Kinase (NIK) synthetic peptide corr. to 712 727 human NAK/TBK1 recombinant protein derived from 164 363 human NF-kB p50 protein peptide corresponding to 931 947 human NIK peptide corresponding to GST-RANK intracellular domain, 235 616 a recombinant peptide mapping at 1 286 corr. to the amino terminus of Human NFκB p65 recombinant protein corr. to 1 286 at the amino erminus of Human NFκB p65 recombinant protein corr. to 120 239 at the amino terminus of Human NFκB recombinant protein corr. to 120 239 at the amino terminus of Human NFκB synthetic peptide corr. to 526 539 human NF-kB (p65) protein. peptide corr. to 931 947 human NIK synthetic peptide corr. to 712 727 human NAK/TBK1 ChAT 168 189 ) coupled to Keyhole Limpet Hemocyanin with glutaraldehyde GST fusion protein, corresponding to 227 353 human m1. Epitope located in the 3rd intracellular loop GST fusion protein, corresponding to 225 356 human m2. Epitope located in the 3rd intracellular loop recombinant protein corresponding to 364 474 mapping near the carboxy terminus of alpha2 subunit of the human nicotinic acetylcholine receptor recombinant protein corresponding to 346 445 mapping near the carboxy terminus of alpha3 subunit of the human nicotinic acetylcholine receptor recombinant protein corresponding to 342 474 mapping near the carboxy terminus of alpha4 subunit of the human nicotinic acetylcholine receptor recombinant protein corresponding to 356 456 mapping at the carboxy terminus of the beta 1 subunit of the human nicotinic acetylcholine receptor recombinant protein corresponding to 342 433 mapping at the carboxy terminus of the beta 2 subunit of the human nicotinic acetylcholine receptor peptide analogue of the carboxyl terminal of the nicotinic alpha 5 receptor ( 460 468 ) attached to a carrier protein peptide analogue of the carboxyl terminal of the muscarinic M2 receptor ( 457 466 ) attached to a carrier protein peptide analogue of the carboxyl terminal of the muscarinic M3 receptor ( 580 589 ) attached to a carrier protein peptide analogue of the carboxyl terminal of the nicotinic alpha 3 receptor ( 496 503 ) attached to a carrier protein peptide analogue of the carboxyl terminal of the nicotinic beta 3 receptor ( 450 458 ) attached to a carrier protein peptide analogue of the carboxyl terminal of the nicotinic alpha 3 receptor ( 496 503 ) attached to a carrier protein peptide analogue of the carboxyl terminal of the nicotinic alpha 7 receptor ( 493 502 ) attached to a carrier protein peptide analogue of the carboxyl terminal of the nicotinic alpha 4 receptor ( 620 627 ) attached to a carrier protein peptide analogue of the carboxyl terminal of the muscarinic M1 receptor ( 451 460 ) attached to a carrier protein peptide analogue of the carboxyl terminal of the nicotinic beta 2 receptor ( 493 502 ) attached to a carrier protein peptide analogue of the carboxyl terminal of the muscarinic M1 receptor ( 451 460 ) attached to a carrier protein peptide analogue of the carboxyl terminal of the muscarinic M2 receptor ( 457 466 ) attached to a carrier protein peptide analogue of the carboxyl terminal of the muscarinic M3 receptor ( 580 589 ) attached to a carrier protein peptide analogue of the carboxyl terminal of the muscarinic M4 receptor ( 469 478 ) attached to a carrier protein peptide analogue of the carboxyl terminal of the muscarinic M5 receptor ( 519 531 ) attached to a carrier protein peptide analogue of the carboxyl terminal of the muscarinic M5 receptor ( 519 531 ) attached to a carrier protein Synthetic peptide, M1 451 460 ), covalently attached to a carrier protein Synthetic peptide, M2 457 466 ), covalently attached to a carrier protein Synthetic peptide, M3 580 589 ), covalently attached to a carrier protein Synthetic peptide, M4 469 478 ), covalently attached to a carrier protein Synthetic peptide, M5 519 531 ), covalently attached to a carrier protein part of the i3 intracellular loop of human M1 muscarinic acetylcholine receptor ( 227 353 ) part of the i3 intracellular loop of human M2 muscarinic acetylcholine receptor ( 225 356 ) synthetic peptide corresponding to 568 588 the rat nicotinic AChR α4 protein. GST fusion protein and part of i3 intercellular loop of human m1 muscarinic acetylcholine receptor ( 227 353 ) GST fusion protein and part of i3 intercellular loop of human m2 muscarinic acetylcholine receptor ( 225 356 ) GST fusion protein, corresponding to 227 353 human m1. Epitope located in the 3rd intracellular loop GST fusion protein, corresponding to 225 356 human m2. Epitope located in the 3rd intracellular loop part of the i3 intracellular loop of human M1 muscarinic acetylcholine receptor ( 227 353 ) part of the i3 intracellular loop of human M2 muscarinic acetylcholine receptor ( 225 356 ) fusion protein containing 269 320 from human m1 AChR a 23.3kDa fragment corresponding to 411 609 the human AChE protein epitope corresponding to 475 482 mapping at the carboxy terminus of the alpha 1subunit of the human nicotinic acetylcholine receptor precursor protein fragment corresponding to 332 457 from rat ACHRα epitope corresponding to 446 464 mapping at the carboxy terminus of the α3subunit of human nicotinic acetylcholine receptor precursor epitope corresponding to 460 479 mapping at the carboxy terminus of the α3subunit of human nicotinic acetylcholine receptor precursor epitope corresponding to 483 501 mapping at the carboxy terminus of the β2 subunit of human nicotinic acetylcholine receptor precursor epitope corresponding to 385 404 mapping at the carboxy terminus of the β3 subunit of human nicotinic acetylcholine receptor precursor epitope corresponding to 482 501 mapping at the carboxy terminus of the β subunit of human nicotinic acetylcholine receptor precursor protein fragment corresponding to 62 224 from rat AChR beta epitope corresponding to 498 517 mapping at the carboxy terminus of the δ subunit of human nicotinic acetylcholine receptor precursor epitope corresponding to 474 493 mapping at the carboxy terminus of the ε subunit of human nicotinic acetylcholine receptor precursor epitope corresponding to 500 517 mapping at the carboxy terminus of the γ subunit of human nicotinic acetylcholine receptor precursor epitope corresponding to 450 469 mapping at the carboxy terminus of the α2 subunit of rat nicotinic acetylcholine receptor precursor epitope corresponding to 573 592 mapping at the carboxy terminus of the α4 subunit of rat nicotinic acetylcholine receptor precursor epitope corresponding to 501 520 mapping at the carboxy terminus of the δ subunit of mouse nicotinic acetylcholine receptor precursor epitope corresponding to 475 494 mapping at the carboxy terminus of the ε subunit of mouse nicotinic acetylcholine receptor precursor recombinant protein corresponding to 364 474 mapping near the carboxy terminus of alpha2 subunit of the nicotinic acetylcholine receptor of human origin recombinant protein corresponding to 346 445 mapping near the carboxy terminus of alpha3 subunit of the nicotinic acetylcholine receptor of human origin recombinant protein corresponding to 342 474 mapping near the carboxy terminus of alpha4 subunit of the nicotinic acetylcholine receptor of human origin recombinant protein corresponding to 481 614 mapping at the carboxy terminus of acetylcholine esterase (AchE) of human origin. recombinant protein corresponding to 231 350 mapping within an internal region of muscarinic acetylcholine receptor M1 of human origin recombinant protein corresponding to 211 380 mapping within an internal region of muscarinic acetylcholine receptor M2 of human origin recombinant protein corresponding to 271 480 mapping within an internal region of muscarinic acetylcholine receptor M3 of human origin recombinant protein corresponding to 220 394 mapping within an internal region of muscarinic acetylcholine receptor M4 of human origin recombinant protein corresponding to 230 426 mapping within an internal region of muscarinic acetylcholine receptor M5 of human origin recombinant protein corresponding to 356 456 mapping at the carboxy terminus of the beta 1 subunit of the nicotinic acetylcholine receptor of human origin recombinant protein corresponding to 342 433 mapping at the carboxy terminus of the beta 2 subunit of the nicotinic acetylcholine receptor of human origin 411 609 at the C terminal of human AChE 62 224 near the N terminal of rat nicotinic AChRβ 332 457 at the C terminal of rat nicotinic AChRα peptide corresponding to 362 380 human RAGE peptide corresponding to 42 59 human RAGE synthetic peptide corresponding to 42 59 human RAGE synthetic peptide corr. to 42 59 human RAGE Peptide corresponding to 42 59 human RAGE synthetic peptide corr. to 42 59 human RAGE synthetic peptide corr. to 385 399 human RAGE 1 300 mapping at the amino terminus of human RAGE Peptide corresponding to 42 59 human RAGE synthetic peptides corresponding to 2 12 in α-syn synthetic peptides corresponding to 104 119 in α-syn 116 131 the human αsynuclein coupled to diphtheria toxoid with a cysteine residue attached to the N-terminal of the peptide 11 26 the human α,β and γ synuclein protein residue synthetic 116 131
on the C-terminus of human alpha synuclein peptide 116 131 from human alpha-synuclein synthetic peptide corresponding to residues [Cys], 117 131 human α-synuclein Synthetic peptide corresponding to 116 131 humanα-synuclein recombinant protein corresponding to 1 140 representing fulllength human α-synuclein epitope = 121 125 human α-synuclein 116 131 on the C-terminus ofhuman synt. αsynuclein synthetic peptide corresponding to 116 131 C-terminus of human α-synuclein. immunogen = recombinant human α-synuclein, 121 125 116 131 the human synt. α-synucleinprotein, coupled to KLH 123 140 the C-terminal of the cloned rat α-synuclein Human α-synuclein 111 131 coupled to KLH Human α-synuclein 111 131 coupled to KLH 116 131 on the C-terminus ofhuman α-synuclein 116 131 human α-synuclein 108 120 human synthetic α-synuclein 116 131 human syntheticα-synuclein synthetic peptide corresponding to residues [Cys], 117 131 human α-synuclein 116 131 the human αsynuclein coupled to diphtheria toxoid with a cysteine residue attached to the N-terminal of the peptide 123 140 the C-terminal of the cloned rat α-synuclein 116 131 human synthetic α-synuclein epitope = 121 125 human α-synuclein recombinant protein corresponding to 1 140 representing fulllength human α-synuclein 15 123 rat synuclein-1 antibody against Aβ N-terminus ( 1 6 ) used as secondary conjugated antibody synthetic peptide for C-terminal of human Amyloidβ 1 42 ) synthetic peptide for C-terminal of human Amyloidβ 1 43 ) antibody against Aβ 11 28 ) used as secondary conjugated antibody antibody against Aβ N-terminus ( 1 6 ) used as secondary conjugated antibody antibody against Aβ 11 28 ) used as secondary conjugated antibody amyloid beta, juxtamembrane EC domain, 17 24 7 aa, C-terminus
homologous to Ab[ 1 28 ], Ab[12-28] 1 40 /42
homologous to Ab[1-28], Ab[12-28] 8 aa, C-terminal 1 42 17 42 20 40 37 42 synthetic peptide consisting of 8 17 amyloid beta protein/ amyloid A4, with additional C-terminal cysteine coupled to KLH synthetic peptide for C-terminal of human Amyloidβ 1 40 ) synthetic peptide corr. to 17 26 Amyloid β peptide synthetic peptide corr. to 1 14 human Amyloid β protein synthetic 1 40 human β amyloid synthetic 1 40 β amyloid coupled to human Thyroglobulin Aβb[ 1 40 ] coupled to hTg 15 30 1 14 , N-terminal 1 17 1 16 1 16 synthetic Ab[ 1 40 ] synthetic 1 40 synthetic Amyloid β 1 40 protein synthetic peptide corr. to 1 16 Amyloid β peptide N-terminal: Epitope mapping corr. to amino acid 4 10 human Aβ-peptide C-terminal epitope mapping corr. to amino acid residue 31 40 human Aβ peptide C-terminal epitope mapping corr. to amino acid 33 42 human Aβ peptide Aβ 1 42 peptide at the C-terminus synthetic Abeta peptide [ 1 40 ] without additional carrier 8 17 , synthetic 1 40 synthetic C terminal 8 aa peptide from human beta 1 40 synthetic beta- 1 40 conj. to BSA synthetic C terminal 8 aa peptide from human beta 1 42 Amyloid Beta 1 40 ) Amyloid Beta 1 40 ) Amyloid Beta 1 40 ) Amyloid Beta 1 40 ) Amyloid Beta 1 40 ) synthetic 1 40 β amyloid coupled to human Thyroglobulin Aβb[ 1 40 ] coupled to hTg synthetic peptide of 1 10 mature human amyloidA4/amyloid β; same as aa 653-662 of human APP synthetic peptide of 8 17 mature amyloidA4/amyloid β; same as aa 660-669 of human APP synthetic 12 28 , conjugated to BSA synthetic 25 35 , conjugated to BSA 15 30 synthetic peptide [ 1 40 ] synthetic peptide [ 1 42 ] synthetic peptide [ 1 43 ] 672 714 Amyloid A4 synthetic peptide corr. to 17 24 β-amyloid, conjugated to KLH. Epitope at aa 1-12 synthetic peptide corr. to 1 17 β-amyloid, with Glu substituted at position 11, conjugated to KLH. Epitope at aa 1-12 synthetic peptide of approximately 7 10 amino acid residues at the C-terminus of Aβ 43. synthetic β-amyloid peptide 1 40 ) conjugated to KLH. Epitope at aa 1-12 β-Amyloid [ 1 40 ], corr. to APP(672-711), conj. to BSA amino acid residue 32 40 beta Amyloid β 1-40 peptide, conj. to KLH amino acid residue 33 42 beta Amyloid β 1-42 peptide, conj. to KLH 30 aa from bAp[ 1 43 ] b/A4 1 28 amino acid residue 17 24 beta Amyloid peptide amino acid residue 17 24 beta Amyloid peptide amino acid residue 17 24 beta Amyloid peptide amino acid residue 1 17 beta Amyloid peptide amino acid residue 1 17 beta Amyloid peptide amino acid residue 1 17 beta Amyloid peptide synthetic peptide fragment coupled to a carrier protein;epitope at 1 5 full length amyloid beta 1 42 ; epitope at aa 1-11 amyloid-beta 1 7 amyloid-beta 15 24 amyloid beta 3 9 amyloid beta 7 1 )-42; epitope = aa 11-26 4 10 β-Amyloid central domain 13 28 Amyloid-beta 653 662 from human amyloid A4 precursor protein and amino acids 1-10 from Abeta (completely conserved in rabbit, pig, bovine,guinea pig, and chicken) 737 751 (G Y E N P T Y K F F E Q M Q N) from human amyloid A4 precursor protein; sequence completely conserved in monkey and chicken 44 63 aa of N-Terminus human APP, Cys+ 756 770 , C-Terminus synthetic peptide corresponding to ( 653 662 ) of human APP A4, or aa 1-10 of the 4k Aβ peptide generated by β- and γ-secretases synthetic peptide corresponding to C-terminal ( 737 751 ) of APP A4, or aa 85-99 of the C99 fragment generated by β-secretase 681 695 synthetic 15-aa peptide near the extracellular, KPI-region 301 316 aa) of human APP770 a synthetic 20-aa peptide near the extracellular, N-terminus 44 63 aa) of human APP695 21-aa peptide within the extracellular 18 38 aa), N-terminus of human APP695 a synthetic 15-aa peptide near the C-terminus of human APP695 606 620 aa) 643 695 synthetic 44 63 , N-terminal synthetic 681 695 , C-terminal synthetic 339 348 (C-terminal) of human APP, frameshift mutant synthetic human APP, 44 63 , N-terminal synthetic human APP, 681 695 , C-terminal synthetic human APP, 339 348 frameshift mutant, mid portn N-terminal 1 100 secreted form of APP synthetic peptide corresponding to aa 681 695 C terminus of APP synthetic peptide corresponding to aa 44 63 N terminus of human APP synthetic peptide corresponding to aa 339 348 frameshift mutant APP 44 63 on the N-terminus of APP synthetic human APP, 681 695 , C-terminal synthetic 20-aa peptide near the extracellular, N-terminus 44 63 aa) of human APP695 N-terminal epitope ( 60 100 ) on the pre-A4 molecule. synthetic Alz 90 ( 511 608 Alzheimer precursor protein A4) carboxyl fragment APP 643 695 /Jonas synthetic peptide, C-terminal region ( 751 770 ) of APP, conjugated to maleimide-activated KLH. synthetic peptide, 681 695 human APP synthetic peptide, 339 348 on mid portion of APP Frameshift Mutant synthetic peptide, 643 653 at the C-terminus of APLP1, coupled to KLH synthetic peptide, 643 653 at the C-terminus of APLP1, coupled to KLH N-terminal region ( 44 63 ) of APP C-terminal region ( 681 695 ) of APP Frameshift Mutant( 339 348 ) peptide to the N-terminal region ( 44 63 ) of APP APP ( 99 126 ) APP ( 99 126 )
KPI domain synthetic peptide ( 339 348 ) of APP Frameshift Mutant, C-terminal region carboxyl fragment of APP 643 695 /
Jonas synthetic 511 608 APP pre A4-695 44 63 on the N-terminus of APP synthetic peptide of 44 63 on the N-terminus of APP synthetic peptide of 681 695 on the C-terminal of APP synthetic peptide of 339 348 the C-terminal APP frameshift mutant 44 63 339 348 synthetic peptide, 1 16 A beta
(DAEFRHDS-
GYEVHHQK) synthetic peptide, 653 662 APP A4, or 1 to 10 of the 4K Aβ peptide generated by β- and γ-secretases synthetic peptide, 737 751 APP A4, or 85-99 of the C99 fragment generated by β-secretase synthetic peptide, C-terminal region ( 751 770 ) of APP, conjugated to maleimide-activated KLH. synthetic peptide, 681 695 human APP synthetic peptide, 339 348 on mid portion of APP Frameshift Mutant peptide corr. to 653 652 human APP or 1-10 of the 4 kDa Aβ peptide. Peptide sequence identical in rabbit, pig, bovine, guinea pig and chicken peptide corr. to 737 751 human APP or 85-99 of the C99 fragment generated by β-secretase cleavage. Peptide sequence identical in monkey, mouse, rat and chicken synthetic peptide, 653 662 APP A4, or 1 to 10 of the 4K Aβ peptide generated by β- and γ-secretases synthetic peptide, 737 751 APP A4, or 85-99 of the C99 fragment generated by β-secretase synthetic peptide, 653 662 APP A4, or 1 to 10 of the 4K Aβ peptide generated by β- and γ-secretases synthetic peptide, 737 751 APP A4, or 85-99 of the C99 fragment generated by β-secretase synthetic peptide of 511 608 from APP A4(695) carboxy fragment APP 643 695 /Jonas 44 63 on the N-terminus of APP synthetic, 339 348 on the mid-portion of human APP Frameshift Mutant synthetic peptide, 737 751 human APP synthetic peptide, 653 662 human APP purified synthetic peptide, 681 695 at C terminus of human APP purified synthetic peptide, 339 348 at C terminus of APP frameshift mutant synthetic peptide corr. to 676 695 on C-terminal of APP₆₉₅ Kunitz Protease Inhibitor domain ( 301 315 ) of APP₇₇₀ synthetic, 46 60 the N terminus of APP₆₉₅ amino acid residue 17 24 beta Amyloid peptide amino acid residue 17 24 beta Amyloid peptide amino acid residue 17 24 beta Amyloid peptide amino acid residue 1 17 beta Amyloid peptide amino acid residue 1 17 beta Amyloid peptide amino acid residue 1 17 beta Amyloid peptide synthetic peptide, 18 38 , of Human APP₆₉₅ Human APP synthetic peptide ( 653 662 ), identical to human amyloid β peptide (aa. 1-10) synthetic peptide, C terminal ( 737 751 ) of human APP, same as human C99 fragment (aa. 85-99) peptide corr. to 348 464 human APP-BP1 N-terminus of Amyloidβ, 595 611 APP 444 592 human APP 444 592 APP 19 35 mouse Bad,
coupled to KLH 1 204 GST-mouse BAD 1 204 GST-mouse BAD 106 119
synthetic mouse Bad.
