14:56:26 RRSAgent has joined #hcls 14:56:26 logging to http://www.w3.org/2009/07/23-hcls-irc 14:56:33 Zakim, this is hcls 14:56:33 ericP, I see SW_HCLS()11:00AM in the schedule but not yet started. Perhaps you mean "this will be hcls". 14:56:39 Zakim, this will be hcls 14:56:39 ok, ericP; I see SW_HCLS()11:00AM scheduled to start in 4 minutes 14:56:44 Zakim, please dial ericP-office 14:56:44 ok, ericP; the call is being made 14:56:45 SW_HCLS()11:00AM has now started 14:56:46 +EricP 14:56:58 agenda? 14:57:22 agenda+ SBML & the Semantic Web - Mike Hucka 14:57:34 agenda+ ISWC Workshop Update - Susie 14:57:45 agenda+ Next F2F, Nov. 2-6, Santa Clara, CA - Susie 14:57:50 agenda+ AOB 15:00:30 + +1.732.354.aaaa 15:00:46 KevinDoyle has joined #HCLS 15:00:57 Zakim, +1.732.354.aaaa is SusieS 15:00:57 +SusieS; got it 15:01:29 + +1.781.839.aabb 15:01:41 Zakim, +1.781.839.aabb is Julia 15:01:41 +Julia; got it 15:01:50 + +1.860.255.aacc 15:01:53 + +1.617.395.aadd 15:02:06 Zakim, +1.860.255.aacc is Oliver 15:02:06 +Oliver; got it 15:02:19 Zakim, +1.617.395.aadd is KevinD 15:02:19 +KevinD; got it 15:03:12 Zakim, who is speaking? 15:03:22 ericP, listening for 10 seconds I heard sound from the following: Oliver (42%) 15:04:15 topic: administrivia 15:04:42 +[IPcaller] 15:04:44 Jim has joined #hcls 15:05:00 Zakim, [IPcaller] is MikeHucka 15:05:00 +MikeHucka; got it 15:05:14 we're here at Uchc 15:05:57 mhucka has joined #HCLS 15:06:08 Zakim, who is here? 15:06:11 On the phone I see MikeHucka, EricP, SusieS, Julia, Oliver, KevinD 15:06:13 MIke Hucka 15:06:14 On IRC I see mhucka, Jim, KevinDoyle, RRSAgent, Zakim, curoli, AlexPassant, Cloud_, ericP 15:07:17 scribenick: ericP 15:07:52 ericP has changed the topic to: http://drop.io/mhucka_hcls_2009_09_23/asset/mhucka-sbml-2009-07-23-pdf 15:08:16 remiss on task updates 15:08:16 please remember to send mail to public-semweb-lifesci 15:08:16 can prefix with [BioRDF] or whatever so folks can filter (on or off) if they want 15:09:12 Zakim, take up agendum 1 15:09:12 agendum 1. "SBML & the Semantic Web - Mike Hucka" taken up [from ericP] 15:09:45 Julia_Kozlovsky has joined #HCLS 15:11:34 [slide 2] 15:11:36 [slide 3] 15:12:04 [slide 4] 15:13:04 [slide 5] 15:14:03 mhucka: SBML focuses on modelable/simulatable processes 15:14:57 ... before 2000 there was no common model for exchange between software 15:16:50 mhucka: no limitation on the expressibility 15:17:19 s/expressibility/expressivity/ 15:17:57 mhucka: not procedural, so doesn't tell you e.g. how long to run 15:20:11 mhucka: people encode abstract models which are (intentionally) not bilogically feasible 15:21:13 ... the MathML does not support integrals 15:21:51 ... right hand side is a diff eq and left hand side is the rate of change of the species 15:23:43 ... events model things like a cell reaching a certain size and undergoing mitosis 15:25:46 mhucka: "validation" not all captured in XSD or UML, includes some SBML-specific pragmas 15:27:50 mhucka: evolved some process, e.g. editors elected for 3 years 15:29:09 mhucka: still adding formalism to SBML 15:30:34 mhucka: level2 added constructs like initial assignment 15:31:36 ... level3 components for things like shape 15:35:07 mhucka: SBML vars correspond to e.g. vars in papers 15:37:43 mhucka: Miriam provides (amoung other things) a minimal provenance model 15:38:33 mhucka: Miriam is not SBML-specific, but requires an SBML binding 15:42:03 Oliver: do you have to select the resources from the miriam list? 15:42:36 mhucka: for longevity, you want to have confidence in the URL 15:42:46 ... had some troubles with LSIDs 15:43:47 ... added a redirection 15:43:55 ... e.g. GO has changed over the years 15:45:03 Oliver: would i use a Uniprot ID or a Miriam ID? 15:46:08 mhucka: encourage urn:miriam:... to abstract location 15:49:11 mhucka: bqbiol = AKA 15:50:21 JimS: we have RDF beyond basic Miram -- e.g. tying to BioPAX 15:50:30 ... can we add what we want? 15:51:15 mhucka: Miriam-SBML is minimal 15:51:28 ... at dev time, many