From W3C Wiki
- Josh Mandel
- Gökçe Banu Laleci Erturkmen
- Mustafa Yuksel
- Emory Fry
- Connor Dowling
- Eric Prud'hommeaux, W3C
For many clinical research or clinical informatics projects, the most expensive opperation is mapping values in one terminology to another. This work is frequently seen as project-specific but has extensive overlap with other similar projects. This task is to create an exchange of project-specific mappings and the parameters that qualify how others may use them.
- Initially scope to one domain: Ontology of diseases.
- Find the commonalities between two existing systems (SALUS and TAPS)
- Derive minimal intersecting requirements (and expressivity)
- Parameterize factors which interfere with identical mappings (e.g. for X disease,
Folks we need to engage in this work:
- FDA working on Therapeutic Areas for clinical trial metadata interop.
- Pharmas largely unable to find and access similar trial data.
| project || clinical || pharmacological || ...
| SALUS || ICD10GM, ICD9CM, SNOMED CT (Clinical Findings), MedDRA || ATC || We have partial mappings between ICD9CM to SNOMED CT (based on the mappings provided by OMOP Project). We can share this. We have partial mappings between Snomed CT to MedDRA based on OntoADR Ontology, we are still working on the mappings between ICD10GM to Snomed CT. Due to licensing issues, this cannot be shared directly.
| TAPS || ICD9 || RxNorm || Emory and Connor to fill in
Both are using skos:narrower to capture hierarchy placement and
skos:exactMatch for identical concepts.
| Term1 || predicate || Term2 || context || ...
| ICD9:123.4 || exactMatch || SNOMED:1234567 || context1
| SNOMED:1234567 || exactMatch || Medra:98765432 || context2
| ICD9:123.4 || exactMatch || Medra:98765432 || too inclusive, e.g. heart attack coded in ICD9 would be athlete's foot in Medra
| name || domain || from || to || description
| OMOP || drug outcomes || ICD9 || SNOMED || project cataloging the outcomes of medications