coupled to KLH synthetic phospho-
14 3 -3 binding motif
containing peptide 131 141 mouse Bad, synthetic KLH coupled synthetic peptide corr. to 1 21 human Bad 1 168 , full length
himan Bad 1 168 , full length
himan Bad synthetic peptide corr. to 1 21 human Bad 107 117 mouse Bad, synthetic 19 35 mouse
Bad, coupled to KLH 39 198 aa of
mouse Bad 39 198 aa of
mouse Bad 39 198 aa of
mouse Bad 39 198 aa of
mouse Bad 131 141
of murine Bad [RSRHS(pS)
YPAGT]
107 117
of murine Bad (SPFRGRS
R[pS]APPN), 128 140
of murine Bad (METRSRH
[pS]SYPAG), 05 117
of murine Bad synthetic peptide, corr. to 43 61 human Bax synthetic peptide, corr. to 3 16 human Bax synthetic peptide, corresponding to 3 16 mouse Bax, not shared by rat or human synthetic peptide, corr. to 3 16 rat Bax, not shared by mouse or human synthetic peptide, conj. to KLH, corr. to 12 24 human Bax ( 3 16 ) 150 165 106 119 mouse Bad Synthetic peptide
( 150 165 ) synthetic peptide corresponding to 12 24 human Bax protein; sequence is shared by rat and mouse KLH conj. synthetic peptide corresponding to 1 21 human Bax protein synthetic peptide 150 165 ) of human bax protein, coupled to thyroglobulin synthetic peptide 150 165 ) of human bax protein, coupled to thyroglobulin synthetic peptide 150 165 ) of human bax protein, coupled to thyroglobulin synthetic peptide 150 165 ) of human bax protein, coupled to thyroglobulin 44 62 (ELALDPVP- QDASTKKLSEC), coupled to KLH synthetic peptide corresponding to 3 16 mouse bax synthetic peptide corresponding to 8 16 mouse bax synthetic peptide corresponding to
12 24 human bax peptide corresponding to 98 117 human bax 150 165 the human bax protein synthetic peptide corresponds to 43 61 the mouseBax-α synthetic peptide corresponds to 3 16 human Bax. This aa sequence not shared by mouse or rat Bax synthetic peptide corresponds to 3 16 human Bax. This aa sequence not shared by mouse or rat Bax Human Bax synthetic peptide corresponding to 44 62 Synthetic peptide corresponding to
3 16 human bax Synthetic peptide corresponding to
12 24 human bax Synthetic peptide corresponding to
3 16 human bax Synthetic peptide corresponding to
12 24 human bax synthetic peptide, 3 16 (Cys-GSGEQPRGGG-
PTSS) of human bax synthetic peptide, 3 16 (Cys-GSGEQPRGGG-
PTSS) of mouse bax synthetic peptide, 3 16 (Cys-GSGEQPRGGG-
PTSS) of rat bax synthetic pep., 12 24 (Cys-GPTSSEQIMK-
TGA) of human bax synthetic peptide 3 16 (Cys-GSGEQPR GGGPTSS) of human bax protein synthetic peptide 3 16 (Cys-GSGEQLG SGGPTSS) of mouse bax protein, not shared by human or rat synthetic peptide 3 16 (Cys-GSGEQLG GGGPTSS) of rat bax protein, not shared by human or mouse Synthetic peptide corresponding to
3 16 human bax synthetic peptide corresponding to
8 16 mouse bax Synthetic peptide corresponding to 12 24 human bax peptide corresponding to 98 117 human bax. amino acid 150 165 the
human bax protein 337 351 human MAP-1 (which associates with the proapoptotic Bax) synthetic peptide corresponding to aa
43 61 human Bax synthetic peptide corresponding to aa
43 61 mouse Bax N-terminal peptide sequence ( 12 24 ) Synthetic peptide corr. to 3 16 the mouse Bax sequence Synthetic peptide corr. to 12 24 the human Bax sequence Synthetic peptide corr. to 3 16 the human Bax sequence Synthetic peptide corresponding to
12 33 human bax N terminal peptide seq. ( 12 24 ) common to human, mouse and rat synthetic peptide corresponding to aa
43 61 mouse bax 1 171 ; all but the carboxy terminal 21
aa of mouse Bax 1 171 ; all but the carboxy terminal 21 aa of mouse Bax 3 16 human Bax protein 8 16 murine Bax protein synthetic peptide corresponding to aa
43 61 human Bax. synthetic peptide corresponding to 43 61 human Bax. N-terminal region of human Bax (Bax α, 11 30 with C-terminally added lysine) within 12 24 , shared
by Bax from human,
rat and mouse synthetic peptide corresponding to aa
3 16 human Bax synthetic peptide corresponding to aa
3 16 mouse Bax peptide corresponding to 3 16 near the
N-terminus of mouse bax peptide corresponding to 3 16 near the N-terminus of human bax peptide corresponding to 12 24 located nearthe N-terminus, common to human, mouse and rat human Bax synthetic peptide ( 44 62 ) 55 178
human Bax-α 3 16 mouse Bax Trevigen
Cat# 2281MC
12 24 human Bax 3 16 human Bax synthetic peptide corr. to 3 16 Bax protein synthetic peptide corresponding to
1 21 human Bax KLH conj. peptide corresponding to 3 16 near theN-terminus of human Bax KLH conj. peptide corresponding to 3 16 near theN-terminus of human Bax KLH conj. peptide corresponding to 3 16 near theN-terminus of human Bax KLH conj. peptide corresponding to 12 24 near theN-terminus a synthetic peptide corr. to aa. 485 501 at the c-terminus of BACE1, coupled to KLH 44 59 human BACE 485 501 , (CLRQQHDD FADDISLLK) of human BACE a synthetic peptide corr. to 496 511 near the C-terminal of human BACE2 a synthetic peptide corr. to 44 59 near the N-terminal of human BACE2 synthetic peptide, 44 59 human BACE2, N terminal synthetic peptide, 496 511 human BACE2, C terminal peptide corresponding to 485 501 near the C-terminal of human BACE synthetic peptide, CLRQQHDD FADDISLLK, 458 501 Human BACE synthetic peptide, 485 501 Human BACE synthetic peptide, 441 457 Human BACE2 synthetic peptide, 485 501 human β-secretase 1 synthetic peptide, 496 511 human β-secretase 2 synthetic peptide, 44 59 human β-secretase 2 synthetic peptide, 26 45 human β-secretase 1 synthetic peptide, 46 65 human β-secretase 1 a synthetic peptide corr. to aa. 26 45 human BACE a synthetic peptide corr. to aa. 46 65 human BACE a synthetic peptide corr. to aa. 487 501 human BACE a synthetic peptide corr. to aa. 131 142 human BACE2 a synthetic peptide corr. to aa. 131 142 human BACE2 a synthetic peptide corr. to aa. 485 501 at the c-terminus of BACE1, coupled to KLH synthetic peptide corr. to 496 511 (C-term) of human BACE2 synthetic peptide corr. to 44 59 (N-term) of human BACE2 synthetic peptide, 485 501 human BACE, C terminal synthetic peptide, CLRQQHDD FADDISLLK, 458 501 Human BACE synthetic peptide, CLRQQHDD FADDISLLK, 458 501 Human BACE synthetic peptide, 485 501 Human BACE synthetic peptide, corr. to 441 457 human BACE2 synthetic peptide, corr. to 503 518 human BACE2 synthetic peptide, 122 131 Human BACE synthetic peptide, corr. to 496 511 human BACE2 synthetic peptide, corr. to 44 59 human BACE2 14 aa peptide of human APP 590 603
Acetyl-EISEVKM DA EFR D-amide 14aa peptide of human APP 590 603
Acetyl-EISEVNL DA EFR D-amide synthetic peptide, 122 131 human β-secretase 1 485 501 BACE synthetic peptide corr. to 458 501 BACE synthetic peptide, 503 518 Human BACE2 synthetic peptide, 122 131 Human BACE synthetic peptide, 496 511 Human BACE2 synthetic peptide, 44 59 Human BACE2 a synthetic peptide corr. to 44 59 near the N-terminal of human BACE2 a synthetic peptide corr. to 496 511 near the C-terminal of human BACE2 485 501 , (CLRQQHDDFADDISLLK) of human BACE a synthetic peptide corr. to 44 59 near the N-terminal of human BACE2 a synthetic peptide corr. to 496 511 near the C-terminal of human BACE2 a synthetic peptide corr. to 485 501 near the C-terminal of human BACE purified, NS0-derived recombinant human BACE-1 ectodomain ( 22 460 ) purified, NS0-derived recombinant human BACE-1 ectodomain ( 22 460 ) peptide mapping corr. to 419 501 at the carboxy terminus of mouse BACE synthetic peptide corresponding to 44 59 , N-terminal of human BACE2 synthetic peptide corresponding to the C-terminal aa 458 501 human BACE synthetic peptide conjugate to KLH, corr. to 1 10 human CDK5 synthetic peptide conj. to KLH, corr. to 192 209 human p35 Nck5a recombinant protein corresponding to 69 140 mapping near the amino terminus of human p35 1 291 representing full length human Cdk5 1 291 representing full length Cdk5 of human origin. peptide based on the human 33 kDa Cdk5 encoded protein kinase ( 268 283 ) coupled to KLH 15-residue synthetic peptide based on human Cdk5-encoded protein kinase ( 268 283 ) 15 residue synthetic peptide ( 268 283 ) based on human 33 kDa Cdk5 synthetic peptide conjugate to KLH, corr. to 1 10 human CDK5 synthetic peptide conjugated to KLH, corresponding to 192 209 Human p35 Nck5a synthetic peptide conjugated to KLH, corresponding to 192 209 Human p35 Nck5a recombinant protein corresponding to 69 140 mapping near the amino terminus of human p35 1 291 representing full length Cdk5 of human origin 1 291 representing full length Cdk5 of human origin. 15 residue synthetic peptide ( 268 283 ) based on the human 33-kDa Cdk5-encoded protein kinase 306 314 Chromogranin B ( 1 14 ) synthetic GAWK 20 30 ) [Chromogranin B, 420-493], conjugated with BSA Chromogranin C ( 1 14 ) GAWK [Chromogranin B, 440 513 ] 250 301 264 314 264 314 264 314 264 314 264 314 1 15 human chromogranin A, KLH conjugate 1 14 human chromogranin B, KLH conjugate 1 14 human chromogranin C, KLH conjugate Synthetic Chromogranin 420 493 , BSA conj Chromogranin B ( 1 14 ) Chromogranin C ( 1 14 ) GAWK [Chromogranin B, 440 513 ] synthetic GAWK 20 30 ) [Chromogranin B, 420-493], conjugated with BSA Chromogranin A [Tyr^o] 306 314 , rat purified fragment containing aa 116 439 in chromogranin A purified fragment containing aa 116 439 in chromogranin A chromogranin A, 1 15 chromogranin B, 1 14 chromogranin c, 1 14 chromogranin, GAWK 10 20 509 617 the carboxy terminus of human chromogranin A recombinant protein corresponding to 158 457 mapping at the carboxy terminus of chromogranin A of human origin recombinant protein corresponding to 378 677 mapping at the carboxy terminus of chromogranin-B of human origin rat Chromogranin B, 200 389 rat Chromogranin A, 111 220 prokaryotic recomb. protein corr. to 30 163 N-terminus of human COX-2 prokaryotic recomb. protein corr. to 30 163 N-terminus of human COX-2 synthetic peptide corresponding to 272 282 sheep seminal vesicle COX-1 synthetic peptide corr. to C terminal 567 599 mouse/rat COX-2 synthetic peptide corr. to C terminal 570 598 human COX-2 synthetic peptide corr. to 274 288 mouse COX-1 synthetic peptide corr. to 580 590 human COX-2 C-terminal peptide containing 580 598 human Cox-2 recombinant protein corresponding to 63 124 mapping nearthe amino terminus of human Cox-1 recombinant protein corresponding to 50 111 mapping nearthe amino terminus of human Cox-2 sequence 368 604 on C-terminal of rat COX-2 protein sequence 368 604 on C-terminal of rat COX-2 protein 578 596 human COX-2 synthetic peptide from the C terminus of murine/rat COX-2 570 598 synthetic peptide from the C terminus of COX-2 567 599 synthetic peptide from the ovine seminal vesicle COX-1 272 282 synthetic peptide from the murine COX-1 sequence, conjugated to KLH, 274 288 synthetic peptide, from the human Cox-2 sequence, 580 599 synthetic peptide, from the human Cox-2 sequence, 580 599 synthetic peptide from the murine COX-2 sequence, 584 598 synthetic peptide, from the human Cox-2 sequence, 580 599 synthetic peptide from the murine COX-2 sequence, 584 598 prokaryotic recomb. protein corr. to 30 163 the N-terminus of human COX-2 C-terminal peptide containing 580 598 human Cox-2 recombinant protein corresponding to 63 124 mapping nearthe amino terminus of human Cox-1 recombinant protein corresponding to 50 111 mapping nearthe amino terminus of human Cox-2 Prokaryotic recombinant fusion protein corr. to 38 163 the N-terminal domain of human COX-2 C-terminal peptide containing 580 598 human Cox-2 recombinant protein corresponding to 63 124 mapping nearthe amino terminus of human Cox-1 recombinant protein corresponding to 50 111 mapping nearthe amino terminus of human Cox-2 synthetic peptide from the C terminus of murine/rat COX-2 570 598 synthetic peptide from the C terminus of COX-2 567 599 synthetic peptide from the ovine seminal vesicle COX-1 272 282 synthetic peptide from the murine COX-1 sequence, conjugated to KLH, 274 288 synthetic peptide, from the human Cox-2 sequence, 580 599 synthetic peptide, from the human Cox-2 sequence, 580 599 synthetic peptide from the murine COX-2 sequence, 584 598 synthetic peptide, from the human Cox-2 sequence, 580 599 synthetic peptide from the murine COX-2 sequence, 584 598 peptide corr. to 584 598 rat COX-2. Identical to mouse sequence Prokaryotic recombinant fusion protein corr. to 38 163 the N-terminal domain of human COX-2 synthetic peptide corresponding to 272 282 sheep seminal vesicle COX-1 synthetic peptide corr. to C terminal 567 599 mouse/rat COX-2 synthetic peptide corr. to C terminal 570 598 human COX-2 synthetic peptide corr. to 274 288 mouse COX-1 synthetic peptide corr. to 580 590 human COX-2 recombinant, full-length Human ERAB protein (GST Fusion protein), 61 67 recombinant full-length human ERAB protein (GST fused); epitope mapped to 61 67 . recombinant, full-length human ERAB protein (GST fused); epitope is 61 67 human ERAB, 41 57 recombinant, full-length human ERAB protein (GST fused); epitope at 61 67 synthetic peptide corr. to 100 116 human ERAB, N-terminal KLH conj synthetic peptide corr. to 101 119 mouse ERAB Recombinant, full-length human ERAB protein (GST fused); clone��s epitope maps to 61 67 recombinant, full-length Human ERAB protein (GST Fusion protein), 61 67 synthetic peptide conjugated to KLH (N-terminal cysteine; epitope is 100 116 recombinant, full-length human ERAB protein (GST fused); epitope is 61 67 Recombinant, full-length human ERAB protein (GST fused); clone��s epitope maps to 61 67 recombinant, full-length human ERAB protein (GST fused); epitope is 61 67 synthetic peptide conj. to KLH, corresponding to 187 196 human FADD synthetic peptide conj. to KLH, corresponding to 187 196 human FADD recombinant protein corr. to 28 209 mapping at the C terminus of human FADD C-terminal human FADD, 94 208 synthetic peptide [(C)KIDSIED RYPRNLTER] corresponding to 125 140 human FADD human FADD synthetic peptide, 125 140 , with an additional cysteineresidue coupled to KLH mouse FADD synthetic peptide, 125 140 , with an additional cysteineresidue coupled to KLH 16 residue synthetic peptide (C)KIDSIEDR YPRNLTER based on the human FADD ( 125 140 ) with the cysteine (C) residue added and the peptide coupled to KLH recombinant protein corr. to 28 209 mapping at the C terminus of human FADD GST-FADD fusion protein corr. to full length human FADD, 1 208 ; different epitope from clone 1F7 synthetic peptide conj. to KLH, corresponding to 187 196 human FADD 16-residue synthetic peptide based on 125 140 human FADD recombinant protein corr. to 28 209 mapping at the C terminus of human FADD 16 residue synthetic peptide (C)KIDSIEDR YPRNLTER based on the human FADD ( 125 140 ) with the cysteine (C) residue added and the peptide coupled to KLH recombinant protein derived from 94 208 the human FADD Fusion protein containing 269 320 from human m1 AChR synthetic peptide conjugated to KLH, corresponding to 32 45 Human CHRNA4 synthetic peptide conjugated to KLH, corresponding to 34 47 Human CHRNB2 synthetic peptide conjugated to KLH, corresponding to 28 42 Human CHRNA7 synthetic peptide, corresponding to 17 24 human beta Amyloid synthetic peptide, conj. to KLH, corr. to 1 14 human beta Amyloid synthetic peptide, conj. to KLH, corr. to 1 40 beta Amyloid synthetic peptide, conj. to KLH, corr. to 1 17 human β-Amyloid (epitope within aa 3-8) synthetic peptide, conj. to KLH, corr. to 32 40 human β-Amyloid 1-40 synthetic peptide, conj. to KLH, corr. to 33 42 human β-Amyloid 1-42 synthetic peptide, corr. to 1 17 human β-Amyloid synthetic peptide, corr. to 1 16 β-Amyloid sequence corr. to 653 662 human amyloid A4 protein precursor (APP). Identical to that of rabbit, pig, bovine, guinea pig and chicken sequence corr. to 737 751 human amyloid A4 protein precursor (APP) or 85-99 of the 4K Aβ peptide generated by β- and γ-secretases synthetic peptide conjugated to BSA, corr. to 681 695 human APP synthetic peptide conjugated to BSA, corr. to 44 63 human APP synthetic peptide corr. to 339 348 human APP frameshift mutant synthetic peptide corr. to 292 312 the KPI domain of human APP synthetic peptide: RSRHSS YPAGT, corr. to 107 117 mouse Bad synthetic peptide: RSRHS(pS) YPAGT, corr. to 107 117 human Bad synthetic peptide conjugated to KLH, corr. to 65 74 human Bcl2 synthetic peptide: GAAPAPG IFSSQPG-C, corr. to 41 54 human Bcl2 synthetic peptide, 3 14 (Cys-QSNRE LVVDFLS) of human Bcl-X protein; sequence is shared by human and murine bcl-X synthetic peptide, conj. to KLH, corr. to 3 14 human and mouse Bcl-xL. synthetic peptide, 41 54 (GAAPAPG IFSSQPG-Cys), of human bcl-2 protein recomb. Bcl-2 peptide sequence comprising 51 54 Bcl-2 oncoprotein synthetic peptide, corr. to 5 19 human Bcl-10 synthetic peptide sequence comprising 51 54 bcl-2 protein synthetic peptide, 3 14 (Cys-QSNRE LVVDFLS) of human Bcl-X protein recombinant full length protein, human (epitope resides within 122 168 ) Purified recombinant hBcl-w ( 1 172 , accession number U59747) containing six histidines at the C-terminus synthetic peptide, corr. to 120 133 human Bcl xS Synthetic peptide, corr. to 32 45 human beta Catenin, phosphor. at Ser³³ synthetic KLH conj. peptide, corr. to 32 45 human beta Catenin (epitope: DS_p GIHS_p GATTTAPS) recomb. fragment, corr. to 795 953 Human NFkB reducing kinase NIK synthetic peptide, corr. to 931 947 Human NFkB reducing kinase NIK 6xHis-tagged fusion protein, corr. to 105 291 Human IkBα synthetic peptide (DELFPLIF PAEPAQAS), corr. to 2 17 Human NFkB p65 synthetic peptide (TRLVTGAQ RPPDPAP), corr. to 501 515 Human NFkB p65 recomb. fragment, corr. to 433 501 Human NFkB N-terminal: Epitope mapping corr. to amino acid 4 10 human Aβ-peptide C-terminal epitope mapping corr. to amino acid 31 40 human Aβ peptide Aβ 1 42 peptide at the C-terminus N-terminal: Epitope mapping corr. to amino acid 4 10 human Aβ-peptide C-terminal epitope mapping corr. to amino acid 31 40 human Aβ peptide Aβ 1 42 peptide at the C-terminus recombinant protein corresponding to 100 278 mapping at the carboxy terminus of rat FAS-L recombinant protein corr. to 1 335 representing full length human FAS 18-aa synthetic peptide sequience from rat FASL, extracellular domain ( 136 146 ) synthetic peptide: ESLKLRRR VHETDKNC conjugated to KLH, corresponding to 29 44 mouse Fas fusion protein corr. to 21 165 human Fas recomb. fragment, corr. to C terminal 103 281 human fas ligand purified recombinant mouse Fas ligand ( 132 279 ) synthetic peptide conjugated to KLH, corr. to 132 145 human fas ligand Synthetic peptide: (RGQSCNNQ PLNHKVYMR NSKYPEDL), corr. to 196 220 mouse fas ligand Synthetic peptide: (RGQSCNNQ PLNHKVYMR NSKYPEDL), corr. to 196 220 mouse fas ligand Synthetic peptide: (RGQSCNNQ PLNHKVYMR NSKYPEDL), corr. to 196 220 mouse fas ligand Synthetic peptide corr. to 103 281 human fas ligand synthetic peptide representing 321 335 human fas receptor coupled to thyroglobulin peptide cor. to 196 220 mouse Fas Ligand protein peptide cor. to 196 220 mouse Fas Ligand protein. peptide corr. to 196 220 mouse FasL peptide corr. to 196 220 mouse FasL, extracellular immunogen within coding region of the human FasL gene and hasa length of approx. 620 bp located within the region between 30 650 . coding region of the human Fas gene and