langs didn't have RDF parsers 15:51:46 ... you can add whatever, but there's no guarantee that tools will understand it 15:52:56 ... put your additional RDF after the SBML-controlled bits 15:54:39 [BioModels advanced search page] 15:55:18 [slide 31 is a screenshot of the BioModels advanced search page] 15:58:00 Zakim, take up next agendum 15:58:00 agendum 2. "ISWC Workshop Update - Susie" taken up [from ericP] 15:58:17 susie: wrote a blog and email nagging folks to submit papers 15:58:29 ... deadline in 10 days 15:59:05 Zakim, take up agendum 1 15:59:05 agendum 1. "SBML & the Semantic Web - Mike Hucka" taken up [from ericP] 15:59:28 [slide 32: bleeding edge] 15:59:41 -SusieS 15:59:50 mhucka: should also include sybil (SP?) - integrating BioPAX and SBML 16:00:27 -Julia 16:00:30 mhucka: first bullet: rich anntations enhance identy and enable model merging 16:01:16 ... second bullet: MFO accesses Systems Biology Ontology 16:01:58 ... third bullet: paper at last ISMB 16:02:46 [slide 35: kudos and upcoming meeting] 16:03:30 Oliver: re: extra RDF, is the parser generic RDF? 16:03:49 mhucka: some folks would like to change that 16:04:07 holger_stenzhorn has joined #hcls 16:04:11 ... may have been a design flaw, but goal was to make it easy for tools 16:04:37 holger_stenzhorn has left #hcls 16:05:54 ericP: i think it was a good engineering soln. will want to lift constraint when folks want to use generic serializer 16:08:16 SBML Level 2 Version 4 specification document: http://precedings.nature.com/documents/2715/version/1 16:08:36 Section 6 describes the RDF bits, see especially p. 93 16:10:06 ericP: do you have RDF-like extensibility in the rest of SBML? 16:10:16 mhucka: extensibility point is in the annotations 16:11:27 ... the packages that layer on the core, add elements and attributes to add representational power 16:11:38 I have to split. Thanks for all of the info. 16:11:44 KevinDoyle has left #HCLS 16:11:48 -KevinD 16:12:14 ericP: if you use these modules, should a naieve tool still interpret core? 16:12:33 mhucka: there's a mustUnderstand flag in the packages 16:13:42 ... mayUnderstand e.g. auxilliary picture 16:14:22 ... a tool interpreting the multi-@@@ package needs the package for complete understanding 16:17:04 mhucka: a level3 hierarchical model could be flattened into level2 16:20:24 ericP: @@@ interop ideas 16:20:29 mhucka: what sort of data? 16:20:45 ericP: pathways, receptors, GO 16:20:58 ... do you include the relationships between GO terms? 16:21:13 mhucka: not the relationships 16:21:32 ... an integrating query would have to make sense to some consumer 16:21:56 ... many SBML users are interesting in time/@@@3 simulation 16:22:18 ... maybe model creators who want to draw from other data sources 16:22:58 ... pathway expression use case would be interesting -- happening in Sibil (Oliver) 16:23:25 ... RDF-heads are trying to merge and verify models (U Newcastle) 16:23:45 ... the models are getting more complex and prohibitive to construct from scratch 16:23:59 ... composition will get more useful as models grow 16:26:54 ericP: @@@4 could it all be RDF? drug discovery scenario 16:27:29 mhucka: prolly could be all RDF. could then model more of the constraints 16:28:10 ... Allison Worcester (SP? gender?) MFO was doing that 16:28:40 Oliver: we're mirroring the core of SBML to RDF 16:28:40 Allyson Lister 16:28:49 ... project: SBPAX 16:29:30 ericP 16:29:35 ericP: PURLs? 16:30:00 mhucka: some detail made it easier to create our own resolution service 16:30:58 mhucka: long questions about what would be good to persue 16:33:53 -EricP 16:34:00 chair: ericP 16:34:03 -MikeHucka 16:34:06 RRSAgent, please draft minutes 16:34:06 I have made the request to generate http://www.w3.org/2009/07/23-hcls-minutes.html ericP 16:34:14 RRSAgent, please make log world-visible 16:39:03 disconnecting the lone participant, Oliver, in SW_HCLS()11:00AM 16:39:05 SW_HCLS()11:00AM has ended 16:39:06 Attendees were EricP, SusieS, Julia, Oliver, KevinD, MikeHucka