has a length of approx. 500 bp located within the regionbetween 500 1000 . synthetic peptide corresponding to 196 220 mouse FasL synthetic peptide corresponding to 196 220 mouse FasL recombinant human soluble FasL, ( 103 281 ) recombinant human soluble FasL, ( 103 281 ) synthetic peptide corr. to 321 335 human fas receptor, coupled to thyroglobulin synthetic peptide corresponding to 29 44 mouse Fas (ESLKLRRR VHETDKNC) coupled to KLH peptide corr. to 261 277 (VSELSLVNF EESQTFFG) of Fas Ligand synthetic peptide (DSENSNFR NEIQSLV) corr. to 321 335 human Fas protein synthetic peptide (QLSLINFE ESKTFFGL) corr. to 261 277 mouse Fas ligand synthetic peptide (MQQPFNYPYP QIYWVDSSAS) corr. to 1 20 human Fas ligand synthetic peptide (KLRRRVH ETDKNC) corr. to 1 20 mouse Fas protein peptide sequence ( 130 146 ) from rat FASL human Fas (epitope at 1 163 ) human Fas (epitope at 1 163 ) peptide cor. to 196 220 mouse Fas Ligand protein peptide cor. to 196 220 mouse Fas Ligand protein. peptide corr. to 196 220 mouse FasL peptide corr. to 196 220 mouse FasL, extracellular epitope on intracellular domain 305 319 ) and extracellular domain (110-120) peptide corresponding to mouse FasL 133 147 peptide cor. to 196 220 mouse Fas Ligand protein peptide cor. to 196 220 mouse Fas Ligand protein. peptide corr. to 196 220 mouse FasL peptide corr. to 196 220 mouse FasL, extracellular synthetic peptide conjugated to KLH, corr. to 132 145 human fas ligand synthetic peptide conjugated to KLH, corresponding to 317 331 Human CD95 purified recombinant mouse Fas ligand ( 132 279 ) synthetic peptide: ESLKLRRR VHETDKNC conjugated to KLH, corresponding to 29 44 mouse Fas fusion protein corr. to 21 165 human Fas recomb. fragment, corr. to C terminal 103 281 human fas ligand Synthetic peptide: (RGQSCNNQ PLNHKVYMR NSKYPEDL), corr. to 196 220 mouse fas ligand Synthetic peptide: (RGQSCNNQ PLNHKVYMR NSKYPEDL), corr. to 196 220 mouse fas ligand Synthetic peptide: (RGQSCNNQ PLNHKVYMR NSKYPEDL), corr. to 196 220 mouse fas ligand Synthetic peptide corr. to 103 281 human fas ligand fusion protein corr. to 21 165 human Fas 18.2 kDa protein fragment corr. to 1 163 human Fas purified CHO-derived rmFas ligand ( 132 279 ) recombinant protein corresponding to 100 278 mapping at the carboxy terminus of rat FAS-L recombinant protein corr. to 1 335 representing full length human FAS 16 residue synthetic peptide (ESLKLRRR VHETDKNC, 29 44 ) of mouse Fas, coupled to KLH human Fas (epitope at 1 163 ) 116 277 human fas ligand 16 residue synthetic peptide (ESLKLRRR VHETDKNC, 29 44 ) based on mouse Fas and coupled to KLH synthetic peptide corr. to intracellular domain ( 104 114 ) of human Fas conj. with KLH synthetic peptide corr. to 22 37 Human FGFR2, conjugated to KLH synthetic peptide corr. to 39 56 Human FGFR4, conjugated to KLH 1 23 synthetic fragment of rat FGF-2 (1-46) 1 24 synthetic fragment of bovine basic FGF (1-46) synthetic peptide conjugated to KLH, corr. to 1 24 Cow FGF2 synthetic peptide: EALEERP AVMTSPLK, conj. to KLH, corr. to 360 373 Human FGFR1 with a C-terminal lysine synthetic peptide: KLPQYPH IGSVKT, conj. to KLH, corr. to 809 821 the cytoplasmic region of Human FGFR2 synthetic peptide: APGREKE ITASPDK, conj. to KLH, corr. to 362 374 Human FGFR2 synthetic peptide: KDLLPPAP PSSGGSRT, conj. to KLH, corr. to 792 806 the cytoplasmic region of Human FGFR3, with N-terminal added lysine synthetic peptide: AEEELVE ADEAGSVK, conj. to KLH, corr. to 359 372 Human FGFR3 1 24 synthetic fragment of bovine FGF-2 1 23 synthetic fragment of rat FGF-2 (1-46) recombinant protein corresponding to 1 208 (full length) hFGF-9 recombinant protein corresponding to 16 140 hFGF-1 10 140 hFGF-2 recomb. protein corr. to 1 208 , (full length) hFGF-9 recombinant FGF basic (epitope within 14 40 ) recombinant bFGF (epitope at 14 40 ) peptide corr. to amino 153 166 the mature form of FGF-3 peptide corr. to 147 153 human bFGF peptide corr. to 40 63 human bFGF synthetic peptide corresponding to 351 366 hFGFR-1 synthetic bovine FGF 1 24 ) synthetic rat basic FGF 1 23 ) recombinant human FGF basic, within 14 40 recombinant FGF basic, within 14 40 peptide corr. to 147 153 human bFGF peptide corr. to 40 63 human bFGF peptide corr. to 351 366 human FGF receptor-1 recombinant FGF basic, within 14 40 recombinant protein corr. to 16 140 representingall but the C-terminal 15 aa. of mature human FGF-1 recombinant protein corr. to 1 208 representingfull length human FGF-9 recombinant protein corr. to 16 140 representing all but the C-terminal 15 aa of mature human FGF-1 recombinant protein corr. to 10 140 representingall but the C-terminal 15 aa of mature human FGF-2 recombinant protein corr. to 22 97 within the intercellular domain of human Flg (FGFR-1) synthetic peptide corr. to 809 821 C-terminal region of human FGFR-2, with N-terminal added lysine, conj to KLH synthetic peptides corr. to 55 68 and 150-162 of FGF-9, conj to KLH synthetic peptides corr. to 1 24 bovine FGF basic synthetic peptide corr. to 360 373 extra cellular region of human FGFR-1 synthetic peptide corr. to 362 374 extra cellular region of human FGFR-2 (Bek), conj to KLH E.coli fusion protein containing 23 325 humanFGF receptor β synthetic peptide corresponding to 119 144 extracellular domain of chicken FGF receptor recombinant human bFGF, epitope located between aa 14 40 human bFGF, epitope located between aa 14 40 synthetic peptide for C-terminal of human β-Amyloid 1 40 synthetic peptide for C-terminal of human β-Amyloid 1 42 Synthetic peptide: RRRVT-phospho SAARRS conjugated to KLH, corr. to 3 13 Pig GFAP 3 13 GFAP phospho. peptides corr. to 3 13 GFAP epitope corresponding to 413 431 mappingat the carboxy terminus of human GFAP epitope corresponding to 2 19 mapping atthe amino terminus of human GFAP recomb. protein corresponding to 1 50 mapping at the amino terminus of human GFAP residues G-E-V-I-K-E-S-K- Q-E-H-K-D-V-M, position: 418 432 GFAP synthetic peptide RARTS_pSFAEPC, corresponding to 16 25 Human GSK3 alpha synthetic peptide RARTSSFAEPC, corresponding to 16 25 Human GSK3 alpha synthetic peptide RRTT_pSFAE, corresponding to 4 12 Human GSK3 beta immunogen = synthetic peptide based on the rat GSK-3β isoform-kinase subdomain XI region ( 335 349 ) rat GSK-3β, 1 160 rat GSK-3β, 1 160 synthetic peptide corr. to 1 30 rat Heme Oxygenase-1 immunizing peptide corresponds to aa 1 30 rat HO-1 synthetic peptide corresponds to amino acid 1 30 derived from the N-terminal domain of rat HO-1 recombinant protein corr. to 184 288 at Carboxy term. of human HO-1 recombinant protein corr. to 293 311 at Carboxy term. of human HO-2 synthetic peptide corresponds to 12 25 human HO-1 protein synthetic peptide corresponds to 246 264 human HO-2 protein peptide corr. to 246 264 human HO-2 synthetic peptide based on the human HO-1 ( 1 30 ) prepared as a four branched multiple antigen peptide aa's 1 261 rat HO-1, not the membrane spanning region, but 7 aa's at the N-terminus and 12 aa's at the C-terminus derived from the expression vector, yielding a 280 aa antigen. aa's 1 261 rat HO-1, not the membrane spanning region, but 7 aa's at the N-terminus and 12 aa's at the C-terminus derived from the expression vector, yielding a 280 aa antigen. synthetic peptide based on the human HO-2 ( 21 50 ) prepared as a four branched multiple antigen peptide. synthetic peptide corresponds to 12 25 )+Cys-NH2 of human HO-1 protein. synthetic peptide corresponds to 246 264 , amidated form, of human HO-2 protein. synthetic peptide corresponding to 12 25 HO-1 synthetic peptide corresponding to 246 265 , amidated form, of human HO-2 protein. a synthetic peptide corresponds to aa [ 12 25 ]+Cys-NH2 of the human HO-1 protein. Totally conserved in the aligned region from pig, rat and mouse synthetic peptide based on the human HO-1 ( 1 30 ) prepared as a four branched multiple antigen peptide aa's 1 261 rat HO-1, not the membranespanning region, but 7 aa's at the N-terminus and 12 aa's at the C-terminus derived from the expression vector, yielding a 280 aa antigen. aa's 1 261 rat HO-1, not the membranespanning region, but 7 aa's at the N-terminus and 12 aa's at the C-terminus derived from the expression vector, yielding a 280 aa antigen. synthetic peptide based on the human HO-2 ( 21 50 ) prepared as a four branched multiple antigen peptide. synthetic peptide corr. to 2 23 rat HO-1 protein; two mismatches with the reported human and rat sequences. synthetic peptide corr. to 2 23 rat HO-1 protein; two mismatches with the reported human and rat sequences. synthetic peptide corr. to 247 258 rat HO-1 protein; one mismatch with human, identical to mouse sequence. synthetic peptide corr. to 2 23 rat HO-1 protein; two mismatches with the reported human and rat sequences. synthetic peptide corr. to 2 23 rat HO-1 protein; two mismatches with the reported human and rat sequences. synthetic peptide corr. to 247 258 rat HO-1 protein; one mismatch with human, identical to mouse sequence. human HO-1 synthetic peptide 1 30 conjugated to KLH protein fragment from 150 286 N term region of human HO-1 protein fragment from 5 115 N-terminal region of human HO-2 synthetic peptide derived from N-terminal 1 30 rat HO-1 recombinant protein corr. to 184 288 at Carboxy term. of human HO-1 recombinant protein corr. to 293 311 at C-terminus of human HO-2 peptide corr. to 2 23 rat HO-1; differs from human, rat by 2 aa peptide corr. to 247 258 rat HO-2; differs from human by 1 aa 30 aa peptide based on human HO-1 1 30 ) 30 residue synthetic peptide based on the human HO-1 1 30 30 residue synthetic peptide based on the human HO-2 21 50 a synthetic peptide corresponds to aa [ 12 25 ]+Cys_-NH2 of the human HO-1 protein. Totally conserved in the aligned region from pig, rat and mouse a synthetic peptide corr. to 246 264 in the amidated form of the human HO-2 protein. Two substitutions in the aligned region from rat, four from rabbit immunizing peptide corresponds to aa 1 30 rat HO-1 synthetic peptide corresponds to amino acid 1 30 derived from the N-terminal domain of rat HO-1 83 90 Htt immunogen at 1171 1177 immunogen at 1844 2131 immunogen at 2703 2911 immunogen at 1171 1177 immunogen at 1171 1177 immunogen at 1171 1177 immunogen at 1171 1177 immunogen at 977 1276 immunogen at 977 1276 immunogen at 1844 2131 immunogen at 1844 2131 immunogen at 2081 2086 immunogen at 2081 2086 immunogen at 2081 2086 immunogen at 2081 2086 immunogen at 2081 2086 immunogen at 2703 2911 immunogen at 2703 2911 immunogen at 2703 2911 amino terminal 1 18 amino terminal 254 271 (epitope within 181 810 human protein) epitope corr. to 2845 3144 mapping at the C-terminus of human Huntingtin Huntingtin fragment from 181 810 as a fusion protein Huntington fragment from 181 810 as a fusion protein Huntingtin fragment from 181 810 as a fusion protein Huntingtin fragment from 2146 2541 as a fusion protein recombinant protein corresponding to 2703 2911 huntingtin recombinant protein corresponding to 1844 2131 huntingtin recombinant protein corresponding to 997 1276 huntingtin recombinant protein corresponding to 1171 1177 huntingtin recombinant protein corresponding to 1844 2131 huntingtin recombinant protein corresponding to 2703 2911 huntingtin recombinant protein corresponding to 997 1276 huntingtin recombinant protein corresponding to 1844 2131 huntingtin recombinant protein corresponding to 2703 2911 huntingtin Huntingtin fusion protein 549 679 , fused to Glutathione S-tranferase 549 679 recombinant protein corr. to 2703 2911 huntingtin recombinant protein corr. to 1844 2131 huntingtin recombinant protein corr. to 997 1276 huntingtin epitope corr. to 2845 3144 mapping at the C-terminus of human Huntingtin Huntingtin fragment from 1247 1646 as a fusion protein Huntingtin fragment from 2146 2541 as a fusion protein Huntingtin fragment from 181 810 as a fusion protein Huntingtin fusion protein 549 679 , fused to Glutathione S-tranferase 314 325 [DGHGQD TSGQLP] of the 40 kDa mouse HAP40 protein peptide corr. to 314 325 the 40 kD mouse HAP40 protein recombinant carboxyl terminal half of the full length human protein (65-kDa); epitope is 750 780 53 352 mapping at the C-terminus of human Endophilin I peptide corr. to amino acid 314 325 mouse HAP40 protein synthetic peptide corr. to 314 325 mouse HAP peptide corresponding to 314 325 the 40 kD mouse HAP40 protein 314 325 [DGHGQD TSGQLP] of the 40 kDa mouse HAP40 25 26 [YRQVSN KLKKR] of the 40 kDa mouse HAP40 peptide corresponding to 314 325 the 40 kD mouse HAP40 protein 314 325 [DGHGQD TSGQLP] of the 40 kDa mouse HAP40 314 325 [DGHGQD TSGQLP] of 40 kDa mouse HAP40 22 amino acid peptide corresponding to 2 23 mouse CBP crosslinked to conalbumin synthetic peptide corresponding to 314 325 mouse HAP rat HAP1-A, 100 289 bovine brain MAP2, (epitope = 997 1332 ) synthetic peptide corr. to 1 28 Human MAP2K1 997 1332 of MAP2 epitope within 997 1332 high MW MAP2 isoforms 1 219 human MAP2B purified, NS0-derived, recombinant human Neurophysin II precursor ( 20 164 ) purified, NS0-derived, recombinant human Neurophysin II precursor ( 20 164 ) epitope at 46 62 hNGF epitope at 46 62 hNGF epitope at 58 68 hNGF 1 20 , n terminal 1 20 , n terminal localized to 46 62 hNGF localized to 46 62 hNGF 1 20 mapping at the amino terminus of the mature form of human NGF 1 20 mapping at the amino terminus of mature mouse NGF a synthetic peptide corresponds to aa [ 12 25 ]+Cys_-NH2 of the human HO-1 protein. Totally conserved in the aligned region from pig, rat and mouse a synthetic peptide corr. to 246 264 in the amidated form of the human HO-2 protein. Two substitutions in the aligned region from rat, four from rabbit recombinant protein corr. to 184 288 at Carboxy term. of human HO-1 recombinant protein corr. to 293 311 at Carboxy term. of human HO-2 NGFR from A875 melanoma cells ( 1 160 ) extracellular fragment from the rat Trk A receptor ( 1 416 ) extracellular fragment from the mouse p75 receptor ( 43 161 ) extracellular fragment from the mouse p75 receptor ( 43 161 ) extracellular fragment from mouse p75
( 43 161 ) extracellular fragment from rat trkA receptor( 1 416 ) recombinant protein corr. to 29 165 within the extracellular domain a.a. region 606 619 synthetic human Trk epitope spans aa seq. 1 160 extracellular domain of NGFR/NTR synthetic peptide corr. to 485 493 human trkA. synthetic peptide corr. to 671 679 human trkA synthetic peptide ( 606 619 ) selected from the C-terminal catalytic domain of human trk NGFR from A875 melonoma cells (epitope within 1 160 , in the extracellular domain of the molecule) 1 160 extracellular domain of NGFR/NTR 777 790 in the C-terminal domain of Trk synthetic peptide containing 322 346 rat TrkA 778 790 in the highly conserved region of the Trk receptors recombinant protein corresponding to aminoacids 29 165 mappping within the extracellular domain of NGFR p75 of human origin. synthetic peptide corr. to C-terminal of rat NGFR p75 ( 407 425 with N-terminally added lysine) synthetic peptide corr. to 777 790 human TrkA TrkA fusion protein, 20 355 human TrkA (epitope in extracellular, N-terminal domain) gel-purified p53-beta-galactosidase fusion protein containing murine p53 from 14 289 (epitope between aa 213 and 217 on human p53) human fusion protein (epitope at 46 55 human p53) beta galactosidase fusion protein corr. to 14 389 human p53 synthetic peptide conjugated to KLH, corresponding to 31 40 human p53 murine p53 protein corr. to 14 289 (epitope at aa 212-217) synthetic peptide: MEEPQS_pDPSVEP, corr. to 1 12 human p53 synthetic peptide: MEEPQSDPSVEP, corr. to 1 12 human p53 recomb. full length human protein (wild type) (epitope at 16 25 ) synthetic peptide: GDPERPEA AGLDQDER, corresponding to 2 17 human p53R2 recomb. full length human protein (epitope at 20 25 ) recomb. full length human protein (epitope at 20 25 ) synthetic peptide, corresponding to 213 217 p53 synthetic peptide, corresponding to 371 380 human p53 synthetic peptide, corresponding to 370 378 human p53 synthetic peptide, corresponding to 370 378 human p53 recombinant fragment, human (epitope at 16 25 ) synthetic peptide, corresponding to 20 25 human p53 synthetic peptide, corresponding to 32 79 human p53 full length protein, corresponding to 88 93 p53 synthetic peptide, MFQRLNK MFVGEVS, corr. to 1 14 human p53DINP1 sequence corr. to the mouse p53 protein surrounding serine 389 (epitope maps within the middle region, 212 217 , of p53) purified recombinant human p53(epitope within 18 30 human p53) Murine p53-β-galactosidase fusion protein (epitope maps within the middle region, 212 217 , of p53) recombinant human wild type p53 protein expressed in E. coli(epitope within the N-terminus, 32 79 , of p53) SV40-transformed mouse B4 cells (epitope maps near the C-terminus, 370 378 , of p53) recombinant human wild type p53 protein expressed in E. coli(epitope within the N-terminus, 37 45 , of p53) recombinant human wild type p53 protein expressed in E. coli(epitope within the N-terminus, 37 45 , of p53) ecombinant human wild type p53 protein expressed in E. coli(epitope within the N-terminus, 11 25 , of p53) SV40 transformed cell line BALB/c SVA31 E7 (epitope between amino acid 88 93 p53) recombinant human wild type p53 protein expressed in E. coli (epitope near N terminus, within 19 26 ) recombinant human wild type p53 protein expressed in E. coli (epitope near N terminus, within 19 26 ) recombinant human wild type p53 protein (epitope maps within the N-terminus, 20 25 ) murine p53-β-galactosidase fusion protein containing 14 289 (epitope maps within the middle region [aa 212-217] of p53) human p53-β-galactosidase fusion protein (epitope maps within 46 55 p53) SV40-transformed mouse B4 cells (epitope mapping near the C-terminal end, 370 378 ) SV40-transformed cell line BALB/c SVA31 E7 (epitope mapping between 88 93 mouse wild-type p53) GST p53 fusion protein containing 1 393 human p53 peptide corr. to 377 387 thehuman p53 sequence with an acetylated lysine at position 382 peptide corr. to 310 322 the mouse p53 sequence with an acetylated lysine at position 317 purified, E.Coli-derived recombinant human p53, 7 393 epitope at 213 217 epitope at 85 109 epitope within 32 79 epitope at 20 25 epitope at 370 378 on the C terminus of mouse p53 epitope in 56 65 , which is located the N-terminus region recombinant p53 peptide (epitope near the N-terminal, between 32 79 aa in the human sequence) recombinant p53 peptide (epitope between the evolutionally conserved Box III and IVregions, approximately 161 220 aa in the human sequence) synthetic peptide based on sequence from C-terminal part of bovine PARP automodification domain ( 509 524 ) synthetic peptide, human (epitope within 43 59 , QRQESKKMP VAGGKANK, of PARP2) epitope found between 216 375 in the DNA binding domain of PARP from purified calf thymus Synthetic peptide: LGELLSTHLLSP- WGAEVKVEPVE corresponding to 471 493 in the automodification domain of bovine PARP Synthetic peptide: SKGPVKEEG- TNKSEKRK corresponding to 509 524 from bovine PARP Synthetic peptide: SKGPVKEEG- TNKSEKRK corresponding to 509 524 in the automodification domain of bovine PARP Synthetic peptide: KQLPGVKSEG- KRKGDEVD corresponding to 197 214 human PARP-1 Synthetic peptide: GVDEVAK- KKSKKEK, corresponding to 215 228 human PARP-1 Synthetic peptide corresponding to 509 524 , automodification domain of bovine PARP-1 raised against the recombinant DNA-binding domain ( 1 232 ) of human PARP-1 raised against the recombinant automodification domain ( 337 573 ) of human PARP-1 491 494 (HPGE) of human minor vault p193 protein/VPARP (PARP-4) 593 599 (FSKVEDY) of human minor vault p193 protein/VPARP (PARP-4) 506 510 (VALGK) of human minor vault p193 protein/VPARP (PARP-4) purified calf thymus PARP-1; epitope for this antibody is found between 216 375 in the DNA-binding domain of PARP-1 synthetic peptide corresponding to 509 524 the bovine PARP protein synthetic peptide corresponding to 197 214 the human PARP protein: KQLPGVKSE- GKRKGDEVD synthetic peptide corresponding to 215 228 the human PARP protein: GVDEVAK- KKSKKEK epitope found between 216 375 in the DNA binding domain of PARP from purified calf thymus based on the sequence from the C-terminal portion of the bovine PARP automodification domain ( 509 524 ) purified poly (ADP-ribose) polymer, chain length of 10 50 units purified calf thymus PARP (epitope between 216 375 in the DNA binding domain) synthetic peptide based on sequence from C-terminal part of the bovine PARP automodification domain ( 509 524 ) synthetic peptide corresponding to 509 524 the bovine PARP protein synthetic peptide corr. to 197 214 the human PARP protein: KQLPGVKSE- GKRKGDEVD synthetic peptide corr. to 215 228 the human PARP protein: GVDEVAK- KKSKKEK 22 219 human PARP purified recombinant peptide corr. to 71 329 murine PARP purified recombinant peptide corr. to 71 329 murine PARP purified recombinant peptide corr. to 71 329 murine PARP 1 20 mapping at the amino terminus of mouse PARP synthetic peptide corr. to aa. 509 524 in the automodification domain of Bovine PARP 1 20 mapping at the amino terminus of mouse PARP 764 1014 mapping at the carboxy terminus of human PARP recombinant protein corr. to a 764 1014 at the C terminus of human PARP epitope is found between 216 375 in the DNA-binding domain of calf thymus PARP synthetic PARP N-terminal peptide corr. to aa. 2 20 human PARP, with C-term. added lysine 15 residue synthetic peptide GVDEVAK- KKSKKEKD based on the human PARP ( 215 229 ) 18 residue synthetic peptide KQLPGVKSE- GKRKGDEVD based on the human PARP ( 197 214 ) synthetic peptide: AESAESGG PPGAQDSAA, corr. to 2 18 mouse ubiquilin synthetic peptide: INAKADVLFI APREPGAVSY corr. to C-terminal 688 708 from human nicastrin synthetic peptide corr. to 688 708 human nicastrin; one aa substitution between human and mouse sequence synthetic peptide corresponds to 2 18 mouse ubiquilin synthetic peptide corr. to aa 689 709 at C-terminus of nicastrin synthetic peptide corr. to aa 62 93 at N-terminus of nicastrin synthetic peptide corresponds to 690 708 mouse nicastrin synthetic peptide corr to C-terminus, 693 709 human nicastrin, conj. to KLH N-terminus 4 15 human PEN-2 synthetic peptide corr. to N-terminus 14 33 human presenilin-1 synthetic peptide corr. to 31 47 human presenilin-2 synthetic peptide corr. to 31 47 human presenilin 2 14 33 aa of N-Terminus, extracellular region synthetic peptide, 14 33 aa of N-Terminus synthetic peptide, 31 47 aa of N-Terminus synthetic peptide corr. to 14 33 N-Terminus 14 33 aa of N-Terminus of presenilin 1 14 33 aa of N-Terminus of S182 protein (exposed to the extracellular region) Synthetic peptide of 31 47 the N-terminus of human PS-2 275 367 human PS1 fused to C-terminus of maltose binding protein 14 23 Human PS1 conjugated to KLH. N-terminal of human PS-1 21 80 fused to GST 263 378 Presenilin-1, loop fusion protein 14 33 N-terminus of Presenilin-1 Synthetic peptide 14 33 the N-terminal presenilin-1 Synthetic peptide 31 47 the N-terminal presenilin-2 synthetic peptide corr. to 324 335 from the C-terminus of human PS2 31 46 N-terminus of mouse PS1 synthetic peptide 303 316 the loop region of mouse PS1 7 24 from the N-terminus of the human PS2 purified E.Coli-derived recombinant human PS-1 NTF ( 1 80 ) purified E.Coli-derived recombinant human PS-2 NTF ( 1 80 ) purified E.Coli-derived recombinant human PS-1 CTF ( 298 407 ) purified E.Coli-derived recombinant human PS-2 CTF ( 322 388 ) purified E.Coli-derived recombinant human PS-1 NTF ( 1 80 ) purified E.Coli-derived recombinant human PS-1 CTF ( 298 407 ) purified E.Coli-derived recombinant human PS-2 CTF ( 322 388 ) purified E.Coli-derived recomb. human PS-1 NTF ( 1 80 ) 14 33 the N terminus of the human PS-1 31 47 the N-terminus of human PS-2 N-terminus peptide ( 14 33 ) of presenilin-1 synthetic peptide corr. to 31 47 Presenilin-2 synthetic peptide corr. to 31 47 Presenilin-2 79 amino acid 1 79 ) from the N-terminus of the human PS1 79 amino acid 1 79 ) from the N-terminus of the human PS1 epitope at PS1, 1 20 loop domain ( 263 407 ) of PS-1 N-terminus ( 2 81 ) of PS-1 loop domain ( 297 356 ) of PS-2 fusion protein, C-terminal ( 263 407 ) fusion protein, C-terminal ( 297 356 ) 454 467 PS1 with glutamate residue added to N terminus to enhance solubility a GST-PS2loop 301 361 ) fusion Protein 454 467 PS1 with glutamate residue added to N terminus to enhance solubility 320 375 human PS1 amino acid peptide corresponding to 301 313 human synaptophysin synthetic synaptophysin ( 254 279 ) sequence synthetic synaptophysin sequence ( 254 279 ), PPD conj. synthetic peptide corr. to human 301 313 , coupled to KLH a recombinant protein corresponding to aminoacids 221 313 mapping at the carboxy terminus of synaptophysin of humanorigin synthetic peptide corr. to human 301 313 , coupled to KLH rat synaptophysin (epitope between 205 307 ) synthetic peptide corr. to 84 104 rat proNGF 83 120 human tau 159 163 194 198 human recomb. tau (epitope between 19 46 ) synthetic peptide: MAEPRQEF EVMEDHAG, corr. to 1 16 human Tau 23 179 human Tau epitope = 1 150 at the amino terminus of human Tau-1 ( 95 108 sequence of tau in a conformation partially dependent on serine in position 101) bovine tau, (epitope within 141 178 the rat sequence) bovine tau (epitope at 83 120 human Tau) bovine tau (epitope near C-terminal region, 404 441 aa., of the rat sequence) (epitope = 395 432 ) synthetic peptide, FSSTEKNC, (corr. to 286 293 390) of full-length TGF-β, including signal peptide; corr. to aa 8-15, of 112, of the mature growth factor GST fusion avian protein, containing chick TGFβR, ( 77 148 ) protein corr. to 1 567 representingfull length human TGFβ-RII protein corr. to 1 567 representingfull length human TGFβ-RII protein corr. to 1 567 representingfull length human TGFβ-RII protein corr. to 1 567 representingfull length human TGFβ-RII mapping at the carboxy terminus of human TGFβ3,( 301 412 ) mapping within extra cellular domain of human TGFβ-RI ( 26 125 ) protein containing chick TGF-β type II receptor 27 85 protein containing chick TGF-β type II receptor 77 148 GST fusion protein containing chick TGF-β type II receptor 27 85 GST fusion protein containing chick TGF-β type II receptor 77 148 E. coli-expressed mature porcine TGF-β1, ( 280 391 ) E. coli-expressed porcine TGF-β1 ( 280 391 ) GST fusion protein containing chick TGF-β type II receptor ( 27 85 ) GST fusion protein containing chick TGF-β type II receptor ( 77 148 ) GST fusion protein, corr. to 27 85 TGFβ R-II GST fusion protein, corresponding to 77 148 TGFβ R-II GST fusion protein, corresponding to 27 85 TGFβ R-II GST fusion protein, corresponding to 77 148 TGFβ R-II recomb. protein encoding 26 176 human CD105 GST fusion protein containing chick TGF-βType II receptor ( 77 148 ) GST fusion protein containing chick TGF-βType II receptor ( 27 85 ) protein corr. to 1 567 , full length human TGFβ-RII protein corr. to 1 567 , full length human TGFβ-RII protein corr. to 1 567 representingfull length human TGFβ-RII protein corr. to 1 567 human TGFβ-RII mapping at the carboxy terminus of human TGFβ3,( 301 412 ) mapping within extra cellular domain of human TGFβ-RI ( 26 125 ) synthetic peptide corr. to C-terminus residues ( 247 266 ) of human ARTS protein, conj. to KLH. synthetic peptide corr. to 561 579 mouse TGF-β activating kinase (TAK1), conj. to KLH. ovalbumin conj. synthetic peptide corr. to 287 302 human NAG1/PTGF-β GST fusion protein of the rat betaglycan extracellular ectodomain ( 31 782 ) expressed in E. coli extracellular fragment generated from sequences from the third exon of mouse p75 ( 43 161 ). recombinant protein corresponding to 149 448 mapping at the carboxy terminus of human α-Tubulin recomb. protein corr. to 210 444 mapping at the C-terminus of human β-Tubulin recombinant protein corresponding to 269 451 mapping at the C-terminus of human γ-Tubulin recombinant protein corresponding to 154 450 mappingat the carboxy terminus of δ-Tubulin of human origin recombinant protein corresponding to 196 475 mappingat the carboxy terminus of ε-Tubulin of human origin epitope located between 426 450 ; aa 426-430 epitope localizes between 416 430 . alpha tubulin, N-terminal domain (epitope within 65 97 alpha tubulin) synthetic peptide conj. to KLH, corr. to 352 366 human ε-Tubulin purified sea urchin --Lytechinus pictus-- sperm axonemal proteins (epitope localized in the C-terminal region of alpha and beta tubulins, the glutamylated motif at 445 457 alpha tubulin) synthetic peptide conjugated to KLH, corr. to the N-terminal 38 53 γ-Tubulin synthetic peptide conjugated to KLH (epitope: EEFATEGT DRKDVFFY-K, 38 53 ) synthetic peptide conjugated to KLH (epitope: EEFATEGT DRKDVFFY, 38 53 ) synthetic peptide conjugated to KLH (epitope: EEFATEGT DRKDVFFY, 38 53 ) synthetic peptide: DEYHAATRPD YISWGTQEQ-K, with N-terminally added Lysine, conjugated to KLH, corr. to 433 451 γ-Tubulin synthetic peptide: AATRPDYI SWGTQEQ-CG, with N-terminally added cysteine-glycine, conj. to KLH, corr. to 437 451 Xenopus laevis γ-Tubulin crude tubulin preparation ( 65 79 alpha tubulin) sea urchin (Lytechinus pictus) sperm axonemal proteins ( 427 432 in sea urchin β-2 tubulin) purified rat brain tubulin (epitope in the C-terminal part of β-tubulin, between 281 446 ) purified rat brain tubulin (epitope in the C-terminal part of β-tubulin, between 281 446 ) crude tubulin preparation (epitope at 65 79 alpha tubulin) full length S. cerevisiae native protein, purified (epitope between 414 422 ) fraction of tubulin purified from pig brain by two cycles of polymerization- depolymerization (epitope at 65 97 on N-terminal structural domain) synthetic peptide: ESESQGPK conjugated to malemide activated KLH ( 441 448 human tubulin) 1 451 representing full length α tubulin of porcine origin 210 444 β tubulin of human origin 149 448 α tubulin of human origin 269 451 at the C-terminus of γ tubulin of human origin 269 451 at the C-terminus of γ tubulin of human origin purified rat brain tubulin (epitope in the carboxy-terminal part of β-tubulin between 281 446 ) synthetic peptide corr. to the N-terminal region of human γ-tubulin ( 38 53 , with C-terminally added lysine) conjugated to KLH purified rat brain tubulin (epitope in the carboxy-terminal part of β-tubulin between 281 446 ) sea urchin sperm axonemal proteins (epitope in the C-terminal region of β-tubulin, 427 432 in sea urchin β2-tubulin) synthetic peptide corr. to the C-terminus of Drosophila γ-tubulin ( 441 457 with N-terminal added cysteine-glycine) synthetic peptide (corr. to 352 366 ) in the C-terminal region of human ε-tubulin, conjugated to KLH synthetic peptide corr. to the C-terminus of C. elegans γ-tubulin ( 428 444 with N-terminal added cysteine) synthetic peptide corr. to aa 441 450 human β-tubulin III with N-terminal added cysteine, conjugated to KLH synthetic peptide corr. to the C-terminus of human γ-tubulin ( 433 451 , with N-terminally added lysine) conjugated to KLH synthetic peptide corr. to the C-terminus of xenopus γ-tubulin ( 437 451 , with N-terminally added cysteine- glycine) conjugated to KLH synthetic peptide corr. to theN-terminal region of human γ-tubulin ( 38 53 , with C-terminally added lysine) synthetic peptide corr. to theN-terminal region of human γ-tubulin ( 38 53 , with C-terminally added lysine) purified chick brain tubulin (epitope at 426 430 ) synthetic γ-tubulin peptide (N-terminal 38 53 ) conjugated to KLH purified sea urchin sperm axonemal proteins (epitope in C-terminal region of α- and β-tubulins, the glutamylated motif at amino acid 445 457 α-tubulin) (epitope at 65 79 ) ( 2 20 the carboxy terminus of ubiquitin of human origin) 1 46 the amino terminus of ubiquitinof bovine origin epitope corr. to 1 76 full length bovine ubiquitin epitope corr. to 1 76 full length human ubiquitin immnuogen = recombinant protein corr. to 251 410 mapping near C-terminus of human VAChT synthetic peptide corr. to 511 530 from cloned rat VAChT synthetic peptide corr. to 511 530 from cloned rat VAChT synthetic peptide corresponding to 511 530 from cloned rat VAT synthetic peptide corresponding to 511 530 from cloned rat VAT synthetic peptide corresponding to 511 530 from cloned rat VAChT synthetic peptide corresponding to 511 530 from the C-terminal of rat VAChT synthetic peptide corr. to 511 530 from cloned rat VAChT synthetic peptide corresponding to 511 530 from cloned rat VAT synthetic peptide corresponding to 511 530 from cloned rat VAT synthetic peptide corresponding to 511 530 from cloned rat VAChT immnuogen = recombinant protein corr. to 251 410 mapping near C-terminus of human VAChT immnuogen = synthetic peptide corr. to C-terminal of rat VAChT, conj. to KLH ( 512 530 , with N-terminally added lysine) purified, E.Coli-derived recombinant mouse p53, 28 325 1 300 mapping at the N-terminus of PARP-1 of human origin GST-human DJ-1 fusion protein corr. to full length 1 187 GST-human DJ-1 fusion protein corr. to full length 1 187 imunogen = recomb. full-length human DJ-1:GST fusion protein ( 1 187 ) synthetic peptide corresponding to 443 450 (ESESQGPK) of human class III beta-tubulin conj. to KLH. synthetic peptide, corr. to 40 63 human FGF basic synthetic peptide 10 30 amino acids in length) at the N-term of first 50 amino acids of human FGF4 conjugated to KLH recombinant protein to 16 140 hFGF-1 Epitope mapping to 10 130 hFGF-10 recombinant protein corresponding to 1 268 (full length) of hFGF-5 recombinant protein corresponding to 107 200 at C-terminus of hFGF-6 32 104 hFGF-7 53 233 representing all but the N-terminal 52 aa of hFGF-8 25 124
hFGFR-3 25 124 hFGFR-3 25 145 mapping within an extracellular domain of hFGFR-4 1 268 representing full length hFGF-5 53 233 representing all but the N-terminal 52 amino acids of hFGF-8 10 130 human FGF-10 1 208 hFGF-9 25 124 hFGFR-3 25 145 mapping within an extracellular domain of hFGFR-4 25 124 hFGFR-3 22 101 hBek recombinant hFGF-12, 67 243 (purified, E.coli derived) synthetic peptide corresponding to 792 806 the cytoplasmic region of hFGFR-3 with N-terminal added lysine synthetic peptide corresponding to 359 372 extracellular region of hFGFR-3 conjugated to KLH synthetic peptide corr. to internal sequence ( 89 100 ) of human GSK3 alpha synthetic peptide, corresponding to 1 30 human Heme Oxygenase 1 recombinant fragment 1 261 rat HO-1 synthetic peptide 10 33 aa in length) at the N-terminus of the first 100aa of human GSK3α synthetic peptide 10 30 aa in length) at the C-terminus of last 50aa of human GSK3α synthetic peptide 10 30 aa in length) at the C-terminal of last 100aa of human GSK3β synthetic peptide 10 30 aa in length) at the N-terminus of first 50aa of human GSK3β synthetic peptide 10 30 amino acid in length) at the N-terminal of first 50 aa of human GFAP conjugated to KLH synthetic peptide 10 30 aa in length) at the C-terminal of last 50 aa of human GFAP conjugated to KLH synthetic peptide 10 30 aa in length) in the region of 149~164 of hHIP2 synthetic peptide 10 30 aa in length) at the C-terminal of last 50 aa of hHAP1 conjugated to KJH synthetic peptide 10 30 aa in length) at the C-terminal of last 100 aa of hHAPIP conjugated to KLH synthetic peptide corresponding to C-terminal 206 217 human GRB2 1 217 GRB2 synthetic peptide SWDVETATELLLSN, corresponding to C-terminal 187 200 hHIP2 1 217 GRB2 synthetic peptide corresponding to 4 12 human GSK3β synthetic peptide corresponding to 12 25 and Cys-NH₂ of human HO-1 synthetic peptide corresponding to 246 264 amidated form of the human HO-2 protein huntingtin fragment from 181 810 synthetic phospho-peptide corresponding to 302 314 mouse Akt (PKB) synthetic peptide corresponding to 672 713 derived from full-length hβ-amyloid precursor protein synthetic peptide corresponding to 672 713 derived from full-length hβ-amyloid precursor protein synthetic peptide corresponding to 672 713 derived from full-length hβ-amyloid precursor protein synthetic peptide corresponding to 672 713 derived from full-length hβ-amyloid precursor protein synthetic peptide corresponding to 672 713 derived from full-length hβ-amyloid precursor protein synthetic peptide corresponding to 672 713 derived from full-length hβ-amyloid precursor protein synthetic peptide corresponding to 672 713 derived from full-length hβ-amyloid precursor protein synthetic peptide corresponding to 672 713 derived from full-length hβ-amyloid precursor protein synthetic peptide corresponding to 672 713 derived from full-length hβ-amyloid precursor protein synthetic peptide corresponding to 672 713 derived from full-length hβ-amyloid precursor protein synthetic peptide corresponding to 672 713 derived from full-length hβ-amyloid precursor protein synthetic peptide corresponding to 672 683 derived from full length hβ-amyloid precursor protein synthetic peptide conjugated to BSA, corresponding to 461 477 human AKT1 synthetic peptide (coupled to KLH) corresponding to 88 100 human AKT1 α -isoform with an added cysteine residue synthetic peptide corresponding to 302 314 mouse protein kinase B synthetic peptide corresponding to 106 122 human AKT1 synthetic peptide (coupled to KLH) from 400 500 seq of human AKT1 synthetic peptide from within 100 200 human AKT2 conj to KLH synthetic peptide corresponding to the C-terminus ( 460 480 ) of human, rat, mouse and chicken AKT proteins conj to KLH synthetic peptide corresponding to C-terminus 460 480 human, mouse, rat and chicken AKT proteins (conj KLH) synthetic peptide corresponding to 302 311 human AKT conj to KLH synthetic peptide corresponding to 455 468 human AKT2 conj KLH rat AKT 1peptide 465 480 aa) containing a phosphorylated Ser472 conj. KLH mouse Aktα ( 375 479 ) derived from E. coli amino acid 2 200 human AKT 106 122 human AKT1 108 124 human AKT2 synthetic peptide 302 314 mouse AKT rat AKT1 peptide 465 480 containing a phosphorylated Ser472 synthetic peptide corr. to C-terminal 697 703 hAPPL synthetic peptide corresponding to the C-terminus 460 480 human, mouse, rat and chicken AKT proteins conj. to KLH. synthetic peptide corresponding to 302 311 human, AKT protein conj. to KLH. (epitope at 12 25 ) (epitope at 246 264 ) 1 50 human GFAp recombinant protein corresponding to 148 217 mapping at C-terminus of human GRB2 1 68 mapping at the N-terminus of human GRB2 148 217 mapping at the C-terminus of human GRB2 408 483 mapping at the C-terminus of human GSK3α 345 420 mapping at the C-terminus of human GSK3bβ 1 420 representing full length Xenopus GSK3β 1 420 representing full length Xenopus GSK3β 1 420 representing full length Xenopus GSK3β 465 480 peptide of rat AKT1 containing phosphorylated Ser472 conj to KLH 345 480 human AKT1 345 480 human AKT1 345 480 human AKT1 345 480 human AKT1/2 synthetic peptide corresponding to 1 30 human HO-1 recombinant protein corresponding to 239 311 mapping near the C-terminus of human HO-2 epitope corr. to 549 679 peptide corresponding to 314 325 mouse HAP40 372 671 mapping at the C-terminus of human HAP1 cDNA 290 426 rat HAP1 raised against human tau (epitope = first repeat of MBD, 257 274 ) raised against human tau (epitope = second repeat of MBD, 273 283 ) raised against human tau (epitope = C terminal end, 426 441 ) amino acid 71 184 human Akt/PKBα synthetic phospho-peptide corresponding to 464 479 Akt1 phosphorylated at serine 473 synthetic peptide corresponding to 466 479 mouse Akt1 synthetic peptide, C-terminal ( 313 334 ) synthetic peptide, N-terminal ( 21 34 ) synthetic peptides, ( 311 322 ) and (aa 342-353) synthetic peptide, ( 31 45 ) synthetic peptide, C terminal ( 317 334 ) amino acid 150 286 human HO-1 amino acids 5 115 at N-terminal of human HO-2 rat HAP1-A 100 289 human HIP1 228 337 mouse Hip1R 560 772 peptide corresponding to the C-terminus of the large subunit of human ( 163 175 ) and mouse (CRGTELDC-GIETD) caspase-3 recomb. protein corresponding to 1844 2131 huntingtin recomb. protein corresponding to 2703 2911 huntingtin recomb. protein corresponding to 997 1276 huntingtin peptide corresponding to the C-terminus 466 480 Akt coupled to KLH synthetic peptide corresponding to aa residues Cys+ 384 397 human tau isoform 6 (2N4R) protein, conjugated to KLH synthetic peptide corresponding to aa residues Cys+ 384 397 the human tau isoform 6 (2N4R) protein, conjugated to KLH synthetic peptide sequence corresponding to aa 12 25 +Cys-NH₂ of human HO-1 conjugated to KLH synthetic peptide sequence corresponding to aa 245 264 , in amidated form, of human HO-2 conj to KLH synthetic peptide corr. to C-terminus 460 480 human, mouse, rat and chicken AKT proteins conj to KLH. synthetic peptide corr. to C-terminus 302 311 human AKT protein conj to KLH. recomb. protein corresponding to 997 1276 huntingtin recomb. protein corresponding to 2703 2911 huntingtin recomb. protein corresponding to 997 1276 huntingtin synthetic peptide corresponding to 40 63 hFGF basic synthetic peptide corresponding to aa 642 661 human glycogen synthase synthetic peptide corresponding to rat GSK-3β isoform-kinase subdomain XI region ( 335 349 ) peptide corresponding to 134 145 human Akt1 peptide corresponding to 134 145 human Akt1 synthetic peptide corr. to 108 121 human Akt2 synthetic peptide α-isoform, 88 199 , of human Akt1 with an added cysteine coupled to KLH peptide corresponding to 2 23 rat HO-1 conj to KLH synthetic peptide [MANIAVQRIKRE(C)] corresponding to amino acids 1 12 E2-25K/Hip-2 163 175 murine caspase-3 163 175 murine caspase-3 89 100 human GSK-3α 21 36 human GSK-3β synthetic peptide (18 residues)corresp. to 203 219 derived from a region of the catalytic domain of Drosophila GSK-3/shaggy enzyme, coupled to ovalbumin. synthetic peptide corresponding to 203 219 derived from a region of the catalytic domain of the Dropophila GSK/shaggy enzyme coupled to ovalbumin synthetic peptide corresponding to 6 12 human GSK-3β synthetic peptide corresponding to 16 26 human phospho-GSK3α (Ser21) with an N-terminal cysteine added for conjugation. synthetic peptide corresponding to 16 26 human phospho-GSK-3α (Ser21) with an N-terminal cysteine added for conjugation. synthetic peptide corresponding to 335 349 rat GSK-3β conj to KLH GST-fusion protein corresponding to 1 149 human Akt-1 synthetic polypeptide ( 1 20 ) of rat synaptobrevin 2, conj. with KLH polypeptide ( 124 134 ) including phosphorylated Ser129 of human alpha-Synuclein synthetic peptide corresponds to 245 265 from human APH-1a Long/CT synthetic peptide, 441 457 human β-secretase 2 synthetic peptide, 503 518 human β-secretase 2 peptide corr. to N-terminal amino acid 43 62 from rat DBH protein peptide corr. to amino acid 157 172 from human ECT protein peptide corr. to amino acid 780 793 from human furin immunizing peptide corr. to amino acid 103 114 from human Prx 1 immunizing peptide corr. to amino acid 104 115 from human Prx 2 immunizing peptide corr. to 436 441 from human versican protein; sequence is completely conserved between mouse and rat huntingtin fragment from 1247 1646 as a fusion protein recomb. human huntingtin, 115 129 . recomb. human huntingtin, 1 82 444 amino acid peptide containing N-terminal histidine tag corresponding to 1736 2179 mouse CBP (CREB binding protein) synthetic peptide corresponding to 672 683 derived from full length hβ-amyloid precursor protein synthetic peptide corresponding to 672 683 derived from full length hβ-amyloid precursor protein synthetic peptide corresponding to 672 683 derived from full length hβ-amyloid precursor protein synthetic peptide corresponding to 672 683 derived from full length hβ-amyloid precursor protein synthetic peptide corresponding to 672 683 derived from full length hβ-amyloid precursor protein synthetic peptide corresponding to 672 683 derived from full length hβ-amyloid precursor protein synthetic peptide corresponding to 672 683 derived from full length hβ-amyloid precursor protein synthetic peptide corresponding to 672 683 derived from full length hβ-amyloid precursor protein synthetic peptide corresponding to 162 176 in the nuclear factor binding domain of human CBP synthetic peptide corresponding to 162 176 in the nuclear factor binding domain of hCBP. synthetic peptide corresponding to 162 176 in the nuclear factor binding domain of hCBP synthetic peptide corresponding to a portion of human CREB binding protein (CBP) encoded within exon 33. Sequence conserved in 28 31 residues between human and mouse. synthetic peptide corresponding to 162 176 in the nuclear factor binding domain of human CBP recombinant protein corresponding to 671 970 mapping within an internal region of human CBP recombinant protein corresponding to 671 970 mapping within an internal region of human CBP fusion protein containing 720 1676 mouse CBP synthetic peptide corresponding to 162 176 in the nuclear factor binding domain of human CBP 444 amino acid peptide containing N-terminal histidine tag corresponding to 1736 2179 mouse CBP (epitope between 56 78 ) of the human DJ-1 protein (epitope between 26 56 ) of the human DJ-1 protein purified recominant human GRB-2 protein (epitope between 54 62 ) synthetic peptide corresponding to aa 89 106 from human aggrecan protein synthetic peptide corresponding to 119 136 human Akt3. 465 480 peptide of rat AKT1 containing phosphorylated Ser472 conj to KLH synthetic peptide corresponding to 4 12 human GSK3β synthetic peptide corresponding to the C-terminus 460 480 human, mouse, rat, chicken AKT proteins coupled to KLH synthetic peptide corresponding to the C-terminus 460 480 human, mouse, rat, chicken AKT proteins coupled to KLH synthetic peptide corresponding to 302 311 human AKT protein coupled to KLH synthetic peptide corresponding to C-terminus 460 480 human, rat, mouse, chicken AKT proteins coupled to KLH synthetic peptide corresponding to 455 468 human AKT2 protein coupled to KLH (epitope within 1844 2131 ) (epitope within 2703 2911 ) (epitope within 1171 1177 ) 314 325 synthetic peptide corresponding to 460 480 human Akt conj to KLH synthetic peptide corresponding to 302 311 Akt synthetic peptide corresponding to 302 314 mouse PKB C-terminus 460 480 human, rat and chicken Akt proteins conj to KLH recombinant fragment corresponding to 2 200 human Akt synthetic peptide corresponding to 88 100 human Akt α isoform with a C-terminal cysteine added and coupled to KLH synthetic peptide corresponding to 461 477 human Akt1 synthetic peptide corresponding to 108 124 human Akt2 synthetic peptide corresponding to 119 136 human Akt3 synthetic peptide corresponding to 119 136 human Akt3 synthetic peptide RRTT_pSFAE, corresponding to 4 12 Human GSK3 beta synthetic peptide corresponding to 3 13 porcine GFAP 1 217 GRB2 synthetic peptide corresponding to C-terminal 206 217 human GRB2 synthetic peptide corr. to 1 30 rat Heme Oxygenase-1 synthetic peptide corresponding to 1 30 human HO-1 recombinant fragment 1 261 rat HO-1 recombinant fragment corresponding to 18 218 (N-terminal) of human syndecan recombinant fragment corresponding to 18 218 (N-terminal) of human syndecan recombinant fragment corresponding to 18 218 (N-terminal) of human syndecan recombinant fragment corresponding to 18 218 (N-terminal) of human syndecan recombinant protein corresponding to 997 1276 huntingtin recombinant protein corresponding to 1844 2131 huntingtin recombinant protein corresponding to 2703 2911 huntingtin 1171 1177 (HDA region of huntingtin 1844 2131 corresponding to HDB region of huntingtin recombinant protein corresponding to 2703 2911 huntingtin recombinant carboxyl terminal half of the full length human protein (65-kDa); epitope is 750 780 synthetic peptide corresponding to aa 95 112 human HIPPI synthetic peptide derived from 50 150 human HIPPI 314 325 [DGHGQD TSGQLP] of the 40 kDa mouse HAP40 protein peptide corr. to 314 325 the 40 kD mouse HAP40 protein synthetic peptide corresponding to 162 176 in the nuclear factor binding domain of human CBP synthetic peptide corresponding to 464 477 human Akt1 synthetic peptide corresponding to 119 136 human Akt3 synthetic peptide corresponding to 119 136 human Akt3 synthetic phospho peptide corresponding to 302 311 Human AKT protein conjugated to KLH synthetic phospho peptide corresponding to 416 424 Human huntingtin protein synthetic peptide 335 349 rat GSK3β synthetic peptide corresponding to aa 12 25 human HO-1 protein recombinant protein corresponding to 997 1276 huntingtin recombinant protein corresponding to 1844 2131 huntingtin recombinant protein corresponding to 2703 2911 huntingtin recomb. protein corresponding to 1 50 mapping at the amino terminus of human GFAP amino acid 181 810 as a fusion protein amino acid region 1 14 (VETSDHDNSLSVSI) conj to KLH synthetic peptide corresponding to C-terminal 468 477 human AKT synthetic peptide corresponding to 302 311 Akt 40 kDa mouse HAP40 protein ( 314 325 ) Synthetic peptide: RRRVT-phospho SAARRS conjugated to KLH, corr. to 3 13 Pig GFAP peptide corresponding to 460 480 at C-terminus of human, rat, mouse and chicken Akt proteins, conjugated KLH recombinant fragment corresponding to 2 200 human Akt synthetic peptide corresponding to 88 100 human Akt α isoform with a C-terminal cysteine added coupled to KLH synthetic peptide corresponding to 455 468 human Akt2 synthetic peptide corresponding to 108 124 human Akt2 synthetic peptide corresponding to 119 136 human Akt3 synthetic peptide corresponding to 119 136 human Akt3 synthetic peptide corresponding to 302 314 mouse protein kinase B synthetic peptide corresponding to 455 468 human Akt2 synthetic peptide corresponding to 116 128 rat Akt3 peptide corresponding to 460 480 at C-terminus of human, rat, mouse and chicken Akt proteins, conjugated KLH recombinant fragment corresponding to 2 200 human Akt synthetic peptide corresponding to 88 100 human Akt α isoform with a C-terminal cysteine added and coupled to KLH synthetic peptide corresponding to C-terminal 468 477 human AKT synthetic peptide corresponding to 302 311 Akt synthetic peptide corresponding to 106 122 human AKT1 synthetic peptide (coupled to KLH) corresponding to 88 100 human AKT1 α -isoform with an added cysteine residue synthetic peptide conjugated to BSA, corresponding to 461 477 human AKT1 synthetic peptide corresponding to 108 124 human Akt2 synthetic peptide corresponding to 119 136 human Akt3 synthetic peptide corresponding to 119 136 human Akt3 synthetic peptide RARTS_pSFAEPC, corresponding to 16 25 Human GSK3 alpha synthetic peptide RARTSSFAEPC, corresponding to 16 25 Human GSK3 alpha synthetic peptide RRTT_pSFAE, corresponding to 4 12 Human GSK3 beta synthetic peptide corr. to internal sequence ( 89 100 ) of human GSK3 alpha synthetic peptide corresponding to 14 27 human HO2 synthetic peptide corresponding to 14 27 human HO2 synthetic peptide, corresponding to 1 30 human Heme Oxygenase 1 recombinant fragment 1 261 rat HO-1 synthetic peptide corr. to 1 30 rat Heme Oxygenase-1 recombinant fragment corresponding to 18 218 (N-terminal) of human syndecan recombinant fragment corresponding to 18 218 (N-terminal) of human syndecan recombinant protein corresponding to 997 1276 huntingtin synthetic peptide corresponding to 162 176 in the nuclear factor binding domain of human CBP synthetic peptide derived from 50 150 human HIPPI Epitope = 54 62 amino acid 2 200 Akt1 amino acid 106 122 Akt1 amino acid 108 124 Akt2 124 144 Akt3 GSK-3α peptide ( 89 100 ) GSK-3β peptide ( 21 36 ) synthetic peptide corresponding to 162 176 in the nuclear factor binding domain of human CBP (epitope corr. to 103 114 human Prx-1) (epitope corr. to 104 115 human Prx-2) peptide corresponding to 335 349 rat GSK-3β synthetic peptide corresponding to 88 100 human PKB α isoform with a c-terminal cysteine added and coupled to KLH recombinant human GFAP 292 432 derived from e. coli synthetic peptide corresponding to 75 90 human Akt1 and Akt2, and aa 74-89 Akt3 E. coli derived recombinant human v-akt murine thymoma viral oncogene homolog 1 ( 2 480 ) recombinant human Aggrecan ( 20 675 ) NSO-derived recombinant human Aggrecan ( 20 675 ) NSO-derived recombinant mouse Syndecan-3 ( 45 384 ) NSO-derived synthetic peptide corresponding to internal sequence 120 133 human Akt3 synthetic peptide corresponding to the C-terminus 460 480 human, rat, mouse and chicken Akt synthetic peptide corresponding to the C-terminus 460 480 human, mouse, rat, chicken akt synthetic peptide (DGATMKpTFCG) corresponding to 302 311 human Akt coupled to KLH synthetic peptide corresponding to 455 468 human Akt2 conj to KLH synthetic peptide corresponding to 16 25 human GSK3α synthetic peptide (RARTSSFAEPC)corresponding to 16 25 human GSK3α synthetic peptide (RPRTTsFAE) corresponding to 4 12 human GSK3β synthetic peptide corresponding 416 424 human huntingtin 148 217 human GRB2 54 164 mapping to central domain of mouse GRB2 mapping between 1 68 mouse GRB2 148 217 mapping at the C-terminus of human GRB2 1 68 mapping at the N-terminus of human GRB2 1 420 representing full length Xenopus GSK-3β 408 483 at the C-terminus of human GSK-3α 345 480 human Akt1 345 480 human Akt1/2 239 311 human Heme Oxygenase-2 1911 1962 human aggrecan 4092 4391 mapping at the C-terminus of human Perlecan 1 140 mapping near the N-terminus of human Syndecan-4 1 140 mapping near the N-terminus of mouse Syndecan-2 1 300 mapping near the N-terminus of mouse Syndecan-3 82 256 human Syndecan 372 671 mapping at the C-terminus of human HAP1 329 628 at the C-terminus of mouse HAP1B cDNA 290 426 rat HAP-1 amino acid 671 970 human CBP recombinant protein corresponding to 997 1276 Huntingtin recombinant protein corresponding to 1844 2131 Huntingtin recombinant protein corresponding to 2703 2911 huntingtin synthetic peptide corresponding to the C-terminal region of human GSK-3β ( 403 420 ) conj to KLH synthetic peptide corresponding to the C-terminal region of human, rat and mouse Grb2 ( 200 217 ) conjugated to KLH synthetic peptide corresponding to the C-terminus of mouse glutamine synthetase ( 357 373 ) coupled to KLH synthetic peptide corresponding to 464 477 human Akt1 synthetic peptide (ASIRE) based on human PKBβ/AKT2 ( 477 481 ) coupled to KLH synthetic peptide based on the human PKB, α isoform ( 88 100 ) with a cysteine residue added and coupled to KLH phos-phorylated peptide corresponding to 3 13 porcine GFAP coupled to KLH synthetic peptide corresponding to 195 217 human Grb2 coupled to KLH synthetic peptide corresponding to 195 217 human Grb2 coupled to KLH synthetic peptide corresponding to 195 217 human Grb2 coupled to KLH synthetic peptide corresponding to 195 217 human Grb2 coupled to KLH mapping between 1 68 mouse GRB2 54 164 mapping to central domain of mouse GRB2 148 217 mapping at the C-terminus of human GRB2 1 68 mapping at the N-terminus of human GRB2 148 217 human GRB2 mapping between 1 68 mouse GRB2 phos-phorylated peptide corresponding to 3 13 porcine GFAP coupled to KLH recomb. protein corresponding to 1 50 mapping at the amino terminus of human GFAP synthetic peptide corresponding to 16 25 human GSK3α synthetic peptide corresponding to 16 25 human GSK3α synthetic peptide (RPRTTsFAE) corresponding to 4 12 human GSK3β immunogen = synthetic peptide based on the rat GSK-3β isoform-kinase subdomain XI region ( 335 349 ) 408 483 at the C-terminus of human GSK-3α 1 420 representing full length Xenopus GSK-3β 345 420 mapping at the C-terminus of human GSK-3β 345 420 mapping at the C-terminus of human GSK-3β synthetic peptide corresponding to the C-terminus 460 480 human, rat, mouse and chicken Akt synthetic peptide corresponding to the C-terminus 460 480 human, mouse, rat, chicken akt synthetic peptide (DGATMKpTFCG) corresponding to 302 311 human Akt coupled to KLH synthetic peptide corresponding to 455 468 human Akt2 conj to KLH amino acid 671 970 human CBP peptide corresponding to the C-terminus 466 480 Akt coupled to KLH 345 480 human Akt1 345 480 human Akt1/2 synthetic peptide based on the human PKB, α isoform ( 88 100 ) with a cysteine residue added and coupled to KLH synthetic peptied (ASIRE) based on the human PKBβ ( 477 481 ) coupled to KLH 1911 1962 human aggrecan 4092 4391 mapping at the C-terminus of human Perlecan 82 256 human Syndecan 1 140 mapping near the N-terminus of mouse Syndecan-2 1 300 mapping near the N-terminus of mouse Syndecan-3 1 140 mapping near the N-terminus of human Syndecan-4 epitope corr. to 2845 3144 mapping at the C-terminus of human Huntingtin Huntingtin fusion recomb. protein 549 679 amino acid 671 970 human CBP amino acid 671 970 human CBP cDNA 290 426 rat HAP-1 372 671 mapping at the C-terminus of human HAP1 329 628 at the C-terminus of mouse HAP1B 365 480 human HIP1 glial fibrillary acidic protein 51 52 kD) Glial Fibrillary Acidic Protein 51 52 kD) synthetic peptide corresponding to 1 217 human Grb2 1 217 human Grb2 fusion protein corresponding to 1 149 human Akt1 synthetic peptide corresponding to C-terminus 460 480 human, rat, mouse and chicken Akt a 13 residue synthetic peptide FHVETPEEREEWT(C) based on human PKB kinase, α isoform ( 88 100 ) plus cysteine coupled to KLH E. coli expressed mouse Akt ( 375 479 ) 2 200 Akt recombinant protein corresponding to 140 480 human Akt1 synthetic peptide corresponding to 464 477 human Akt1 fusion protein corresponding to 1 149 human Akt1 15 residue synthetic peptide (C-RPHFPQFSYSASGTA) corresponding to the C-terminal ( 466 480 ) of rat Akt1. synthetic peptide corresponding to 2 200 Akt1 synthetic peptide corresponding to 106 122 human Akt1 106 122 human Akt1 synthetic peptide (FHVETPEEREEWT-C) corresponding to 88 100 human Akt1/PKBα plus cysteine coupled to KLH synthetic peptide corresponding to the C-terminal 466 480 ) of rat Akt1/PKBα, plus N-terminal cysteine coupled to KLH synthetic peptide C-RYDSLGSLELDQRTH corresponding to 455 469 human Akt2, coupled to KLH synthetic peptide (CRYDSLGSLELD QRTH) corresp. to 455 469 human Akt2/PKB, plus N-terminal cysteine, coupled KLH synthetic peptide (CRYDSLGSLELDQRTH) corresp. to 455 469 human Akt2/PKBβ, plus an N-terminal cysteine, coupled to KLH. synthetic peptide corresponding to 455 468 human AKT 2. Amino acid sequence: RYDSLG LLELDQRT. 108 124 human Akt2 synthetic peptide corresponding to 108 124 human Akt2 synthetic peptide corresponding to aa 119 136 human Akt3 synthetic peptide corresponding to aa 116 128 rat Akt3. 124 144 human Akt3 synthetic peptide corresponding to 119 131 (CSPTSQID NIGEE) of human Akt3/PKBγ synthetic peptide corresponding to aa 119 136 human Akt3 synthetic peptide corresponding to 124 144 human Akt3 recombinant protein corresponding to 140 480 human Akt1 recombinant protein containing 140 480 human Akt1 synthetic peptide corresponding to 203 219 derived from a region of the catalytic domain (between subdomain VII and VIII) of the Drosophila GSK-3/ shaggy enzyme (ovalbumin coupled). Synthetic peptide corresponding to 471 483 rat GSK3α, coupled to KLH synthetic peptide corresponding to 89 100 human GSK3α peptide corresponding to 89 100 human GSK-3α 21 36 human GSK-3β peptide synthetic peptide corresponding to 16 26 the human GSK-3α coupled to KLH synthetic peptide corresponding to 471 483 rat GSK3α coupled to KLH Immunogen - synthetic peptide corresponding to 471 483 rat GSK3α synthetic peptide corresponding to 16 26 human phospho-GSK3α (Ser21), coupled to KLH synthetic peptide corresponding to 16 26 human phospho-GSK3α (Ser21), coupled to KLH synthetic phospho-peptide corresponding to 6 12 with phosphorylated Ser9 of human GSK3β synthetic peptide corresponding to 203 219 derived from a region of the catalytic domain of the Drosophila GSK/shaggy enzyme coupled to ovalbumin synthetic peptide corresponding to 203 219 derived from the region of the catalytic domain of Drosophila GSK/shaggy enzyme, coupled to KLH synthetic peptide corresponding to 471 483 rat GSK-3α, coupled to KLH GST-fusion protein corresponding to aa 1 149 human Akt1 GST-fusion protein corresponding to aa 1 149 human Akt1 GST-fusion protein corresponding to aa 1 149 human Akt1 synthetic peptide corresponding to the C-terminal 466 480 rat Akt1 synthetic peptide corresponding to 455 469 human Akt2/PKBβ synthetic peptide corresponding to 119 131 human Akt3/PKBγ synthetic peptide corresponding to the C-terminal 466 480 rat Akt1 synthetic peptide corresponding to 88 199 human Akt1/PKBα Pleckstrin Homology Domain coupled to KLH synthetic peptide corresponding to 455 469 human Akt2/PKBβ coupled to KLH synthetic peptide corresponding to 119 131 human Akt3/PKBγ Immuogen = synthetic peptide corresponding to 301 312 with phospho-Thr at aa 308 of mouse Akt coupled to KLH synthetic peptide corresponding to 6 12 (RTT[pS]FAE) of human GSK3β coupled to KLH Synthetic peptide corresponding to 203 219 the catalytic domain (between subdomain VII & VIII) of Drosophila GSK-3/shaggy enzyme coupled to ovalbumin. synthetic peptide corresponding to 335 349 rat GSK-3β isoform-kinase subdomain XI region synthetic peptide corresponding to 21 36 human GSK-3β recombinant rat HO-1 purified from E. coli containing 1 261 from HO-1, 7aa from N-terminus and 12 aa from C-terminus of expression vector synthetic peptide based on the human HO-1 ( 1 30 ) synthetic peptide corresponding to 1 30 human heme-oxygenase 1 (HO-1). Prepared as a four branched multiple antigen peptide. human aggrecan 1 14 : V-E-T-S-D-H-D-N-S-L-S-V-S-I). human aggrecan 1 14 : V-E-T-S-D-H-D-N-S-L-S-V-S-I) coupled to KLH recombinant protein corresponding to 1844 2131 huntingtin recombinant protein corresponding to 2703 2911 huntingtin recombinant protein corresponding to 997 1276 huntingtin E1A affinity purified p300 protein. Epitope: 2071 2091 E1A affinity purified p300 protein. Epitope: 2071 2091 GST fusion protein corresponding to 1 233 bovine MsrA. Human homology 219/233 synthetic peptide corresponding to 104 115 human Prx1 synthetic peptide corresponding to 103 114 human Prx2 GST fusion protein corresponding to 1 233 bovine MsrA synthetic peptide corresponding 416 424 human huntingtin synthetic peptide corresponding to 104 115 human PrxI synthetic peptide corresponding to 103 114 human PrxII synthetic phospho-peptide corresponding to 302 314 mouse Akt (PKB) synthetic peptide corresponding to 119 136 human Akt3. Synthetic peptide: C-A-A-Q-V-K-A-P-L-V-L-K-D, corresponding to C terminal 178 189 human PARK7/DJ1 synthetic peptide, corresponding to 6 23 human CREB synthetic peptide K R R E I L S R R P S Y R K corresp. to 123 136 human CREB. synthetic phospho-peptide K(123) R R E I L S R R P (pS) Y R K (136) corresp. to aa 123 136 from human CREB synthetic peptide corresponding to a region near the N-terminus ( 5 45 ) of human CREB synthetic peptide: C T R F T D E Y Q L F E E L corresp. to N terminal 7 20 rat CaMKII (delta isoform ) N-terminal fusion protein corresponding to 25 130 rat NMDA receptor 2C. C-terminal fusion protein, corresponding to 1253 1391 rat NMDA receptor 2B 1437 1456 mature mouse NR2B or 1463-1482 of NR2B precursor; signal is amino acid residues 1-26 [K F N G S S N G H V Y E K L S S I E S D V] fusion protein, corresponding to 780 914 from the intracellular IIIIV loop of Human NR3A + NR3B. fusion protein, corresponding to 1 564 NMDAR1 synthetic peptide containing amino acid 96 113 human κB-Ras1 130 143 human IkBα protein synthetic peptide corresponding to 34 48 human IkBα protein recombinant protein corresponding to amino acid 32 391 human IkBα recombinant protein corresponding to amino acid 32 391 human IkBα was used as immunogen synthetic peptide within aa 500 600 human TBK-1 synthetic peptide corresponding to 526 539 human NF-kB (p65) synthetic peptide corresponding to 538 546 human NFκB p65 273 284 (R-R-P-p-D-R-E-L-p-E-P-M) of human NF-kB p65 (p=Ser) A synthtic peptide conatining amino acid 10 28 (IEIIEQPRQRGMRFRYKCE) of human c-Rel. A synthetic peptide corresponding to amino acid 276 291 (DFRYLPDEKDTYGNKA) of human c-Rel peptide V L L S R K R R R Q H G Q C corresp. to 1755 1767 the N-terminal sequence of the cleaved N intracellular domain (NICD). synthetic peptide C R D A S N H K R R E P V G Q D corresp. to 1719 1733 human activated Notch2 peptide C N A A E R T P S H S G H L Q corresp. to 2396 2409 Notch 2 peptide C E H P F L T P S P E S P D Q corresp. to 2507 2520 at the C-terminus of Notch 1 synthetic peptide: C Q H S Y S S P V D N T P S H Q corresp. to 2488 2502 Notch1 intra synthetic peptide (A W H A P G D D L R P E A L C) corresp. to 121 134 human Delta4, coupled to KLH synthetic peptide K A S R G N D R N R I V L P F S C corresponding to 110 125 Human Jagged1 coupled to KLH synthetic peptide: A G D R A R A R S R T G G H Q D P G corresp. to 111 128 mouse Jagged 2. synthetic peptide selected within 400 478 human CAMK2α synthetic peptide selected within 500 550 human CAMK2β. synthetic peptide selected from 324 338 human CAMK2 δ-like synthetic peptide selected within 450 499 human CAMK2δ synthetic peptide selected from 397 411 human CAMK2γ. Immnogen = synthetic peptide 10 30 aa in length) at the C-term of last 50 aa of human Notch1. Immunogen synthetic peptide 10 30 aa in length) at the C-term of last 50 aa of human Notch2. synthetic peptide 10 30 aa in length) at the C-term of last 50 aa of human Notch3 synthetic peptide 10 30 aa in length) at the C-term of last 50 aa of human Notch4 synthetic peptide 10 30 aa in length) at the C-term of last 50 aa of human Jag1 synthetic peptide: C G E E W S Q D L H S S G R T D L R Y S corresponding to 155 173 mouse Delta-1 coupled to KLH peptide corresponding to a region near the N-terminus ( 5 45 ) of human CREB coupled to KLH phospho peptide Q K R R E I L S R R P (pS) Y R K I L N D L S S D A P corresp. to 122 147 human CREB thyroglobulin-coupled peptide corresponding to 17 35 NR1 peptide V L L S R K R R R Q H G Q C corresp. to 1755 1767 the N-terminal sequence of the cleaved N intracellular domain (NICD). synthetic peptide corresponding to aa 2488 2502 (C Q H S S Y S S P V D N T P S H Q) of human notch 1 peptide C N A A E R T P S H S G H L Q corresp. to 2396 2409 Notch 2 synthetic peptide corresponding to 6 23 human CREB-1 synthetic peptide corresponding to 6 23 human CREB-1 synthetic peptide corresponding to 167 189 (A-I-V-E-A-L-N-G-K-E-V-A- A-Q-V-K-A-P-L-V-L-K- D) of DJ-1/PARK phospho-peptide corresponds to amino acid 123 136 from human CREB synthetic peptide corresponding to aa 123 136 (K R R E I L S R R P S Y R K) of CREB recombinant protein: NR2B subunit amino acid 934 1457 fusion protein corresponding to 1 564 rat NMDA NR1 synthetic peptide corresponding to 125 135 CREB phosphorylated at Ser133 synthetic thiophos-phated (Thr286) peptide corresp. to 281 294 from the α-subunit of mouse and rat CaM kinase II peptide corr. to a region near the N-terminus ( 5 45 ) of the human protein conj. to KLH synthetic peptide corresponding to 100 150 human CREB synthetic peptide corresponding to aa 2507 2520 (C E H P F L T P S P E S P D Q) of human Notch 1 synthetic peptide selected from 397 411 human CAMK2γ. imunogen = recomb. full-length human DJ-1:GST fusion protein ( 1 187 ) Immnogen = synthetic peptide 10 30 aa in length) at the C-term of last 50 aa of human Notch1. Immunogen synthetic peptide 10 30 aa in length) at the C-term of last 50 aa of human Notch2. synthetic peptide 10 30 aa in length) at the C-term of last 50 aa of human Notch3 synthetic peptide 10 30 aa in length) at the C-term of last 50 aa of human Notch4 synthetic peptide 10 30 aa in length) at the C-term of last 50 aa of human Jag1 synthetic peptide 10 30 aa in length) of last 50 aa at the C-term of human Jag2 synthetic peptide 10 30 aa in length) of last 50 aa at the C-term of human Jag2 peptide V L L S R K R R R Q H G Q C corr. to 1755 1767 the N-terminal sequence of the cleaved N intracellular domain (NICD). synthetic peptide: C Q H S Y S S P V D N T P S H Q corresp. to 2488 2502 Notch1 intra synthetic peptide C R D A S N H K R R E P V G Q D corresp. to 1719 1733 human Notch2 peptide V L L S R K R R R Q H G Q C corr. to 1755 1767 the N-terminal sequence of the cleaved N intracellular domain (NICD). synthetic peptide: C Q H S Y S S P V D N T P S H Q corresp. to 2488 2502 Notch1 intra synthetic peptide C R D A S N H K R R E P V G Q D corresp. to 1719 1733 human Notch2 phospho peptide Q K R R E I L S R R P(pS) Y R K I L N D L S S D A P corresp. to 122 147 human CREB, conj. to KLH peptide corresponding to a region near the N-terminus ( 5 45 ) of human CREB coupled to KLH phospho peptide Q K R R E I L S R R P (pS) Y R K I L N D L S S D A P corresp. to 122 147 human CREB, conj. to KLH peptide corresponding to a region near the N-terminus ( 5 45 ) of human CREB coupled to KLH C-terminal fusion protein, corr. to 1253 1391 rat NMDA receptor 2A C-terminal fusion protein, corr. to 984 1104 NMDA receptor 2B C-terminal fusion protein, corr. to 1253 1391 rat NMDA receptor 2A C-terminal fusion protein, corr. to 984 1104 NMDA receptor 2B 268 386 human NMCAε4 27 76 mapping within an extracellular domain of human NMDAε 2 19 318 mapping within an extracellular domain of human NMDAζ 1 268 386 mapping to an internal region of human glutamate NMDAε 4 254 327 mapping within the DNA binding and dimerization domain of human CRED-1 p43 254 327 mapping within the DNA binding and dimerization domain of human CRED-1 p43 1 290 human CREB-2 1 290 human CREB-2 1 290 human CREB-2 254 327 human CREB 254 327 human CREB 254 327 mapping within the DNA binding and dimerization domain of human CREB-1 p43 254 327 mapping within the DNA binding and dimerization domain of human CREB-1 p43 25 255 mapping within an extracellular domain of human Notch 2 2107 2240 mouse Notch 3 1779 2003 mapping at the C-terminus of mouse Notch 4 amino acid 1299 1492 (region EGF repeat 33 through LNG repeat 1) of mouse Notch 1 20 150 mapping within an extracellular domain of human Notch 1 207 272 human Jagged 1110 1223 human Jagged 914 1056 human Jagged 2 459 723 human delta synthetic peptide corresponding to 877 889 (S H S S G M P L G A T G L) at the C-terminus of rat GluR1 synthetic peptide corresponding to 868 881 (R Q S S G L A V I A S D L P) of the C-terminus of rat GLUR4 recombinant trpE fusion protein containing the putative N-terminal 175 430 GluR2 fusion protein encoding GTS in frame with rat NMDAR1 660 811 C-terminal fusion protein corresp. to 25 130 NMDAR2B C-terminal fusion protein corresp. to 984 1104 NMDAR2B mouse NMDAR2A 1093 1214 at C-terminus 892 1051 near C-terminus of rat NMDAR2B C-terminal fusion protein corresp. to 1253 1391 NMDAR2A CREB-1 (p43) peptide corresp. to a region near the N-terminus ( 5 45 ) of the human protein conjugated to KLH C-terminal fusion protein of NMDAR2B aa 984 1104 C-terminal fusion protein of rat NMDAR2A, 1253 1391 synthetic peptide corresponding to 125 135 (R E I L S R R P pS Y R) of human CREB phosphorylated at Ser 133 synthetic peptide corresponding to 123 136 human CREB synthetic phospho-peptide corresponding to 123 136 human CREB phosphorylated (Thr286) peptide corresponding to 281 294 (M H R Q E T V D C L K K F N) of the mouse/rat CaM kinase II α subunit fusion protein containing 1253 1391 NMDAR 2A-subunit fusion protein containing 984 1104 NMDAR 2B subunit a 17 kDa fusion protein constructed from the N-terminal region 25 130 the rat NMDAR 2C subunit synthetic phospho-peptide corresp. to 891 902 rat NMDA receptor subunit NR1 synthetic phospho-peptide corresponding to 891 902 rat NMDA receptor subunit NR1 fusion protein containing 1 564 rat NMDA NR1 synthetic peptide corresponding to 271 285 rat GluR1 synthetic phospho-peptide corresp. to 826 836 mature GluR1 from mouse and rat synthetic peptide corresp. to 840 850 the mature chain, with a phosphorylated serine at position 845. GST-fusion protein containing 1299 1492 mouse Notch 1 GST-fusion protein corresponding to aa 2272 2488 rat Notch 1 GST-fusion protein corresponding to aa 381 853 rat Notch 1 synthetic peptide corresponding to 162 176 in the nuclear factor binding domain of human CBP synthetic peptide corresponding to aa 123 136 (K R R E I L S R R P S Y R K) of CREB phospho-peptide corresponds to amino acid 123 136 from human CREB synthetic peptide corresponding to aa 123-(pS 133 136 human CREB synthetic peptide corresponding to aa 123-(pS 133 136 human CREB fusion protein of NR3A aa 780 914 from the extracellular III-IV loop fusion protein of NR3A 780 914 from the extracellular III-IV loop. fusion protein containing aa 25 130 N-terminal of rat brain subunit 2C fusion protein containing aa 984 1104 C-terminal of rat brain subunit 2B fusion protein containing aa 1253 1391 C-terminal of rat brain subunit 2A fusion protein containing 1253 1391 the C-terminal region of rat brain subunit 2A fusion protein containing 984 1104 the C-terminal region of rat brain subunit 2B fusion protein containing 25 130 the N-terminal region of rat brain 2C subunit fusion protein containing 1 564 the NR1-subunit of rat NMDAR CREB-1 (p43) peptide corresponding to the N-terminal 5 45 human protein conjugated to KLH synthetic peptide corresponding to 125 135 human CREB conjugated to KLH synthetic phospho-peptide corresponding to 123 136 rat CREB coupled to KLH synthetic peptide (REILSRRP[pS]YR) corresp. to 125 135 human CREB synthetic phospho-peptide corresp. to 123 136 (KRREILSRRP[pS]YRK) of rat CREB coupled to KLH synthetic peptide (CSGENQQSGDA AVTEAENQQ) corresp. to 5 24 human CREB synthetic peptide (CSGAENQQSGD AAVTEAENQQ) corresp. to 5 24 human CREB. C-terminal fusion protein of 1253 1391 rat NMDAR 2A C-terminal fusion protein of 1253 1391 rat NMDAR 2A C-terminal fusion protein of 984 1104 from NMDAR 2B fusion protein of 1 564 rat NR1 a GST fusion protein of amino acid region 1099 1213 from human NMDAR 2A GST fusion protein of aa region 1033 1161 from human NMDAR 2B synthetic peptide from 2396 2409 human Notch 2 GST fusion protein comprising 1299 1492 mouse Notch 1 GST-fusion protein corresponding to 1299 1492 mouse Notch 1 His-tag fusion protein containing the C-terminus nucleotides 5708 6217 murine Notch 4 His-tag fusion protein containing the C-terminus nucleotides 5935 6454 murine Notch 3 GST-fusion protein corresponding to 2272 2488 rat Notch 1 N-terminal GST fusion protein corresponding to 381 853 rat Notch 1 GST fusion protein corresponding to 2272 2488 rat Notch 1 N-terminal GST fusion protein corresponding to 381 853 rat Notch 1 His-tag fusion protein containing the C-terminus 5935 6454 murine Notch 3 His-tag fusion protein containing the C-terminus 5708 6217 murine Notch 4 fusion protein from 1 564 rat NMDA NR1 Drosophila Notch extracellular domain, EGF repeat 5 7 Drosophila Notch protein, extracellular domain, EGF repeats # 12 20 , bacterial fusion protein GST fusion protein Notch intracellular domain nucleotides 6658 7131 synthetic peptide (CSGAENQQSGD AAVTEAENQQ) corresp. to 5 24 human CREB coupled to KLH synthetic phospho-peptide corresp. to 123 136 [KRREILSRRP(pS)Y-RK] of rat CREB coupled to KLH. amino acid 1299 1492 (region EGF repeat 33 through LNG repeat 1) of mouse Notch 1 amino acid 1299 1492 (region EGF repeat 33 through LNG repeat 1) of mouse Notch 1 synthetic peptide (REILSRRP[pS]YR) corresp. to 125 135 human CREB coupled to KLH synthetic peptide (Q-K-R-R-E-I-L-S--R-R-P-[pS]-R-K-I-L-N-D-L-S-S-D-A-P) 122 147 corresp. to the human CREB pS133 coupled to KLH). synthetic peptide corresponding to 281 294 rat CaM Kinase II α-subunit synthetic peptide (KMHRQE[pT]VDCLK) correspond. to 281 291 rat CaM Kinase II α-subunit synthetic peptide C-T-R-F-T-D-E-Y-Q-L-F-E-E-L based on the rat multi-functional CaM kinase II δ isoform ( 7 20 ) coupled to KLH rat CaMK II synthetic peptide ( 7 20 )1, conjugated to KLH synthetic peptide corresp. to 499 513 human CAMK2b synthetic peptide 281 291 (K-M-H-R-Q-E-[pT]V-D-CL-K) corresp. to rat CaMkinase II, subunit GST fusion protein corresponding to 934 1457 rat NR2B. 6His-tagged fusion protein corresp. to 1265 1464 mouse NMDA receptor 2A (NR2A) His tag fusion protein corresp. to 834 938 rat NR1A; the epitope maps to a region (834-864) common to all NR1 isoforms peptide corresponding to 916 930 (C R R V R R A V V E R E R R V R) of mouse NR3B peptide corresp.to 259 278 (K R Y A P D G I I G L Q L I N G K N E S) of rat NMDA receptor 1, splice variants 1-4 and aa281-300 on all other splice variants peptide corresp. to 1098 1113 (S R K T E L E E Y Q K T N R T C) of rat NR3A 6His-tagged fusion protein corresp.to 1265 1464 mouse NMDA receptor 2A (NR2A). peptide corresp. to 1297 1309 human phospho-NR2B synthetic peptide (K F K R R R S pS K D T S T) corresp. to 891 902 rat NR1A, thyroglobulin conjugated synthetic peptide (K F K R R R pS S K D T S T) corresp. to 891 902 rat NR1A coupled to thyroglobulin peptide (C R D H T R V D W K R P K) corresp. to 276 287 rat glutamate receptor 1 (GluR1), plus cysteine for conjugation purposes. synthetic peptide (T L P R N S G A G A S) corresp. to 858 868 human GluR1 recombinant fusion protein containing GST and NMDAR1 660 811 fusion protein (amino acid 1 564 ) of NMDA NR1 fusion protein from 1 564 NMDA NR1 Amino acid region 1099 1213 from human NMDA R2A produced as a GST fusion protein C-terminal fusion protein of the NMDA R2B, 984 1104 , 30kD synthetic peptide corresp. to 1297 1309 (C K L R R Q H (pS) Y D T F V D) of human phospho-NR2B with an N-terminal cysteine added for KLH conjugation thyroglobulin-conjugated, synthetic peptide (L I P Q Q (pS) I N E A I K) corresp. to 826 836 GluR1 mature chain, with a phosphorylated serine at position 831 recombinant fusion protein TrpE-GluR2 (putative N-terminal portion, 175 430 ). synthetic peptide (V A K N P Q N I N P S S S Q N S) corresp.to 827 842 the rat GluR2 synthetic peptide (L V Y G I E (pS) V K I A) corresp. to 873 883 rat GluR2, with a phosphorylated serine at position 880,Thyroglobulin-conjugated. synthetic peptide corresp. to 864 883 (C Q N F A T Y K E G Y N V Y G I E S V K I) of rat GluR2 (KLH coupled). synthetic peptide corresponding to 864 883 rat GluR2 GST fusion protein corresponding to 1299 1492 mouse Notch 1 synthetic peptide C Q H S Y S S P V D N T P S H Q corresp. to aa 2488 2502 human Notch 1, intracellular domain synthetic peptide (V L L S R K R R R Q H G Q-C) 1755 1767 at N-terminal sequence of the cleaved N intracellular domain (NICD). synthetic peptide, V L L S R K R R R Q H G Q C, corresp. to amino acid 1755 1767 human Notch 1 N-terminal GST fusion protein corresponding to 381 853 rat Notch 1 synthetic peptide (C Q H S Y S S P V D N T P S H Q) corresp. to 2488 2502 the intracellular domain of human Notch 1 synthetic peptide corresp. to aa 2507 2520 human Notch 1, intracellular domain, 35 amino acids from the C-terminus. synthetic peptide C N A A E R T P S H S G H L Q corresp. to aa 2396 2409 human Notch 2, intracellular domain synthetic peptide (T H M S E P P H N N M Q V Y A) corresp. to 2457 2471 the human NOTCH homolog 2 protein synthetic peptide (Q L G P Q P E V T P K R Q V L A) corresp. to 2306 2321 the human NOTCH homolog 3 protein (KLH coupled). his-tag fusion protein containing the C-terminus 5935 6454 murine Notch 3 his-tag fusion protein containing the C-terminus 5708 6217 murine Notch 4 synthetic peptide (C G P P A L Q E M P I N Q G G E G K K) corresp. to 1984 2002 the human NOTCH homolog 4 (NOTCH4) protein. synthetic peptide comprised of 1204 1218 [D L E S A Q S L N R M E Y I V] of the human jagged 1 (JAG1) protein coupled to KLH synthetic peptide comprised of 1224 1238 [R A V R S I N E A R Y A G K E] of the human jagged 2 (JAG2) protein coupled to KLH synthetic phospho-peptide K(123)R R E I L S R R P S (pS) Y R K (136) corresp. to aa 123 136 from human CREB synthetic peptide, corresponding to 6 23 human CREB synthetic peptide K R R E I L S R R P S Y R K corresp. to 123 136 human CREB. synthetic peptide corresponding to a region near the N-terminus ( 5 45 ) of human CREB synthetic peptide corr. to 281 294 rat CaM kinase II with the phospho. threonine at position 286 synthetic phospho peptide (V R R G S G T P E A E A P R Q) corr. to 499 513 human CaMKII beta synthetic peptide: C T R F T D E Y Q L F E E L corresp. to N terminal 7 20 rat CaMKII (delta isoform ) synthetic peptide corr. to 281 294 rat CaM kinase II with the phospho. threonine at position 286 fusion protein, corresponding to 1 564 NMDAR1 C-terminal fusion protein, corresponding to 1253 1391 rat NMDA receptor 2B N-terminal fusion protein corresponding to 25 130 rat NMDA receptor 2C. fusion protein, corresponding to 780 914 from the intracellular IIIIV loop of Human NR3A + NR3B. 1437 1456 mature mouse NR2B or 1463-1482 of NR2B precursor; signal is amino acid residues 1-26 [K F N G S S N G H V Y E K L S S I E S D V] fusion protein from 1 564 NMDA NR1 C- terminal fusion protein representing 1253 1391 rat NMDAR2A C- terminal fusion protein representing 1253 1391 rat NMDAR2B N-terminal fusion protein (17 kDa) representing 25 130 rat NMDAR2C fusion protein, corresponding to 1 564 NMDAR1 fusion protein, corresp. to 780 914 from the intracellular IIIIV loop of Human NR3A + NR3B. synthetic peptide corr. to 281 294 rat CaM kinase II with the phospho. threonine at position 286 synthetic peptide: C T R F T D E Y Q L F E E L corresp. to N terminal 7 20 rat CaMKII (delta isoform ) synthetic phospho peptide (VRRGSGTP EAEAPRQ) corr. to 499 513 human CaMKII beta synthetic phospho-peptide K(123)R R E I L S R R P (pS) Y R K (136) corresp. to aa 123 136 from human CREB synthetic peptide corresponding to a region near the N-terminus ( 5 45 ) of human CREB synthetic peptide K R R E I L S R R P S Y R K corresp. to 123 136 human CREB. synthetic peptide, corresponding to 6 23 human CREB synthetic phospho-peptide K(123) R R E I L S R R P (pS) Y R K (136) corresp. to aa 123 136 from human CREB synthetic phospho-peptide derived from 74 128 human CREB synthetic phospho-peptide derived from 74 128 human CREB synthetic peptide C R D A S N H K R R E P V G Q D corresp. to 1719 1733 human activated Notch2 peptide C N A A E R T P S H S G H L Q corresp. to 2396 2409 Notch 2 peptide C E H P F L T P S P E S P D Q corresp. to 2507 2520 at the C-terminus of Notch 1 peptide V L L S R K R R R Q H G Q C corresp. to 1755 1767 the N-terminal sequence of the cleaved N intracellular domain (NICD). synthetic peptide K A S R G N D R N R I V L P F S C corresp. to 110 125 Human Jagged1 coupled to KLH synthetic peptide (A W H A P G D D L R P E A L C) corresp. to 121 134 human Delta4, coupled to KLH fusion protein from 1 564 NMDA NR1 C- terminal fusion protein representing 1253 1391 rat NMDAR2A C- terminal fusion protein representing 1253 1391 rat NMDAR2B N-terminal fusion protein (17 kDa) representing 25 130 rat NMDAR2C peptide V L L S R K R R R Q H G Q C corresp. to 1755 1767 the N-terminal sequence of the cleaved N intracellular domain (NICD). synthetic peptide: C Q H S Y S S P V D N T P S H Q corresp. to 2488 2502 Notch1 intra peptide C E H P F L T P S P E S P D Q corresp. to 2507 2520 at the C-terminus of Notch 1 synthetic peptide C R D A S N H K R R E P V G Q D corresp. to 1719 1733 human activated Notch2 peptide C N A A E R T P S H S G H L Q corresp. to 2396 2409 Notch 2 synthetic peptide (A W H A P G D D L R P E A L C) corresp. to 121 134 human Delta4, coupled to KLH fusion protein of NR3A aa 780 914 from the extracellular III-IV loop fusion protein containing 175 430 from the N-terminal region of GluR2. synthetic peptide corresp. to 1116 1130 the rat mGluR1α coupled to bovine thyroglobulin with glutaraldehyde fusion protein from 1 564 NMDA NR1 KLH conj. synthetic peptide corr. to 2542 2554 Notch1 KLH conj. synthetic peptide corr. to 2457 2471 human Notch2 KLH conj. synthetic peptide corr. to 2306 2321 human Notch3 KLH conj. synthetic peptide corr. to 1984 2002 human Notch4 KLH conj. synthetic peptide corr. to 1204 1218 human Jagged1 KLH conj. synthetic peptide corr. to 1224 1238 human Jagged2 1 290 human CREB-2 254 327 mapping within the DNA binding and dimerization domain of human CREB-1 p43 254 327 mapping within the DNA binding and dimerization domain of humrn CREB-1 p43 254 327 human CREB-1 303 478 mapping at the C-terminus of mouse CaMKIIα 1 300 mapping at the N-terminus of human CaMKIIα 303 478 mouse CaMKII 303 478 mouse CaMKIIα 20 150 mapping within an extracellular domain of human Notch 1 1779 2003 mapping at the C-terminus of mouse Notch 4 25 255 mapping within an extracellular domain of human Notch 2 2107 2240 mouse Notch 3 amino acid 1299 1492 (region EGF repeat 33 through LNG repeat 1) of mouse Notch 1 207 272 human Jagged 1110 1223 human Jagged 459 723 human Delta 1253 1391 , unconjugated fusion protein encoding the putative extracellular N-terminal domain of GluR2 ( 170 430 ) 448 468 at C-terminal of rat CaMKinase II α 448 460 at C-terminal of rat CaM Kinase IIα 448 460 at C-terminal of rat CaM Kinase IIα fusion protein containing 1 564 the NR1-subunit of rat NMDA Receptor. fusion protein from 1 564 NMDA NR1 peptide corresp. to 7 20 rat multi-functional CaMKinase II Δ isoform conjugated to KLH recombinant human CREB ( 136 341 ) derived from E. coli purified, NS0-derived, recombinant rat Notch-1 ( 20 488 ) purified, NS0-derived, recombinant rat Notch-2 ( 26 492 ) purified, NS0-derived, recombinant rat Notch-2 ( 26 492 ) purified, Sf21-derived, recombinant mouse Notch-3 ( 40 468 ) purified, Sf21-derived, recombinant mouse Notch-3 ( 40 468 ) purified, NSO-derived, recombinant human Jagged 1 ( 1 296 ) purified, NSO-derived recombinant human Jagged-1 ( 1 296 ) purified, NSO-derived recombinant human Jagged-1 ( 1 296 ) purified, NS0-derived, recombinant human Jagged 2 ( 27 307 ) purified, E. coli-derived, recomb. human CBP ( 2141 2442 ) synthetic peptide ( 7 20 ) from rat CaM kinase II, conj. to KLH synthetic peptide ( 7 20 ) from rat CaM Kinase II, conj. to KLH phospho peptide corresp. to 122 147 region of human CREB peptide corresp. to 5 45 near the N-terminus of human CREB conjugated to KLH synthetic peptide corresp. to 6 23 human CaMKinase II protein synthetic peptide (V L L S R K R R R Q H G Q-C)corresp. to 1755 1767 human Notch-1 (NICD) synthetic peptide (C-Q H S Y S S P V D N T P S H Q) corresp. to 2488 2502 human Notch1. synthetic peptide (C-E H P F L T P S P E S P D Q) corresp. to aa 2507 2520 human Notch-1 synthetic peptide corresponding to aa 2396 2409 human Notch-2 synthetic peptide corresponding to 121 134 human Delta-4 synthetic peptide (C-G E E W S Q D L H S S G R T D L R Y S) corresp. to 155 173 mouse DELTA-1 synthetic peptide corresp. to aa 123 137 (K R R E I L S R R P S Y R K C) of human CREB, coupled to KLH synthetic peptide (K W Q I V H F H R S G A P S V L P H) corresp. to the C-terminal 461 478 ) region of rat CaMKinase IIα peptide phosphorylated at Thr286 (M H R Q E pT V D C L K K F N), corresp. to 281 294 rat and mouse CaM Kinase IIα subunit synthetic peptide 918 938 corresp. to the C-terminus of rat NMDAR1 conjugated to KLH 1253 1391 from the C-terminal portion of NMDA2A (NR2A) synthetic peptide corresp. to 1449 1464 at the C-terminus of rat NMDAR2A 984 1104 at C-terminus of NR2B 25 130 at N-terminal of NR2C synthetic peptide (K W Q I V H F H R S G A P S V L P H) corresp. to C-terminal 461 478 ) of rat CaM Kinase IIα recomb. protein containing 660 811 the NMDA R1 receptor recomb. protein containing 660 811 the NMDA R1 receptor synthetic peptide corresp. to 100 150 human CREB synthetic peptide corresp. to 281 288 conjugated to KLH purified, NSO-derived, recombinant human Jagged-2 ( 27 307 ) 14 residue synthetic peptide CTRFTDEYQLFEEL based on rat multifunctional calmodulin dependent kinase II delta isoform ( 7 20 ) coupled to KLH. synthetic peptide corresp. to 100 150 human CREB phospho peptide corresp. to 122 147 region of human CREB 254 327 mapping within the DNA binding and dimerization domain of humrn CREB-1 p43 254 327 human CREB-1 peptide corresp. to 5 45 near the N-terminus of human CREB conjugated to KLH 254 327 mapping within the DNA binding and dimerization domain of human CREB-1 p43 1 290 human CREB-2 14 residue synthetic peptide CTRFTDEYQLFEEL based on rat multifunctional calmodulin dependent kinase II delta isoform ( 7 20 ) coupled to KLH. 303 478 mouse CaMKII 1 300 mapping at the N-terminus of human CaMKIIα 303 478 mapping at the C-terminus of mouse CaMKIIα 303 478 mouse CaMKIIα synthetic peptide based on sequence from rat/mouse CaMKIIa ( 281 294 ), thio phosphorylated at auto phosphorylation residue Thr-286, conjugated synthetic peptide based on sequence from rat/mouse CaMKIIa ( 281 294 ), thio phosphorylated at auto phosphorylation residue Thr-286, conjugated synthetic peptide (V L L S R K R R R Q H G Q-C)corresp. to 1755 1767 human Notch-1 (NICD) synthetic peptide (C-Q H S Y S S P V D N T P S H Q) corresp. to 2488 2502 human Notch1. synthetic peptide (C-E H P F L T P S P E S P D Q) corresp. to aa 2507 2520 human Notch-1 synthetic peptide corresponding to aa 2396 2409 human Notch-2 amino acid 1299 1492 (region EGF repeat 33 through LNG repeat 1) of mouse Notch 1 20 150 mapping within an extracellular domain of human Notch 1 25 255 mapping within an extracellular domain of human Notch 2 2107 2240 mouse Notch 3 1779 2003 mapping at the C-terminus of mouse Notch 4 914 1056 human Jagged2 19 318 within an extracellular domain of human NMDAζ1 23 76 within an extracellular domain of human NMDAε1 27 76 within an extracellular domain of human NMDAε2 268 386 human NMDAε4 268 386 corr. to an internal region of human NMDAε4 19 318 within an extracellular domain of human NMDAζ1 23 76 within an extracellular domain of human NMDAε1 27 76 within an extracellular domain of human NMDAε2 268 386 corr. to an internal region of human NMDAε4 synthetic peptide (VAKNPQNIN PSSSQNS) corr. to 827 842 from the C-terminus of rat GluR2 6His-tagged fusion protein corresponding to 7 305 ferret CaM Kinase II γ-subunit synthetic thiophos-phated (Thr286) peptide corresp. to 281 294 from the α-subunit of mouse and rat CaM kinase II synthetic peptide corresponding to 125 135 CREB phosphorylated at Ser133 synthetic peptide corresponding to 6 23 human CREB-1 synthetic peptide corresponding to 6 23 human CREB-1 peptide corresp. to 5 45 near the N-terminus of human CREB conjugated to KLH synthetic peptide corresponding to 123 136 human CREB synthetic phospho-peptide corresponding to 123 136 human CREB phospho peptide corresp. to 122 147 region of human CREB synthetic peptide corresponding to 125 135 CREB phosphorylated at Ser133 synthetic peptide based on sequence from rat/mouse CaMKIIa ( 281 294 ), thio phosphorylated at auto phosphorylation residue Thr-286, conjugated synthetic phospho-peptide corresponding to 123 136 rat CREB coupled to KLH CREB-1 (p43) peptide corresponding to the N-terminal 5 45 human protein conjugated to KLH phosphorylated (Thr286) peptide corresponding to 281 294 (M H R Q E T V D C L K K F N) of the mouse/rat CaM kinase II α subunit synthetic peptide corresp. to 6 23 human CaMKinase II protein synthetic peptide selected within 400 478 human CAMK2α synthetic peptide selected within 500 550 human CAMK2β. synthetic peptide selected from 397 411 human CAMK2γ. synthetic peptide selected within 450 499 human CAMK2δ synthetic peptide selected from 324 338 human CAMK2 δ-like rat CaMK II synthetic peptide ( 7 20 ), conjugated to KLH synthetic peptide corresponding to 281 294 rat CaM Kinase II α-subunit synthetic peptide (KMHRQE[pT]VDCLK) correspond. to 281 291 rat CaM Kinase II α-subunit synthetic peptide corresponding to 281 294 rat CaM Kinase II α-subunit rat CaMK II synthetic peptide ( 7 20 ), conjugated to KLH synthetic peptide (KMHRQE[pT]VDCLK) correspond. to 281 291 rat CaM Kinase II α-subunit synthetic peptide based on sequence from rat/mouse CaMKIIa ( 281 294 ), thio phosphorylated at auto phosphorylation residue Thr-286, conjugated synthetic phospho-peptide corresp. to 826 836 mature GluR1 from mouse and rat synthetic peptide corresp. to 840 850 the mature chain, with a phosphorylated serine at position 845. recomb. fusion protein TrpE-GluR2 (N-terminal portion, 175 430 rat GluR2) synthetic peptide from 827 842 , of rat GluR2 conj. to BSA through a cysteine added to the C-terminus C-terminal synthetic peptide sequence corresponding to 894 907 rat GluR1 coupled to bovine thyroglobulin with glutaraldehyde synthetic phospho-peptide corresponding to 891 902 rat NMDA receptor subunit NR1 synthetic phospho-peptide corresp. to 891 902 rat NMDA receptor subunit NR1 fusion protein containing 1 564 rat NMDA NR1 fusion protein from 1 564 rat NMDA NR1 fusion protein containing 984 1104 NMDAR 2B subunit fusion protein containing 1253 1391 NMDAR 2A-subunit a 17 kDa fusion protein constructed from the N-terminal region 25 130 the rat NMDAR 2C subunit synthetic peptide (C-E H P F L T P S P E S P D Q) corresp. to aa 2507 2520 human Notch-1 synthetic peptide (V L L S R K R R R Q H G Q-C)corresp. to 1755 1767 human Notch-1 (NICD) synthetic peptide (C-Q H S Y S S P V D N T P S H Q) corresp. to 2488 2502 human Notch1. synthetic peptide corresponding to aa 2396 2409 human Notch-2 GST-fusion protein containing 1299 1492 mouse Notch 1 GST-fusion protein corresponding to aa 381 853 rat Notch 1 GST-fusion protein corresponding to aa 2272 2488 rat Notch 1 His-tag fusion protein containing the C-terminus 5708 6217 murine Notch 4 GST fusion protein corresponding to 2272 2488 rat Notch 1 His-tag fusion protein containing the C-terminus 5935 6454 murine Notch 3 GST fusion protein comprising 1299 1492 mouse Notch 1 synthetic peptide 10 30 aa in length) at the C-term of last 50 aa of human Jag1 synthetic peptide 10 30 aa in length) of last 50 aa at the C-term of human Jag2 fusion protein containing aa 1253 1391 C-terminal of rat brain subunit 2A fusion protein containing aa 984 1104 C-terminal of rat brain subunit 2B fusion protein containing aa 25 130 N-terminal of rat brain subunit 2C full length bovine brain protein. Epitope 1 151 full length bovine protein. Epitope 997 1332 synthetic peptide: P K K K P T P I Q L N P corresp. to 1 12 MEK1 with a terminal cysteine, coupled to KLH Synthetic peptide: (C)Y N H R T D L F K S F P G P, corresp. to 590 603 human ADAMTS4, with N-terminally added cysteine synthetic peptide: K N G Y Q S D A K G V K T F, corresp. to 636 649 human ADAMTS5 with N-terminally added cysteine. two synthetic peptides, conjugated to KLH, derived from within 1 50 and 450-610 of human SIRT1 synthetic peptide: A T R Q E L T D V N Y P S D K S (with C-terminal added lysine), corresp. to C terminal 722 737 mouse SIRT1 synthetic peptide 10 30 aa in length) at the N-term of first 50 aa of human MAP2, KLH conjugated synthetic peptide 10 30 aa in length) at the C-term of last 50 aa of human MAP2 synthetic peptide 10 30 aa in length) in the region of 302~318 of human MAP4K2, KLH conj. synthetic peptide selected from the sequence of human MAPK10 within 1 100 , KLH conj. synthetic peptide selected from the sequence of human MAPK11 within 300 400 , KLH conj. synthetic peptide selected from the sequence of human MAPK12 within 300 400 , KLH conj. synthetic peptide selected from the sequence of human MAPK13 within 300 400 , KLH conj. synthetic peptide selected from the sequence of human MAPK14 within 200 300 , KLH conj. synthetic peptide selected from the sequence of human MAPK8 within 200 300 , KLH conj. synthetic peptide selected from the sequence of human MAPK9 within 200 300 , KLH conj. synthetic peptide selected from the sequence of human MAP2K1 within 1 100 , KLH conj. synthetic peptide selected from the sequence of human MAP2K2 within 1 100 , KLH conj. synthetic peptide selected from the sequence of human MAP2K6 within 1 100 , KLH conj. synthetic peptide selected from the sequence of human MAP2K6 within 250 350 , KLH conj. synthetic peptide selected from the sequence of human MAP3K9 within 300 400 , KLH conj. synthetic peptide selected from the sequence of human MAP3K9 within 1 100 , KLH conj. synthetic peptide 10 30 aa in length) at the C-term of last 100 aa of human Sirt1, KLH coupled C-terminus
( 343 358 ) ( 351 368 ) N-terminus
( 87 99 ) synthetic peptide C-T Y D E V I S F V P P P L D Q E E M E S based on the human p38 ( 341 360 ), coupled to KLH (sequence identical to mouse) synthetic peptide: C A A G P E M V R G Q V F corresp. to 9 19 human ERK2 synthetic peptide C S A Y D A R L R Q K V A V K corresp. to 39 53 human MAPK11 recombinant fragment, corresp. to 232 360 human ERK2 A 12 residue synthetic peptide A A G P E M V R G Q V F (C) based on the rat ERK2 ( 6 17 ), coupled to KLH Synthetic peptide: C A A G P E M V R G Q V F, corresp. to 9 19 human ERK2 synthetic peptide (C) D R L T A E E A L S H P Y M, corresp. to 303 325 rat ERK3 with a added cysteine residue, coupled to KLH synthetic peptide M A E P L K E E D G E D G S corresp. to N- terminal 1 14 human ERK5 coupled to KLH synthetic peptide D E Q E A L D S I M K D L V A L Q-C corresponding to 2 18 mouse MEKK3, conj. to KLH synthetic peptide, corresp. to 334 349 ERK5 synthetic peptide corresp. to 350 400 human ERK1 conjugated to KLH recombinant fragment, corresp. to 232 360 human ERK2 synthetic peptide H S S S E R F L E Q S H S S M E, corresp. to 401 416 human ERK3 synthetic peptide selected from the sequence of human MAP2K2 within 200 300 , KLH conj. synthetic peptide derived from 317 339 within the C-terminal half of the human ERK1 protein. synthetic peptide derived from aa 334 349 human ERK5/BMK1 protein peptide derived from 317 339 human ERK1 (MAPK). Sequence conserved in human and rat. synthetic peptide corresp. to 1356 1375 human ASK1 a 14 residue synthetic peptide A P G G G G G E P R G T A G (C) based on rat ERK1 MAP kinase ( 7 20 ) with an added cysteine and coupled to KLH synthetic peptide selected from the sequence of human MAPK10 within 1 100 conj. to KLH synthetic peptide selected from the sequence of human MAPK11 within 300 400 synthetic peptide selected from the sequence of human MAPK12 within 300 400 , conj. to KLH synthetic peptide selected from the sequence of human MAPK13 within 300 400 synthetic peptide selected from the sequence of human MAPK14 within 200 300 conj. to KLH synthetic peptide selected from the sequence of human MAPK8 within 200 300 conj. to KLH synthetic peptide selected from the sequence of human MAPK9 within 200 300 conj. to KLH a 35 residue synthetic peptide corresp. to 333 367 rat ERK1 MAP kinase with the CGG spacer group added, coupled to KLH a 23 residue 303 325 ) synthetic peptide (C) D R L T A E E A L S H P Y M S I Y S F P T D E based on the rat ERK3 coupled to KLH synthetic peptide selected within 1 50 human ERK1, conj. to KLH synthetic peptide selected from 269 285 human ERK2 synthetic peptide selected from 707 721 human ERK3, coupled to KLH synthetic peptide slected from 542 557 human ERK4 synthetic peptide 10 30 aa in length) at the N-term of first 50 aa of human MAP2, KLH conjugated synthetic peptide 10 30 aa in length) at the C-term of last 50 aa of human MAP2 synthetic peptide from 1 13 rat MEK2 coupled to KLH a 17 residue 2 18 ) synthetic peptide D E Q E A L D S I M K D L V A L Q(C) based on mouse MEKK3 with an added cysteine coupled to KLH a 16 residue 59 74 ) synthetic peptide A F E Y E D E D G D R I T V R S(C) based on human and rat MEK5 with added cysteine and coupled to KLH a 12 residue 1 12 )synthetic peptide M P K K K P T P I Q L N(C) coupled to KLH a 15 residue 320 334 ) peptide (C)K G T D V A S F V K L I L G D based on human MEK6 with an added cystein and coupled to KLH a 26 residue 654 669 ) synthetic peptide (C)Q D R P P S R E L L K H P V F R based on murine MEK kinase with an added cysteine and coupled to KLH synthetic peptide selected from 1 17 human MEK1 synthetic peptide selected from 1 17 human MEK2 conjugated to KLH synthetic peptide selected from 425 438 human MEK synthetic peptide selected from 1143 1159 human MEKK1 synthetic peptide selected from 138 153 human MEKK2 conj. to KLH synthetic peptide selected from 124 141 human MEKK3 synthetic peptide selected from 1081 1097 human MEKK4 synthetic peptide selected from 1282 1297 human MEKK5 synthetic peptide selected from 765 781 human MEKK6 synthetic peptide selected from 428 445 human MEKK8 conj. to KLH KLH conjugated peptide corr. to 76 87 human ASK-1 protein. peptide sequence corresp. to 1356 1375 human ASK1 synthetic peptide: E E K D Q E I K H L K L K S Q P corresp. to 1276 1291 ASK1 with C-terminally added cysteine coupled to KLH peptide corresp. to 76 87 human ASK-1 protein conj. to KLH peptide corresp. to 1356 1375 human ASK1 synthetic peptide 10 30 aa in length) at the C-term of last 100 aa of human Sirt1, KLH coupled synthetic peptide corresponding to positions 325 345 the intact MAP kinase 764 837 human ADAMTS-4 peptide corresp. to 333 367 rat ERK1 conj. to KLH 1 300 mapping at the N-terminus of human MAP-2 2211 2510 human MAP-1A 2221 2350 human MAP-1B 1 50 mapping at the N-terminus of human MAP-1A light chain 3 997 1332 bovine high molecular weight MAP-2 isoforms peptide corresp. to 1 28 human MAP2K1 37 92 mapping at the C-terminus of human S-100 β chain 448 747 human SIRT1 565 721 mapping at the C-terminus of human ERK3 416 815 mapping at the C-terminus of human ERK 5 229 318 mapping at the C-terminus of human MEK-3/6 302 399 mapping at the C-terminus of human MEK-4 351 444 mapping at the C-terminus of human MEK-5 1 160 mapping at the N-terminus of human MEK-7 1 160 human MEK-7 1076 1375 human ASK1 1076 1375 human ASK1 2211 2510 human MAP-1A 2221 2350 human MAP-1B 997 1332 bovine high molecular weight MAP-2 isoforms 1 300 mapping at the N-terminus of human MAP-2 1 50 mapping at the N-terminus of human MAP-1A light chain 3 37 92 mapping at the C-terminus of human S-100β 1 154 representing full length human SOD-1 1 154 human SOD-1 1 222 representing full length human SOD-2 1057 1178 mapping near the C-terminus of human SOS 1 1057 1178 mapping near the C-terminus of human Sos 1 339 353 rat ERK1 synthetic peptide (C G G P F T F D M E L D D L P K E R L K E R L K E I F Q E T A R F Q P G A P E A P) corresp. to 333 367 rat ERK1 MAP kinase plus CGG spacer group and coupled to KLH synthetic peptide (A A G P E M V R G Q V F C) corresp. to 6 17 rat ERK2, with a cysteine (C) added and coupled to KLH synthetic peptide (H A F I K R S D A E E V D F A G W L C) corresp. to 359 377 human MEK1 coupled to KLH synthetic peptide (M P K K K P T P I Q L N C) corresp. to 1 12 rat MEK1 with cysteine (C) added and coupled to KLH synthetic peptide corresp. to 59 74 human and rat MEK5 with an added cysteine (C)and coupled to KLH synthetic peptide (T Y D E Y I S F V P P P L D Q E E M E S) corresp. to 341 360 p38 MAP kinase synthetic peptide (G R L V D S K A K T R S A G C) corresp. to 266 280 human MKK7 peptide corresp. to 1243 1258 (K K S D H G N A F F P N S P S P) of murine Son of Sevenless Homolog 1 Protein (SOS 1) peptide corresp. to 551 599 human Sirt1 peptide corresp. to 1356 1375 human ASK1 synthetic peptide derived from 317 339 within the C-terminal half of human ERK1 protein N-terminal 11 28 ERK-1 232 360 from human ERK-2 401 416 human ERK-3 N-terminus 2 140 human ERK5 N-terminal 341 570 human ERK-5 amino acid 1 28 MAP2K1 997 1332 of MAP2 213 360 p38 of human origin 213 360 p38 of human origin amino acids 281 360 mapping within an internal region of MEK kinase-2 of human origin amino acids 291 360 mapping within an internal region of MEK kinase-3 of human origin amino acids 1531 1607 mapping at the C-terminus of MEK kinase-4 of human origin 1 393 representing full length MEK-1 of human origin a peptide corresp. to 1360 1372 human ASK1 a synthetic peptide (RGGMLCTLW KAIIDFRNKQT)corresp. to 1356 1375 human ASK1